BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

312 related articles for article (PubMed ID: 21942922)

  • 1. Sustained overexpression of CYP1A1 and 1B1 and steady accumulation of DNA adducts by low-dose, continuous exposure to benzo[a]pyrene by polymeric implants.
    Jeyabalan J; Vadhanam MV; Ravoori S; Gupta RC
    Chem Res Toxicol; 2011 Nov; 24(11):1937-43. PubMed ID: 21942922
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tissue specific induction of cytochrome P450 (CYP) 1A1 and 1B1 in rat liver and lung following in vitro (tissue slice) and in vivo exposure to benzo(a)pyrene.
    Harrigan JA; McGarrigle BP; Sutter TR; Olson JR
    Toxicol In Vitro; 2006 Jun; 20(4):426-38. PubMed ID: 16198082
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate.
    Uno S; Dalton TP; Dragin N; Curran CP; Derkenne S; Miller ML; Shertzer HG; Gonzalez FJ; Nebert DW
    Mol Pharmacol; 2006 Apr; 69(4):1103-14. PubMed ID: 16377763
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity.
    Galván N; Teske DE; Zhou G; Moorthy B; MacWilliams PS; Czuprynski CJ; Jefcoate CR
    Toxicol Appl Pharmacol; 2005 Feb; 202(3):244-57. PubMed ID: 15667830
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo[a]pyrene.
    Harrigan JA; Vezina CM; McGarrigle BP; Ersing N; Box HC; Maccubbin AE; Olson JR
    Toxicol Sci; 2004 Feb; 77(2):307-14. PubMed ID: 14691214
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Polycyclic aromatic hydrocarbon-inducible DNA adducts: evidence by 32P-postlabeling and use of knockout mice for Ah receptor-independent mechanisms of metabolic activation in vivo.
    Kondraganti SR; Fernandez-Salguero P; Gonzalez FJ; Ramos KS; Jiang W; Moorthy B
    Int J Cancer; 2003 Jan; 103(1):5-11. PubMed ID: 12455047
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tissue distribution of DNA adducts in rats treated by intramammillary injection with dibenzo[a,l]pyrene, 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene.
    Arif JM; Smith WA; Gupta RC
    Mutat Res; 1997 Aug; 378(1-2):31-9. PubMed ID: 9288883
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Induction of CYP1A1 and CYP1B1 and formation of carcinogen-DNA adducts in normal human mammary epithelial cells treated with benzo[a]pyrene.
    Keshava C; Divi RL; Whipkey DL; Frye BL; McCanlies E; Kuo M; Poirier MC; Weston A
    Cancer Lett; 2005 Apr; 221(2):213-24. PubMed ID: 15808407
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sustained induction of cytochrome P4501A1 in human hepatoma cells by co-exposure to benzo[a]pyrene and 7H-dibenzo[c,g]carbazole underlies the synergistic effects on DNA adduct formation.
    Gábelová A; Poláková V; Prochazka G; Kretová M; Poloncová K; Regendová E; Luciaková K; Segerbäck D
    Toxicol Appl Pharmacol; 2013 Aug; 271(1):1-12. PubMed ID: 23639521
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Benzo[a]pyrene-induced toxicity: paradoxical protection in Cyp1a1(-/-) knockout mice having increased hepatic BaP-DNA adduct levels.
    Uno S; Dalton TP; Shertzer HG; Genter MB; Warshawsky D; Talaska G; Nebert DW
    Biochem Biophys Res Commun; 2001 Dec; 289(5):1049-56. PubMed ID: 11741297
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The resveratrol analogue, 2,3',4,5'-tetramethoxystilbene, does not inhibit CYP gene expression, enzyme activity and benzo[a]pyrene-DNA adduct formation in MCF-7 cells exposed to benzo[a]pyrene.
    Einem Lindeman T; Poirier MC; Divi RL
    Mutagenesis; 2011 Sep; 26(5):629-35. PubMed ID: 21669939
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA adduct formation and persistence in rat tissues following exposure to the mammary carcinogen dibenzo[a,l]pyrene.
    Arif JM; Smith WA; Gupta RC
    Carcinogenesis; 1999 Jun; 20(6):1147-50. PubMed ID: 10357803
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genetic polymorphisms in catalase and CYP1B1 determine DNA adduct formation by benzo(a)pyrene ex vivo.
    Schults MA; Chiu RK; Nagle PW; Wilms LC; Kleinjans JC; van Schooten FJ; Godschalk RW
    Mutagenesis; 2013 Mar; 28(2):181-5. PubMed ID: 23325794
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sustained systemic delivery of green tea polyphenols by polymeric implants significantly diminishes benzo[a]pyrene-induced DNA adducts.
    Cao P; Vadhanam MV; Spencer WA; Cai J; Gupta RC
    Chem Res Toxicol; 2011 Jun; 24(6):877-86. PubMed ID: 21574630
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biotransformation of benzo[a]pyrene in Ahr knockout mice is dependent on time and route of exposure.
    Sagredo C; Mollerup S; Cole KJ; Phillips DH; Uppstad H; Øvrebø S
    Chem Res Toxicol; 2009 Mar; 22(3):584-91. PubMed ID: 19216581
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Long-term effects of a standardized complex mixture of urban dust particulate on the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons in human cells in culture.
    Musafia-Jeknic T; Mahadevan B; Pereira C; Baird WM
    Toxicol Sci; 2005 Dec; 88(2):358-66. PubMed ID: 16162842
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dibenzanthracenes and benzochrysenes elicit both genotoxic and nongenotoxic events in rat liver 'stem-like' cells.
    Svihálková-Sindlerová L; Machala M; Pencíková K; Marvanová S; Neca J; Topinka J; Sevastyanova O; Kozubík A; Vondrácek J
    Toxicology; 2007 Mar; 232(1-2):147-59. PubMed ID: 17287060
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An improved fluorometric assay for dosimetry of benzo(a)pyrene diol-epoxide-DNA adducts in smokers' lung: comparisons with total bulky adducts and aryl hydrocarbon hydroxylase activity.
    Alexandrov K; Rojas M; Geneste O; Castegnaro M; Camus AM; Petruzzelli S; Giuntini C; Bartsch H
    Cancer Res; 1992 Nov; 52(22):6248-53. PubMed ID: 1423269
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Competing roles of cytochrome P450 1A1/1B1 and aldo-keto reductase 1A1 in the metabolic activation of (+/-)-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in human bronchoalveolar cell extracts.
    Jiang H; Shen YM; Quinn AM; Penning TM
    Chem Res Toxicol; 2005 Feb; 18(2):365-74. PubMed ID: 15720144
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Maternal intake of quercetin during gestation alters ex vivo benzo[a]pyrene metabolism and DNA adduct formation in adult offspring.
    Vanhees K; van Schooten FJ; Moonen EJ; Maas LM; van Waalwijk van Doorn-Khosrovani SB; Godschalk RW
    Mutagenesis; 2012 Jul; 27(4):445-51. PubMed ID: 22334599
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.