484 related articles for article (PubMed ID: 21937428)
1. Alsin and SOD1(G93A) proteins regulate endosomal reactive oxygen species production by glial cells and proinflammatory pathways responsible for neurotoxicity.
Li Q; Spencer NY; Pantazis NJ; Engelhardt JF
J Biol Chem; 2011 Nov; 286(46):40151-62. PubMed ID: 21937428
[TBL] [Abstract][Full Text] [Related]
2. The NADPH oxidase pathway is dysregulated by the P2X7 receptor in the SOD1-G93A microglia model of amyotrophic lateral sclerosis.
Apolloni S; Parisi C; Pesaresi MG; Rossi S; Carrì MT; Cozzolino M; Volonté C; D'Ambrosi N
J Immunol; 2013 May; 190(10):5187-95. PubMed ID: 23589615
[TBL] [Abstract][Full Text] [Related]
3. Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent.
Aoyama T; Paik YH; Watanabe S; Laleu B; Gaggini F; Fioraso-Cartier L; Molango S; Heitz F; Merlot C; Szyndralewiez C; Page P; Brenner DA
Hepatology; 2012 Dec; 56(6):2316-27. PubMed ID: 22806357
[TBL] [Abstract][Full Text] [Related]
4. SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model.
Harraz MM; Marden JJ; Zhou W; Zhang Y; Williams A; Sharov VS; Nelson K; Luo M; Paulson H; Schöneich C; Engelhardt JF
J Clin Invest; 2008 Feb; 118(2):659-70. PubMed ID: 18219391
[TBL] [Abstract][Full Text] [Related]
5. Expression of amyotrophic lateral sclerosis-linked SOD1 mutant increases the neurotoxic potential of microglia via TLR2.
Liu Y; Hao W; Dawson A; Liu S; Fassbender K
J Biol Chem; 2009 Feb; 284(6):3691-9. PubMed ID: 19091752
[TBL] [Abstract][Full Text] [Related]
6. Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase.
Chéret C; Gervais A; Lelli A; Colin C; Amar L; Ravassard P; Mallet J; Cumano A; Krause KH; Mallat M
J Neurosci; 2008 Nov; 28(46):12039-51. PubMed ID: 19005069
[TBL] [Abstract][Full Text] [Related]
7. Redox modifier genes in amyotrophic lateral sclerosis in mice.
Marden JJ; Harraz MM; Williams AJ; Nelson K; Luo M; Paulson H; Engelhardt JF
J Clin Invest; 2007 Oct; 117(10):2913-9. PubMed ID: 17853944
[TBL] [Abstract][Full Text] [Related]
8. Macrophage-mediated inflammation and glial response in the skeletal muscle of a rat model of familial amyotrophic lateral sclerosis (ALS).
Van Dyke JM; Smit-Oistad IM; Macrander C; Krakora D; Meyer MG; Suzuki M
Exp Neurol; 2016 Mar; 277():275-282. PubMed ID: 26775178
[TBL] [Abstract][Full Text] [Related]
9. Revisiting oxidative damage in ALS: microglia, Nox, and mutant SOD1.
Boillée S; Cleveland DW
J Clin Invest; 2008 Feb; 118(2):474-8. PubMed ID: 18219386
[TBL] [Abstract][Full Text] [Related]
10. Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis.
Seredenina T; Nayernia Z; Sorce S; Maghzal GJ; Filippova A; Ling SC; Basset O; Plastre O; Daali Y; Rushing EJ; Giordana MT; Cleveland DW; Aguzzi A; Stocker R; Krause KH; Jaquet V
Free Radic Biol Med; 2016 Aug; 97():95-108. PubMed ID: 27212019
[TBL] [Abstract][Full Text] [Related]
11. Endosomal Nox2 facilitates redox-dependent induction of NF-kappaB by TNF-alpha.
Li Q; Spencer NY; Oakley FD; Buettner GR; Engelhardt JF
Antioxid Redox Signal; 2009 Jun; 11(6):1249-63. PubMed ID: 19113817
[TBL] [Abstract][Full Text] [Related]
12. Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.
Hadano S; Mitsui S; Pan L; Otomo A; Kubo M; Sato K; Ono S; Onodera W; Abe K; Chen X; Koike M; Uchiyama Y; Aoki M; Warabi E; Yamamoto M; Ishii T; Yanagawa T; Shang HF; Yoshii F
Hum Mol Genet; 2016 Aug; 25(15):3321-3340. PubMed ID: 27439389
[TBL] [Abstract][Full Text] [Related]
13. Reactive Oxygen Species Can Provide Atheroprotection via NOX4-Dependent Inhibition of Inflammation and Vascular Remodeling.
Gray SP; Di Marco E; Kennedy K; Chew P; Okabe J; El-Osta A; Calkin AC; Biessen EA; Touyz RM; Cooper ME; Schmidt HH; Jandeleit-Dahm KA
Arterioscler Thromb Vasc Biol; 2016 Feb; 36(2):295-307. PubMed ID: 26715682
[TBL] [Abstract][Full Text] [Related]
14. TIAM1-RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy.
Kowluru RA; Kowluru A; Veluthakal R; Mohammad G; Syed I; Santos JM; Mishra M
Diabetologia; 2014 May; 57(5):1047-56. PubMed ID: 24554007
[TBL] [Abstract][Full Text] [Related]
15. Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants.
Kanekura K; Hashimoto Y; Niikura T; Aiso S; Matsuoka M; Nishimoto I
J Biol Chem; 2004 Apr; 279(18):19247-56. PubMed ID: 14970233
[TBL] [Abstract][Full Text] [Related]
16. Characterizing the multiple roles of FGF-2 in SOD1
Kefalakes E; Böselt S; Sarikidi A; Ettcheto M; Bursch F; Naujock M; Stanslowsky N; Schmuck M; Barenys M; Wegner F; Grothe C; Petri S
J Cell Physiol; 2019 May; 234(5):7395-7410. PubMed ID: 30370540
[TBL] [Abstract][Full Text] [Related]
17. Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells.
Ferri A; Nencini M; Casciati A; Cozzolino M; Angelini DF; Longone P; Spalloni A; Rotilio G; Carrì MT
FASEB J; 2004 Aug; 18(11):1261-3. PubMed ID: 15208263
[TBL] [Abstract][Full Text] [Related]
18. Different human copper-zinc superoxide dismutase mutants, SOD1G93A and SOD1H46R, exert distinct harmful effects on gross phenotype in mice.
Pan L; Yoshii Y; Otomo A; Ogawa H; Iwasaki Y; Shang HF; Hadano S
PLoS One; 2012; 7(3):e33409. PubMed ID: 22438926
[TBL] [Abstract][Full Text] [Related]
19. Phosphatidylinositol 3-kinase-dependent membrane recruitment of Rac-1 and p47phox is critical for alpha-platelet-derived growth factor receptor-induced production of reactive oxygen species.
Bäumer AT; Ten Freyhaus H; Sauer H; Wartenberg M; Kappert K; Schnabel P; Konkol C; Hescheler J; Vantler M; Rosenkranz S
J Biol Chem; 2008 Mar; 283(12):7864-76. PubMed ID: 18070887
[TBL] [Abstract][Full Text] [Related]
20. Protein disulfide isomerase in ALS mouse glia links protein misfolding with NADPH oxidase-catalyzed superoxide production.
Jaronen M; Vehviläinen P; Malm T; Keksa-Goldsteine V; Pollari E; Valonen P; Koistinaho J; Goldsteins G
Hum Mol Genet; 2013 Feb; 22(4):646-55. PubMed ID: 23118353
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]