BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

308 related articles for article (PubMed ID: 21930926)

  • 1. Intermolecular transmission of superoxide dismutase 1 misfolding in living cells.
    Grad LI; Guest WC; Yanai A; Pokrishevsky E; O'Neill MA; Gibbs E; Semenchenko V; Yousefi M; Wishart DS; Plotkin SS; Cashman NR
    Proc Natl Acad Sci U S A; 2011 Sep; 108(39):16398-403. PubMed ID: 21930926
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Wild-type SOD1 overexpression accelerates disease onset of a G85R SOD1 mouse.
    Wang L; Deng HX; Grisotti G; Zhai H; Siddique T; Roos RP
    Hum Mol Genet; 2009 May; 18(9):1642-51. PubMed ID: 19233858
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis.
    Pokrishevsky E; Grad LI; Yousefi M; Wang J; Mackenzie IR; Cashman NR
    PLoS One; 2012; 7(4):e35050. PubMed ID: 22493728
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Palmitoylation of superoxide dismutase 1 (SOD1) is increased for familial amyotrophic lateral sclerosis-linked SOD1 mutants.
    Antinone SE; Ghadge GD; Lam TT; Wang L; Roos RP; Green WN
    J Biol Chem; 2013 Jul; 288(30):21606-17. PubMed ID: 23760509
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Superoxide dismutase 1 encoding mutations linked to ALS adopts a spectrum of misfolded states.
    Prudencio M; Borchelt DR
    Mol Neurodegener; 2011 Nov; 6():77. PubMed ID: 22094223
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oxidized/misfolded superoxide dismutase-1: the cause of all amyotrophic lateral sclerosis?
    Kabashi E; Valdmanis PN; Dion P; Rouleau GA
    Ann Neurol; 2007 Dec; 62(6):553-9. PubMed ID: 18074357
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Truncated wild-type SOD1 and FALS-linked mutant SOD1 cause neural cell death in the chick embryo spinal cord.
    Ghadge GD; Wang L; Sharma K; Monti AL; Bindokas V; Stevens FJ; Roos RP
    Neurobiol Dis; 2006 Jan; 21(1):194-205. PubMed ID: 16084730
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structures of the G85R variant of SOD1 in familial amyotrophic lateral sclerosis.
    Cao X; Antonyuk SV; Seetharaman SV; Whitson LJ; Taylor AB; Holloway SP; Strange RW; Doucette PA; Valentine JS; Tiwari A; Hayward LJ; Padua S; Cohlberg JA; Hasnain SS; Hart PJ
    J Biol Chem; 2008 Jun; 283(23):16169-77. PubMed ID: 18378676
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS.
    Ayers JI; Diamond J; Sari A; Fromholt S; Galaleldeen A; Ostrow LW; Glass JD; Hart PJ; Borchelt DR
    Acta Neuropathol; 2016 Dec; 132(6):827-840. PubMed ID: 27704280
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Aggregation modulating elements in mutant human superoxide dismutase 1.
    Karch CM; Borchelt DR
    Arch Biochem Biophys; 2010 Nov; 503(2):175-82. PubMed ID: 20682279
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms.
    Grad LI; Yerbury JJ; Turner BJ; Guest WC; Pokrishevsky E; O'Neill MA; Yanai A; Silverman JM; Zeineddine R; Corcoran L; Kumita JR; Luheshi LM; Yousefi M; Coleman BM; Hill AF; Plotkin SS; Mackenzie IR; Cashman NR
    Proc Natl Acad Sci U S A; 2014 Mar; 111(9):3620-5. PubMed ID: 24550511
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A prion-like mechanism for the propagated misfolding of SOD1 from in silico modeling of solvated near-native conformers.
    Healy EF
    PLoS One; 2017; 12(5):e0177284. PubMed ID: 28472188
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SOD1 oxidation and formation of soluble aggregates in yeast: relevance to sporadic ALS development.
    Martins D; English AM
    Redox Biol; 2014; 2():632-9. PubMed ID: 24936435
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure, folding, and misfolding of Cu,Zn superoxide dismutase in amyotrophic lateral sclerosis.
    Rakhit R; Chakrabartty A
    Biochim Biophys Acta; 2006; 1762(11-12):1025-37. PubMed ID: 16814528
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Metal-Free, Disulfide Oxidized Form of Superoxide Dismutase 1 as a Primary Misfolded Species with Prion-Like Properties in the Extracellular Environments Surrounding Motor Neuron-Like Cells.
    Takashima C; Kosuge Y; Inoue M; Ono SI; Tokuda E
    Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33923808
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models.
    Zetterström P; Stewart HG; Bergemalm D; Jonsson PA; Graffmo KS; Andersen PM; Brännström T; Oliveberg M; Marklund SL
    Proc Natl Acad Sci U S A; 2007 Aug; 104(35):14157-62. PubMed ID: 17715066
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Impairment of nuclear factor-kappaB activation increased glutamate excitotoxicity in a motoneuron-neuroblastoma hybrid cell line expressing mutant (G93A) Cu/Zn-superoxide dismutase.
    Pyo JS; Ko YS; Kim WH; Kim M; Lee KW; Nam SY; Chung HY; Cho SJ; Baik TK; Lee BL
    J Neurosci Res; 2010 Aug; 88(11):2494-503. PubMed ID: 20623531
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Wild-type Cu/Zn superoxide dismutase stabilizes mutant variants by heterodimerization.
    Weichert A; Besemer AS; Liebl M; Hellmann N; Koziollek-Drechsler I; Ip P; Decker H; Robertson J; Chakrabartty A; Behl C; Clement AM
    Neurobiol Dis; 2014 Feb; 62():479-88. PubMed ID: 24200866
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Endogenous macrophage migration inhibitory factor reduces the accumulation and toxicity of misfolded SOD1 in a mouse model of ALS.
    Leyton-Jaimes MF; Benaim C; Abu-Hamad S; Kahn J; Guetta A; Bucala R; Israelson A
    Proc Natl Acad Sci U S A; 2016 Sep; 113(36):10198-203. PubMed ID: 27551074
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A mechanism for propagated SOD1 misfolding from frustration analysis of a G85R mutant protein assembly.
    Healy EF
    Biochem Biophys Res Commun; 2016 Sep; 478(4):1634-9. PubMed ID: 27591900
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.