425 related articles for article (PubMed ID: 21944974)
1. Molecular pathology of MELAS and L-arginine effects.
Koga Y; Povalko N; Nishioka J; Katayama K; Yatsuga S; Matsuishi T
Biochim Biophys Acta; 2012 May; 1820(5):608-14. PubMed ID: 21944974
[TBL] [Abstract][Full Text] [Related]
2. MELAS syndrome: Clinical manifestations, pathogenesis, and treatment options.
El-Hattab AW; Adesina AM; Jones J; Scaglia F
Mol Genet Metab; 2015; 116(1-2):4-12. PubMed ID: 26095523
[TBL] [Abstract][Full Text] [Related]
3. Modification defect at anticodon wobble nucleotide of mitochondrial tRNAs(Leu)(UUR) with pathogenic mutations of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes.
Yasukawa T; Suzuki T; Ueda T; Ohta S; Watanabe K
J Biol Chem; 2000 Feb; 275(6):4251-7. PubMed ID: 10660592
[TBL] [Abstract][Full Text] [Related]
4. MELAS and L-arginine therapy: pathophysiology of stroke-like episodes.
Koga Y; Povalko N; Nishioka J; Katayama K; Kakimoto N; Matsuishi T
Ann N Y Acad Sci; 2010 Jul; 1201():104-10. PubMed ID: 20649546
[TBL] [Abstract][Full Text] [Related]
5. The pathogenic A3243G mutation in human mitochondrial tRNALeu(UUR) decreases the efficiency of aminoacylation.
Park H; Davidson E; King MP
Biochemistry; 2003 Feb; 42(4):958-64. PubMed ID: 12549915
[TBL] [Abstract][Full Text] [Related]
6. Codon-specific translational defect caused by a wobble modification deficiency in mutant tRNA from a human mitochondrial disease.
Kirino Y; Yasukawa T; Ohta S; Akira S; Ishihara K; Watanabe K; Suzuki T
Proc Natl Acad Sci U S A; 2004 Oct; 101(42):15070-5. PubMed ID: 15477592
[TBL] [Abstract][Full Text] [Related]
7. In vivo functional brain imaging and a therapeutic trial of L-arginine in MELAS patients.
Yoneda M; Ikawa M; Arakawa K; Kudo T; Kimura H; Fujibayashi Y; Okazawa H
Biochim Biophys Acta; 2012 May; 1820(5):615-8. PubMed ID: 21600268
[TBL] [Abstract][Full Text] [Related]
8. Human mitochondrial leucyl-tRNA synthetase corrects mitochondrial dysfunctions due to the tRNALeu(UUR) A3243G mutation, associated with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like symptoms and diabetes.
Li R; Guan MX
Mol Cell Biol; 2010 May; 30(9):2147-54. PubMed ID: 20194621
[TBL] [Abstract][Full Text] [Related]
9. Acquisition of the wobble modification in mitochondrial tRNALeu(CUN) bearing the G12300A mutation suppresses the MELAS molecular defect.
Kirino Y; Yasukawa T; Marjavaara SK; Jacobs HT; Holt IJ; Watanabe K; Suzuki T
Hum Mol Genet; 2006 Mar; 15(6):897-904. PubMed ID: 16446307
[TBL] [Abstract][Full Text] [Related]
10. Taurine deficiency and MELAS are closely related syndromes.
Schaffer SW; Jong CJ; Warner D; Ito T; Azuma J
Adv Exp Med Biol; 2013; 776():153-65. PubMed ID: 23392880
[TBL] [Abstract][Full Text] [Related]
11. A mitochondrial tRNA(Leu)(UUR) mutation at 3,256 associated with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS).
Sato W; Hayasaka K; Shoji Y; Takahashi T; Takada G; Saito M; Fukawa O; Wachi E
Biochem Mol Biol Int; 1994 Aug; 33(6):1055-61. PubMed ID: 7804130
[TBL] [Abstract][Full Text] [Related]
12. The mitochondrial myopathy encephalopathy, lactic acidosis with stroke-like episodes (MELAS) syndrome: a review of treatment options.
Scaglia F; Northrop JL
CNS Drugs; 2006; 20(6):443-64. PubMed ID: 16734497
[TBL] [Abstract][Full Text] [Related]
13. L-Arginine Affects Aerobic Capacity and Muscle Metabolism in MELAS (Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-Like Episodes) Syndrome.
Rodan LH; Wells GD; Banks L; Thompson S; Schneiderman JE; Tein I
PLoS One; 2015; 10(5):e0127066. PubMed ID: 25993630
[TBL] [Abstract][Full Text] [Related]
14. [MELAS: Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-Like Episodes].
Murakami H; Ono K
Brain Nerve; 2017 Feb; 69(2):111-117. PubMed ID: 28202819
[TBL] [Abstract][Full Text] [Related]
15. The mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episode syndrome-associated human mitochondrial tRNALeu(UUR) mutation causes aminoacylation deficiency and concomitant reduced association of mRNA with ribosomes.
Chomyn A; Enriquez JA; Micol V; Fernandez-Silva P; Attardi G
J Biol Chem; 2000 Jun; 275(25):19198-209. PubMed ID: 10858457
[TBL] [Abstract][Full Text] [Related]
16. Specific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial disease.
Kirino Y; Goto Y; Campos Y; Arenas J; Suzuki T
Proc Natl Acad Sci U S A; 2005 May; 102(20):7127-32. PubMed ID: 15870203
[TBL] [Abstract][Full Text] [Related]
17. A new point mutation at nucleotide pair 3291 of the mitochondrial tRNA(Leu(UUR)) gene in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS).
Goto Y; Tsugane K; Tanabe Y; Nonaka I; Horai S
Biochem Biophys Res Commun; 1994 Aug; 202(3):1624-30. PubMed ID: 7520241
[TBL] [Abstract][Full Text] [Related]
18. MELAS phenotype associated with m.3302A>G mutation in mitochondrial tRNA(Leu(UUR)) gene.
Goto M; Komaki H; Saito T; Saito Y; Nakagawa E; Sugai K; Sasaki M; Nishino I; Goto Y
Brain Dev; 2014 Feb; 36(2):180-2. PubMed ID: 23582502
[TBL] [Abstract][Full Text] [Related]
19. Reduction of mitochondrial tRNALeu(UUR) aminoacylation by some MELAS-associated mutations.
Hao R; Yao YN; Zheng YG; Xu MG; Wang ED
FEBS Lett; 2004 Dec; 578(1-2):135-9. PubMed ID: 15581630
[TBL] [Abstract][Full Text] [Related]
20. The A3243G tRNALeu(UUR) MELAS mutation causes amino acid misincorporation and a combined respiratory chain assembly defect partially suppressed by overexpression of EFTu and EFG2.
Sasarman F; Antonicka H; Shoubridge EA
Hum Mol Genet; 2008 Dec; 17(23):3697-707. PubMed ID: 18753147
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
