BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

673 related articles for article (PubMed ID: 21942864)

  • 1. Membrane disruption and early events in the aggregation of the diabetes related peptide IAPP from a molecular perspective.
    Brender JR; Salamekh S; Ramamoorthy A
    Acc Chem Res; 2012 Mar; 45(3):454-62. PubMed ID: 21942864
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: the case of islet amyloid polypeptide.
    Smith PE; Brender JR; Ramamoorthy A
    J Am Chem Soc; 2009 Apr; 131(12):4470-8. PubMed ID: 19278224
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology.
    Jaikaran ET; Clark A
    Biochim Biophys Acta; 2001 Nov; 1537(3):179-203. PubMed ID: 11731221
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The β-cell assassin: IAPP cytotoxicity.
    Raleigh D; Zhang X; Hastoy B; Clark A
    J Mol Endocrinol; 2017 Oct; 59(3):R121-R140. PubMed ID: 28811318
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity.
    Brender JR; Hartman K; Reid KR; Kennedy RT; Ramamoorthy A
    Biochemistry; 2008 Dec; 47(48):12680-8. PubMed ID: 18989933
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Causative factors for formation of toxic islet amyloid polypeptide oligomer in type 2 diabetes mellitus.
    Jeong HR; An SS
    Clin Interv Aging; 2015; 10():1873-9. PubMed ID: 26604727
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparative molecular dynamics study of human islet amyloid polypeptide (IAPP) and rat IAPP oligomers.
    Liang G; Zhao J; Yu X; Zheng J
    Biochemistry; 2013 Feb; 52(6):1089-100. PubMed ID: 23331123
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The effect of Aβ on IAPP aggregation in the presence of an isolated β-cell membrane.
    Seeliger J; Weise K; Opitz N; Winter R
    J Mol Biol; 2012 Aug; 421(2-3):348-63. PubMed ID: 22321797
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A mechanistic approach for islet amyloid polypeptide aggregation to develop anti-amyloidogenic agents for type-2 diabetes.
    Ahmad E; Ahmad A; Singh S; Arshad M; Khan AH; Khan RH
    Biochimie; 2011 May; 93(5):793-805. PubMed ID: 21215287
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In Vitro Studies of Membrane Permeability Induced by Amyloidogenic Polypeptides Using Large Unilamellar Vesicles.
    Cao P; Raleigh DP
    Methods Mol Biol; 2016; 1345():283-90. PubMed ID: 26453219
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BRICHOS domain of Bri2 inhibits islet amyloid polypeptide (IAPP) fibril formation and toxicity in human beta cells.
    Oskarsson ME; Hermansson E; Wang Y; Welsh N; Presto J; Johansson J; Westermark GT
    Proc Natl Acad Sci U S A; 2018 Mar; 115(12):E2752-E2761. PubMed ID: 29507232
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Investigation of the effects of two major secretory granules components, insulin and zinc, on human-IAPP amyloid aggregation and membrane damage.
    Khemtemourian L; Antoniciello F; Sahoo BR; Decossas M; Lecomte S; Ramamoorthy A
    Chem Phys Lipids; 2021 Jul; 237():105083. PubMed ID: 33887213
    [TBL] [Abstract][Full Text] [Related]  

  • 13. General amyloid inhibitors? A critical examination of the inhibition of IAPP amyloid formation by inositol stereoisomers.
    Wang H; Raleigh DP
    PLoS One; 2014; 9(9):e104023. PubMed ID: 25260075
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Islet amyloid polypeptide in pancreatic islets from type 2 diabetic subjects.
    Tomita T
    Islets; 2012; 4(3):223-32. PubMed ID: 22847497
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Islet amyloid polypeptide: a review of its biology and potential roles in the pathogenesis of diabetes mellitus.
    O'Brien TD; Butler PC; Westermark P; Johnson KH
    Vet Pathol; 1993 Jul; 30(4):317-32. PubMed ID: 8212454
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology.
    Akter R; Cao P; Noor H; Ridgway Z; Tu LH; Wang H; Wong AG; Zhang X; Abedini A; Schmidt AM; Raleigh DP
    J Diabetes Res; 2016; 2016():2798269. PubMed ID: 26649319
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Membrane disordering is not sufficient for membrane permeabilization by islet amyloid polypeptide: studies of IAPP(20-29) fragments.
    Brender JR; Heyl DL; Samisetti S; Kotler SA; Osborne JM; Pesaru RR; Ramamoorthy A
    Phys Chem Chem Phys; 2013 Jun; 15(23):8908-15. PubMed ID: 23493863
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human IAPP amyloidogenic properties and pancreatic β-cell death.
    Fernández MS
    Cell Calcium; 2014 Nov; 56(5):416-27. PubMed ID: 25224501
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular characterization of the hetero-assembly of β-amyloid peptide with islet amyloid polypeptide.
    Yan LM; Velkova A; Kapurniotu A
    Curr Pharm Des; 2014; 20(8):1182-91. PubMed ID: 23713771
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Islet amyloid polypeptide, islet amyloid, and diabetes mellitus.
    Westermark P; Andersson A; Westermark GT
    Physiol Rev; 2011 Jul; 91(3):795-826. PubMed ID: 21742788
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.