277 related articles for article (PubMed ID: 21934106)
1. A synthetic biology approach reveals a CXCR4-G13-Rho signaling axis driving transendothelial migration of metastatic breast cancer cells.
Yagi H; Tan W; Dillenburg-Pilla P; Armando S; Amornphimoltham P; Simaan M; Weigert R; Molinolo AA; Bouvier M; Gutkind JS
Sci Signal; 2011 Sep; 4(191):ra60. PubMed ID: 21934106
[TBL] [Abstract][Full Text] [Related]
2. The Galpha13-Rho signaling axis is required for SDF-1-induced migration through CXCR4.
Tan W; Martin D; Gutkind JS
J Biol Chem; 2006 Dec; 281(51):39542-9. PubMed ID: 17056591
[TBL] [Abstract][Full Text] [Related]
3. Agonist-induced CXCR4 and CB2 Heterodimerization Inhibits Gα13/RhoA-mediated Migration.
Scarlett KA; White EZ; Coke CJ; Carter JR; Bryant LK; Hinton CV
Mol Cancer Res; 2018 Apr; 16(4):728-739. PubMed ID: 29330286
[TBL] [Abstract][Full Text] [Related]
4. G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase.
Takashima S; Sugimoto N; Takuwa N; Okamoto Y; Yoshioka K; Takamura M; Takata S; Kaneko S; Takuwa Y
Cardiovasc Res; 2008 Sep; 79(4):689-97. PubMed ID: 18480127
[TBL] [Abstract][Full Text] [Related]
5. SDF-1/CXCL12 induces directional cell migration and spontaneous metastasis via a CXCR4/Gαi/mTORC1 axis.
Dillenburg-Pilla P; Patel V; Mikelis CM; Zárate-Bladés CR; Doçi CL; Amornphimoltham P; Wang Z; Martin D; Leelahavanichkul K; Dorsam RT; Masedunskas A; Weigert R; Molinolo AA; Gutkind JS
FASEB J; 2015 Mar; 29(3):1056-68. PubMed ID: 25466898
[TBL] [Abstract][Full Text] [Related]
6. Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells.
Yi T; Zhai B; Yu Y; Kiyotsugu Y; Raschle T; Etzkorn M; Seo HC; Nagiec M; Luna RE; Reinherz EL; Blenis J; Gygi SP; Wagner G
Proc Natl Acad Sci U S A; 2014 May; 111(21):E2182-90. PubMed ID: 24782546
[TBL] [Abstract][Full Text] [Related]
7. Breast cancer metastasis: demonstration that FOXP3 regulates CXCR4 expression and the response to CXCL12.
Douglass S; Meeson AP; Overbeck-Zubrzycka D; Brain JG; Bennett MR; Lamb CA; Lennard TW; Browell D; Ali S; Kirby JA
J Pathol; 2014 Sep; 234(1):74-85. PubMed ID: 24870556
[TBL] [Abstract][Full Text] [Related]
8. Downregulation of CXCR4 by SDF-KDEL in SBC-5 cells inhibits their migration in vitro and organ metastasis in vivo.
Ma N; Pang H; Shen W; Zhang F; Cui Z; Wang J; Wang J; Liu L; Zhang H
Int J Mol Med; 2015 Feb; 35(2):425-32. PubMed ID: 25504108
[TBL] [Abstract][Full Text] [Related]
9. Differential functional activation of chemokine receptor CXCR4 is mediated by G proteins in breast cancer cells.
Holland JD; Kochetkova M; Akekawatchai C; Dottore M; Lopez A; McColl SR
Cancer Res; 2006 Apr; 66(8):4117-24. PubMed ID: 16618732
[TBL] [Abstract][Full Text] [Related]
10. LRRC4 inhibits human glioblastoma cells proliferation, invasion, and proMMP-2 activation by reducing SDF-1 alpha/CXCR4-mediated ERK1/2 and Akt signaling pathways.
Wu M; Chen Q; Li D; Li X; Li X; Huang C; Tang Y; Zhou Y; Wang D; Tang K; Cao L; Shen S; Li G
J Cell Biochem; 2008 Jan; 103(1):245-55. PubMed ID: 17549698
[TBL] [Abstract][Full Text] [Related]
11. Phenotypic Knockout of CXCR4 Expression by a Novel Intrakine Mutant hSDF-1α/54/KDEL Inhibits Breast Cancer Metastasis.
Chen HY; Clayman ES; Ma WF
J Interferon Cytokine Res; 2015 Oct; 35(10):771-8. PubMed ID: 25978539
[TBL] [Abstract][Full Text] [Related]
12. Involvement of the chemokine receptor CXCR4 and its ligand stromal cell-derived factor 1alpha in breast cancer cell migration through human brain microvascular endothelial cells.
Lee BC; Lee TH; Avraham S; Avraham HK
Mol Cancer Res; 2004 Jun; 2(6):327-38. PubMed ID: 15235108
[TBL] [Abstract][Full Text] [Related]
13. New insight into the SDF-1/CXCR4 axis in a breast carcinoma model: hypoxia-induced endothelial SDF-1 and tumor cell CXCR4 are required for tumor cell intravasation.
Jin F; Brockmeier U; Otterbach F; Metzen E
Mol Cancer Res; 2012 Aug; 10(8):1021-31. PubMed ID: 22767589
[TBL] [Abstract][Full Text] [Related]
14. AGTR1 promotes lymph node metastasis in breast cancer by upregulating CXCR4/SDF-1α and inducing cell migration and invasion.
Ma Y; Xia Z; Ye C; Lu C; Zhou S; Pan J; Liu C; Zhang J; Liu T; Hu T; Xie L; Wu G; Zhao Y
Aging (Albany NY); 2019 Jun; 11(12):3969-3992. PubMed ID: 31219799
[TBL] [Abstract][Full Text] [Related]
15. Involvement of chemokine receptors in breast cancer metastasis.
Müller A; Homey B; Soto H; Ge N; Catron D; Buchanan ME; McClanahan T; Murphy E; Yuan W; Wagner SN; Barrera JL; Mohar A; Verástegui E; Zlotnik A
Nature; 2001 Mar; 410(6824):50-6. PubMed ID: 11242036
[TBL] [Abstract][Full Text] [Related]
16. Krüppel-like factor 8 activates the transcription of C-X-C cytokine receptor type 4 to promote breast cancer cell invasion, transendothelial migration and metastasis.
Mukherjee D; Lu H; Yu L; He C; Lahiri SK; Li T; Zhao J
Oncotarget; 2016 Apr; 7(17):23552-68. PubMed ID: 26993780
[TBL] [Abstract][Full Text] [Related]
17. CXCR4-Targeted and Redox Responsive Dextrin Nanogel for Metastatic Breast Cancer Therapy.
Zhang F; Gong S; Wu J; Li H; Oupicky D; Sun M
Biomacromolecules; 2017 Jun; 18(6):1793-1802. PubMed ID: 28445650
[TBL] [Abstract][Full Text] [Related]
18. Gα13 and Rho mediate endosomal trafficking of CXCR4 into Rab11+ vesicles upon stromal cell-derived factor-1 stimulation.
Kumar A; Kremer KN; Dominguez D; Tadi M; Hedin KE
J Immunol; 2011 Jan; 186(2):951-8. PubMed ID: 21148034
[TBL] [Abstract][Full Text] [Related]
19. The CXCL12-CXCR4 chemokine pathway: a novel axis regulates lymphangiogenesis.
Zhuo W; Jia L; Song N; Lu XA; Ding Y; Wang X; Song X; Fu Y; Luo Y
Clin Cancer Res; 2012 Oct; 18(19):5387-98. PubMed ID: 22932666
[TBL] [Abstract][Full Text] [Related]
20. Inflammatory CXCL12-CXCR4/CXCR7 axis mediates G-protein signaling pathway to influence the invasion and migration of nasopharyngeal carcinoma cells.
Qiao N; Wang L; Wang T; Li H
Tumour Biol; 2016 Jun; 37(6):8169-79. PubMed ID: 26715277
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]