186 related articles for article (PubMed ID: 21939233)
21. Enzyme architecture: the effect of replacement and deletion mutations of loop 6 on catalysis by triosephosphate isomerase.
Zhai X; Go MK; O'Donoghue AC; Amyes TL; Pegan SD; Wang Y; Loria JP; Mesecar AD; Richard JP
Biochemistry; 2014 Jun; 53(21):3486-501. PubMed ID: 24825099
[TBL] [Abstract][Full Text] [Related]
22. Anion binding at the active site of trypanosomal triosephosphate isomerase. Monohydrogen phosphate does not mimic sulphate.
Verlinde CL; Noble ME; Kalk KH; Groendijk H; Wierenga RK; Hol WG
Eur J Biochem; 1991 May; 198(1):53-7. PubMed ID: 2040290
[TBL] [Abstract][Full Text] [Related]
23. Enzyme Architecture: Amino Acid Side-Chains That Function To Optimize the Basicity of the Active Site Glutamate of Triosephosphate Isomerase.
Zhai X; Reinhardt CJ; Malabanan MM; Amyes TL; Richard JP
J Am Chem Soc; 2018 Jul; 140(26):8277-8286. PubMed ID: 29862813
[TBL] [Abstract][Full Text] [Related]
24. Magnitude and origin of the enhanced basicity of the catalytic glutamate of triosephosphate isomerase.
Malabanan MM; Nitsch-Velasquez L; Amyes TL; Richard JP
J Am Chem Soc; 2013 Apr; 135(16):5978-81. PubMed ID: 23560625
[TBL] [Abstract][Full Text] [Related]
25. The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
Noble ME; Wierenga RK; Lambeir AM; Opperdoes FR; Thunnissen AM; Kalk KH; Groendijk H; Hol WG
Proteins; 1991; 10(1):50-69. PubMed ID: 2062828
[TBL] [Abstract][Full Text] [Related]
26. Triosephosphate Isomerase: The Crippling Effect of the P168A/I172A Substitution at the Heart of an Enzyme Active Site.
Hegazy R; Richard JP
Biochemistry; 2023 Oct; 62(20):2916-2927. PubMed ID: 37768194
[TBL] [Abstract][Full Text] [Related]
27. Evaluating the catalytic importance of a conserved Glu97 residue in triosephosphate isomerase.
Chang TC; Park JH; Colquhoun AN; Khoury CB; Seangmany NA; Schwans JP
Biochem Biophys Res Commun; 2018 Oct; 505(2):492-497. PubMed ID: 30268499
[TBL] [Abstract][Full Text] [Related]
28. Mechanistic Imperatives for Deprotonation of Carbon Catalyzed by Triosephosphate Isomerase: Enzyme-Activation by Phosphite Dianion.
Zhai X; Malabanan MM; Amyes TL; Richard JP
J Phys Org Chem; 2014 Apr; 27(4):269-276. PubMed ID: 24729658
[TBL] [Abstract][Full Text] [Related]
29. Hydron transfer catalyzed by triosephosphate isomerase. Products of isomerization of (R)-glyceraldehyde 3-phosphate in D2O.
O'Donoghue AC; Amyes TL; Richard JP
Biochemistry; 2005 Feb; 44(7):2610-21. PubMed ID: 15709774
[TBL] [Abstract][Full Text] [Related]
30. Functional role of the conserved active site proline of triosephosphate isomerase.
Casteleijn MG; Alahuhta M; Groebel K; El-Sayed I; Augustyns K; Lambeir AM; Neubauer P; Wierenga RK
Biochemistry; 2006 Dec; 45(51):15483-94. PubMed ID: 17176070
[TBL] [Abstract][Full Text] [Related]
31. Revisiting the mechanism of the triosephosphate isomerase reaction: the role of the fully conserved glutamic acid 97 residue.
Samanta M; Murthy MR; Balaram H; Balaram P
Chembiochem; 2011 Aug; 12(12):1886-96. PubMed ID: 21671330
[TBL] [Abstract][Full Text] [Related]
32. Crystal structure of recombinant human triosephosphate isomerase at 2.8 A resolution. Triosephosphate isomerase-related human genetic disorders and comparison with the trypanosomal enzyme.
Mande SC; Mainfroid V; Kalk KH; Goraj K; Martial JA; Hol WG
Protein Sci; 1994 May; 3(5):810-21. PubMed ID: 8061610
[TBL] [Abstract][Full Text] [Related]
33. Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase.
Salin M; Kapetaniou EG; Vaismaa M; Lajunen M; Casteleijn MG; Neubauer P; Salmon L; Wierenga RK
Acta Crystallogr D Biol Crystallogr; 2010 Aug; 66(Pt 8):934-44. PubMed ID: 20693693
[TBL] [Abstract][Full Text] [Related]
34. Structure of the complex between trypanosomal triosephosphate isomerase and N-hydroxy-4-phosphono-butanamide: binding at the active site despite an "open" flexible loop conformation.
Verlinde CL; Witmans CJ; Pijning T; Kalk KH; Hol WG; Callens M; Opperdoes FR
Protein Sci; 1992 Dec; 1(12):1578-84. PubMed ID: 1304889
[TBL] [Abstract][Full Text] [Related]
35. NMR studies of the role of hydrogen bonding in the mechanism of triosephosphate isomerase.
Harris TK; Abeygunawardana C; Mildvan AS
Biochemistry; 1997 Dec; 36(48):14661-75. PubMed ID: 9398185
[TBL] [Abstract][Full Text] [Related]
36. The critical role of the loops of triosephosphate isomerase for its oligomerization, dynamics, and functionality.
Katebi AR; Jernigan RL
Protein Sci; 2014 Feb; 23(2):213-28. PubMed ID: 24318986
[TBL] [Abstract][Full Text] [Related]
37. Structures of Plasmodium falciparum triosephosphate isomerase complexed to substrate analogues: observation of the catalytic loop in the open conformation in the ligand-bound state.
Parthasarathy S; Balaram H; Balaram P; Murthy MR
Acta Crystallogr D Biol Crystallogr; 2002 Dec; 58(Pt 12):1992-2000. PubMed ID: 12454456
[TBL] [Abstract][Full Text] [Related]
38. Proton transfer in the mechanism of triosephosphate isomerase.
Harris TK; Cole RN; Comer FI; Mildvan AS
Biochemistry; 1998 Nov; 37(47):16828-38. PubMed ID: 9843453
[TBL] [Abstract][Full Text] [Related]
39. Structure of the Plasmodium falciparum triosephosphate isomerase-phosphoglycolate complex in two crystal forms: characterization of catalytic loop open and closed conformations in the ligand-bound state.
Parthasarathy S; Ravindra G; Balaram H; Balaram P; Murthy MR
Biochemistry; 2002 Nov; 41(44):13178-88. PubMed ID: 12403619
[TBL] [Abstract][Full Text] [Related]
40. Computational modeling of the catalytic reaction in triosephosphate isomerase.
Guallar V; Jacobson M; McDermott A; Friesner RA
J Mol Biol; 2004 Mar; 337(1):227-39. PubMed ID: 15001364
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
