BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 21944747)

  • 21. Stability and flexibility of marginally hydrophobic-segment stalling at the endoplasmic reticulum translocon.
    Kida Y; Ishihara Y; Fujita H; Onishi Y; Sakaguchi M
    Mol Biol Cell; 2016 Mar; 27(6):930-40. PubMed ID: 26823014
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Apratoxin Kills Cells by Direct Blockade of the Sec61 Protein Translocation Channel.
    Paatero AO; Kellosalo J; Dunyak BM; Almaliti J; Gestwicki JE; Gerwick WH; Taunton J; Paavilainen VO
    Cell Chem Biol; 2016 May; 23(5):561-566. PubMed ID: 27203376
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A part of the transmembrane domain of pro-TNF can function as a cleavable signal sequence that generates a biologically active secretory form of TNF.
    Ishisaka R; Sato N; Tanaka K; Takeshige T; Iwata H; Klostergaard J; Utsumi T
    J Biochem; 1999 Aug; 126(2):413-20. PubMed ID: 10423538
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Defining a conformational consensus motif in cotransin-sensitive signal sequences: a proteomic and site-directed mutagenesis study.
    Klein W; Westendorf C; Schmidt A; Conill-Cortés M; Rutz C; Blohs M; Beyermann M; Protze J; Krause G; Krause E; Schülein R
    PLoS One; 2015; 10(3):e0120886. PubMed ID: 25806945
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Structure of the Inhibited State of the Sec Translocon.
    Gérard SF; Hall BS; Zaki AM; Corfield KA; Mayerhofer PU; Costa C; Whelligan DK; Biggin PC; Simmonds RE; Higgins MK
    Mol Cell; 2020 Aug; 79(3):406-415.e7. PubMed ID: 32692975
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Interaction mapping of the Sec61 translocon identifies two Sec61α regions interacting with hydrophobic segments in translocating chains.
    Kida Y; Sakaguchi M
    J Biol Chem; 2018 Nov; 293(44):17050-17060. PubMed ID: 30213864
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Dissecting the physiological role of selective transmembrane-segment retention at the ER translocon.
    Cross BC; High S
    J Cell Sci; 2009 Jun; 122(Pt 11):1768-77. PubMed ID: 19417003
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Targeting of HER/ErbB family proteins using broad spectrum Sec61 inhibitors coibamide A and apratoxin A.
    Kazemi S; Kawaguchi S; Badr CE; Mattos DR; Ruiz-Saenz A; Serrill JD; Moasser MM; Dolan BP; Paavilainen VO; Oishi S; McPhail KL; Ishmael JE
    Biochem Pharmacol; 2021 Jan; 183():114317. PubMed ID: 33152346
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The Ribosome-Sec61 Translocon Complex Forms a Cytosolically Restricted Environment for Early Polytopic Membrane Protein Folding.
    Patterson MA; Bandyopadhyay A; Devaraneni PK; Woodward J; Rooney L; Yang Z; Skach WR
    J Biol Chem; 2015 Nov; 290(48):28944-52. PubMed ID: 26254469
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Proteomics Reveals Scope of Mycolactone-mediated Sec61 Blockade and Distinctive Stress Signature.
    Morel JD; Paatero AO; Wei J; Yewdell JW; Guenin-Macé L; Van Haver D; Impens F; Pietrosemoli N; Paavilainen VO; Demangel C
    Mol Cell Proteomics; 2018 Sep; 17(9):1750-1765. PubMed ID: 29915147
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Orientation of internal signal-anchor sequences at the Sec61 translocon.
    Kocik L; Junne T; Spiess M
    J Mol Biol; 2012 Dec; 424(5):368-78. PubMed ID: 23084973
    [TBL] [Abstract][Full Text] [Related]  

  • 32. TRAM1 protein may support ER protein import by modulating the phospholipid bilayer near the lateral gate of the Sec61-channel.
    Klein MC; Lerner M; Nguyen D; Pfeffer S; Dudek J; Förster F; Helms V; Lang S; Zimmermann R
    Channels (Austin); 2020 Dec; 14(1):28-44. PubMed ID: 32013668
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Coibamide A Targets Sec61 to Prevent Biogenesis of Secretory and Membrane Proteins.
    Tranter D; Paatero AO; Kawaguchi S; Kazemi S; Serrill JD; Kellosalo J; Vogel WK; Richter U; Mattos DR; Wan X; Thornburg CC; Oishi S; McPhail KL; Ishmael JE; Paavilainen VO
    ACS Chem Biol; 2020 Aug; 15(8):2125-2136. PubMed ID: 32608972
    [TBL] [Abstract][Full Text] [Related]  

  • 34. TRC40 can deliver short secretory proteins to the Sec61 translocon.
    Johnson N; Vilardi F; Lang S; Leznicki P; Zimmermann R; High S
    J Cell Sci; 2012 Aug; 125(Pt 15):3612-20. PubMed ID: 22505607
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Sequence-specific retention and regulated integration of a nascent membrane protein by the endoplasmic reticulum Sec61 translocon.
    Pitonzo D; Yang Z; Matsumura Y; Johnson AE; Skach WR
    Mol Biol Cell; 2009 Jan; 20(2):685-98. PubMed ID: 19019984
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon.
    von der Malsburg K; Shao S; Hegde RS
    Mol Biol Cell; 2015 Jun; 26(12):2168-80. PubMed ID: 25877867
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The Sec61 complex is essential for the insertion of proteins into the membrane of the endoplasmic reticulum.
    Oliver J; Jungnickel B; Görlich D; Rapoport T; High S
    FEBS Lett; 1995 Apr; 362(2):126-30. PubMed ID: 7720858
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Recognition of transmembrane helices by the endoplasmic reticulum translocon.
    Hessa T; Kim H; Bihlmaier K; Lundin C; Boekel J; Andersson H; Nilsson I; White SH; von Heijne G
    Nature; 2005 Jan; 433(7024):377-81. PubMed ID: 15674282
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The molecular mechanisms underlying BiP-mediated gating of the Sec61 translocon of the endoplasmic reticulum.
    Alder NN; Shen Y; Brodsky JL; Hendershot LM; Johnson AE
    J Cell Biol; 2005 Jan; 168(3):389-99. PubMed ID: 15684029
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mammalian SRP receptor switches the Sec61 translocase from Sec62 to SRP-dependent translocation.
    Jadhav B; McKenna M; Johnson N; High S; Sinning I; Pool MR
    Nat Commun; 2015 Dec; 6():10133. PubMed ID: 26634806
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.