BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 21932445)

  • 1. Dose-dependent proteomic analysis of glioblastoma cancer stem cells upon treatment with γ-secretase inhibitor.
    Dai L; He J; Liu Y; Byun J; Vivekanandan A; Pennathur S; Fan X; Lubman DM
    Proteomics; 2011 Dec; 11(23):4529-40. PubMed ID: 21932445
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts.
    Fan X; Khaki L; Zhu TS; Soules ME; Talsma CE; Gul N; Koh C; Zhang J; Li YM; Maciaczyk J; Nikkhah G; Dimeco F; Piccirillo S; Vescovi AL; Eberhart CG
    Stem Cells; 2010 Jan; 28(1):5-16. PubMed ID: 19904829
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alpha-secretase inhibition reduces human glioblastoma stem cell growth in vitro and in vivo by inhibiting Notch.
    Floyd DH; Kefas B; Seleverstov O; Mykhaylyk O; Dominguez C; Comeau L; Plank C; Purow B
    Neuro Oncol; 2012 Oct; 14(10):1215-26. PubMed ID: 22962413
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential profiling studies of N-linked glycoproteins in glioblastoma cancer stem cells upon treatment with γ-secretase inhibitor.
    Dai L; Liu Y; He J; Flack CG; Talsma CE; Crowley JG; Muraszko KM; Fan X; Lubman DM
    Proteomics; 2011 Oct; 11(20):4021-8. PubMed ID: 21898824
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A high Notch pathway activation predicts response to γ secretase inhibitors in proneural subtype of glioma tumor-initiating cells.
    Saito N; Fu J; Zheng S; Yao J; Wang S; Liu DD; Yuan Y; Sulman EP; Lang FF; Colman H; Verhaak RG; Yung WK; Koul D
    Stem Cells; 2014 Jan; 32(1):301-12. PubMed ID: 24038660
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gamma-Secretase Inhibitor IX (GSI) Impairs Concomitant Activation of Notch and Wnt-Beta-Catenin Pathways in CD44
    Barat S; Chen X; Cuong Bui K; Bozko P; Götze J; Christgen M; Krech T; Malek NP; Plentz RR
    Stem Cells Transl Med; 2017 Mar; 6(3):819-829. PubMed ID: 28186678
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting cancer stem cells in glioblastoma multiforme using mTOR inhibitors and the differentiating agent all-trans retinoic acid.
    Friedman MD; Jeevan DS; Tobias M; Murali R; Jhanwar-Uniyal M
    Oncol Rep; 2013 Oct; 30(4):1645-50. PubMed ID: 23877261
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Blocking the NOTCH pathway can inhibit the growth of CD133-positive A549 cells and sensitize to chemotherapy.
    Liu J; Mao Z; Huang J; Xie S; Liu T; Mao Z
    Biochem Biophys Res Commun; 2014 Feb; 444(4):670-5. PubMed ID: 24502949
    [TBL] [Abstract][Full Text] [Related]  

  • 9. γ-Secretase inhibitor-resistant glioblastoma stem cells require RBPJ to propagate.
    Fan X
    J Clin Invest; 2016 Jul; 126(7):2415-8. PubMed ID: 27322058
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of Notch signaling alters the phenotype of orthotopic tumors formed from glioblastoma multiforme neurosphere cells but does not hamper intracranial tumor growth regardless of endogene Notch pathway signature.
    Kristoffersen K; Nedergaard MK; Villingshøj M; Borup R; Broholm H; Kjær A; Poulsen HS; Stockhausen MT
    Cancer Biol Ther; 2014 Jul; 15(7):862-77. PubMed ID: 24755988
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Unlocking the Secrets of Cancer Stem Cells with γ-Secretase Inhibitors: A Novel Anticancer Strategy.
    Ghanbari-Movahed M; Ghanbari-Movahed Z; Momtaz S; Kilpatrick KL; Farzaei MH; Bishayee A
    Molecules; 2021 Feb; 26(4):. PubMed ID: 33673088
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting atypical protein kinase C iota reduces viability in glioblastoma stem-like cells via a notch signaling mechanism.
    Phillips E; Lang V; Bohlen J; Bethke F; Puccio L; Tichy D; Herold-Mende C; Hielscher T; Lichter P; Goidts V
    Int J Cancer; 2016 Oct; 139(8):1776-87. PubMed ID: 27299852
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gamma-secretase inhibitors enhance temozolomide treatment of human gliomas by inhibiting neurosphere repopulation and xenograft recurrence.
    Gilbert CA; Daou MC; Moser RP; Ross AH
    Cancer Res; 2010 Sep; 70(17):6870-9. PubMed ID: 20736377
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Level of Notch activation determines the effect on growth and stem cell-like features in glioblastoma multiforme neurosphere cultures.
    Kristoffersen K; Villingshøj M; Poulsen HS; Stockhausen MT
    Cancer Biol Ther; 2013 Jul; 14(7):625-37. PubMed ID: 23792644
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of A1 and A2B adenosine receptor activity: a new strategy to sensitise glioblastoma stem cells to chemotherapy.
    Daniele S; Zappelli E; Natali L; Martini C; Trincavelli ML
    Cell Death Dis; 2014 Nov; 5(11):e1539. PubMed ID: 25429616
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transforming growth factor-β mimics the key proteome properties of CD133
    Bryukhovetskiy I; Shevchenko V; Arnotskaya N; Kushnir T; Pak O; Victor Z; Zaitsev S; Khotimchenko Y; Bryukhovetskiy A; Sharma A; Sharma HS
    Int Rev Neurobiol; 2020; 151():219-242. PubMed ID: 32448609
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proteins of the Wnt signaling pathway as targets for the regulation of CD133+ cancer stem cells in glioblastoma.
    Shevchenko V; Arnotskaya N; Korneyko M; Zaytsev S; Khotimchenko Y; Sharma H; Bryukhovetskiy I
    Oncol Rep; 2019 May; 41(5):3080-3088. PubMed ID: 30864699
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6-Abundant Breast Cancer Cells by Regulating γ-Secretase-Mediated Notch1 Activation in Caveolae.
    Hsu EC; Kulp SK; Huang HL; Tu HJ; Salunke SB; Sullivan NJ; Sun D; Wicha MS; Shapiro CL; Chen CS
    Neoplasia; 2015 Jun; 17(6):497-508. PubMed ID: 26152358
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting Notch signaling by γ-secretase inhibitor I enhances the cytotoxic effect of 5-FU in gastric cancer.
    Lee HW; Kim SJ; Choi IJ; Song J; Chun KH
    Clin Exp Metastasis; 2015 Aug; 32(6):593-603. PubMed ID: 26134677
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures.
    Carra E; Barbieri F; Marubbi D; Pattarozzi A; Favoni RE; Florio T; Daga A
    Cell Cycle; 2013 Feb; 12(3):491-500. PubMed ID: 23324350
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.