490 related articles for article (PubMed ID: 21940714)
1. Development of homogeneous nonradioactive methyltransferase and demethylase assays targeting histone H3 lysine 4.
Gauthier N; Caron M; Pedro L; Arcand M; Blouin J; Labonté A; Normand C; Paquet V; Rodenbrock A; Roy M; Rouleau N; Beaudet L; Padrós J; Rodriguez-Suarez R
J Biomol Screen; 2012 Jan; 17(1):49-58. PubMed ID: 21940714
[TBL] [Abstract][Full Text] [Related]
2. High-throughput TR-FRET assays for identifying inhibitors of LSD1 and JMJD2C histone lysine demethylases.
Yu V; Fisch T; Long AM; Tang J; Lee JH; Hierl M; Chen H; Yakowec P; Schwandner R; Emkey R
J Biomol Screen; 2012 Jan; 17(1):27-38. PubMed ID: 21859682
[TBL] [Abstract][Full Text] [Related]
3. The future therapeutic potential of histone demethylases: A critical analysis.
Natoli G; Testa G; De Santa F
Curr Opin Drug Discov Devel; 2009 Sep; 12(5):607-15. PubMed ID: 19736620
[TBL] [Abstract][Full Text] [Related]
4. Cell-based assays to support the profiling of small molecules with histone methyltransferase and demethylase modulatory activity.
Martinez NJ; Simeonov A
Drug Discov Today Technol; 2015 Nov; 18():9-17. PubMed ID: 26723887
[TBL] [Abstract][Full Text] [Related]
5. Screening for compounds that modulate epigenetic regulation of the transcriptome: an overview.
Eglen RM; Reisine T
J Biomol Screen; 2011 Dec; 16(10):1137-52. PubMed ID: 22002420
[TBL] [Abstract][Full Text] [Related]
6. The emerging therapeutic potential of histone methyltransferase and demethylase inhibitors.
Spannhoff A; Hauser AT; Heinke R; Sippl W; Jung M
ChemMedChem; 2009 Oct; 4(10):1568-82. PubMed ID: 19739196
[TBL] [Abstract][Full Text] [Related]
7. Screening for lysine-specific demethylase-1 inhibitors using a label-free high-throughput mass spectrometry assay.
Plant M; Dineen T; Cheng A; Long AM; Chen H; Morgenstern KA
Anal Biochem; 2011 Dec; 419(2):217-27. PubMed ID: 21855527
[TBL] [Abstract][Full Text] [Related]
8. Targeting histone lysine methylation in cancer.
McGrath J; Trojer P
Pharmacol Ther; 2015 Jun; 150():1-22. PubMed ID: 25578037
[TBL] [Abstract][Full Text] [Related]
9. Efficient hit-finding approaches for histone methyltransferases: the key parameters.
Ahrens T; Bergner A; Sheppard D; Hafenbradl D
J Biomol Screen; 2012 Jan; 17(1):85-98. PubMed ID: 21990582
[TBL] [Abstract][Full Text] [Related]
10. Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy.
Morera L; Lübbert M; Jung M
Clin Epigenetics; 2016; 8():57. PubMed ID: 27222667
[TBL] [Abstract][Full Text] [Related]
11. Inhibitors of enzymes catalyzing modifications to histone lysine residues: structure, function and activity.
Lillico R; Stesco N; Khorshid Amhad T; Cortes C; Namaka MP; Lakowski TM
Future Med Chem; 2016 May; 8(8):879-97. PubMed ID: 27173004
[TBL] [Abstract][Full Text] [Related]
12. Oncoepigenomics: making histone lysine methylation count.
Decarlo D; Hadden MK
Eur J Med Chem; 2012 Oct; 56():179-94. PubMed ID: 22975593
[TBL] [Abstract][Full Text] [Related]
13. TR-FRET cellular assays for interrogating posttranslational modifications of histone H3.
Machleidt T; Robers MB; Hermanson SB; Dudek JM; Bi K
J Biomol Screen; 2011 Dec; 16(10):1236-46. PubMed ID: 21972037
[TBL] [Abstract][Full Text] [Related]
14. A cell-based high-throughput screening assay to measure cellular histone h3 lys27 trimethylation with a modified dissociation-enhanced lanthanide fluorescent immunoassay.
Xie W; Ames RS; Li H
J Biomol Screen; 2012 Jan; 17(1):99-107. PubMed ID: 22086723
[TBL] [Abstract][Full Text] [Related]
15. Screening assays for epigenetic targets using native histones as substrates.
Hauser AT; Bissinger EM; Metzger E; Repenning A; Bauer UM; Mai A; Schüle R; Jung M
J Biomol Screen; 2012 Jan; 17(1):18-26. PubMed ID: 21965113
[TBL] [Abstract][Full Text] [Related]
16. Epigenetic cancer therapy: Proof of concept and remaining challenges.
Mund C; Lyko F
Bioessays; 2010 Nov; 32(11):949-57. PubMed ID: 21154865
[TBL] [Abstract][Full Text] [Related]
17. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.
Shi Y; Lan F; Matson C; Mulligan P; Whetstine JR; Cole PA; Casero RA; Shi Y
Cell; 2004 Dec; 119(7):941-53. PubMed ID: 15620353
[TBL] [Abstract][Full Text] [Related]
18. Identification of cell-active lysine specific demethylase 1-selective inhibitors.
Ueda R; Suzuki T; Mino K; Tsumoto H; Nakagawa H; Hasegawa M; Sasaki R; Mizukami T; Miyata N
J Am Chem Soc; 2009 Dec; 131(48):17536-7. PubMed ID: 19950987
[TBL] [Abstract][Full Text] [Related]
19. Heterogeneous Antibody-Based Activity Assay for Lysine Specific Demethylase 1 (LSD1) on a Histone Peptide Substrate.
Schmitt ML; Ladwein KI; Carlino L; Schulz-Fincke J; Willmann D; Metzger E; Schilcher P; Imhof A; Schüle R; Sippl W; Jung M
J Biomol Screen; 2014 Jul; 19(6):973-8. PubMed ID: 24687155
[TBL] [Abstract][Full Text] [Related]
20. Structure and function of histone H3 lysine 9 methyltransferases and demethylases.
Krishnan S; Horowitz S; Trievel RC
Chembiochem; 2011 Jan; 12(2):254-63. PubMed ID: 21243713
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
