300 related articles for article (PubMed ID: 21945284)
1. Discovery of novel 3,5-disubstituted indole derivatives as potent inhibitors of Pim-1, Pim-2, and Pim-3 protein kinases.
Nishiguchi GA; Atallah G; Bellamacina C; Burger MT; Ding Y; Feucht PH; Garcia PD; Han W; Klivansky L; Lindvall M
Bioorg Med Chem Lett; 2011 Nov; 21(21):6366-9. PubMed ID: 21945284
[TBL] [Abstract][Full Text] [Related]
2. Pim kinase inhibitory and antiproliferative activity of a novel series of meridianin C derivatives.
More KN; Jang HW; Hong VS; Lee J
Bioorg Med Chem Lett; 2014 Jun; 24(11):2424-8. PubMed ID: 24775304
[TBL] [Abstract][Full Text] [Related]
3. Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinases.
Dakin LA; Block MH; Chen H; Code E; Dowling JE; Feng X; Ferguson AD; Green I; Hird AW; Howard T; Keeton EK; Lamb ML; Lyne PD; Pollard H; Read J; Wu AJ; Zhang T; Zheng X
Bioorg Med Chem Lett; 2012 Jul; 22(14):4599-604. PubMed ID: 22727640
[TBL] [Abstract][Full Text] [Related]
4. Discovery and evaluation of 3,5-disubstituted indole derivatives as Pim kinase inhibitors.
More KN; Hong VS; Lee A; Park J; Kim S; Lee J
Bioorg Med Chem Lett; 2018 Aug; 28(14):2513-2517. PubMed ID: 29871845
[TBL] [Abstract][Full Text] [Related]
5. A crystallographic fragment screen identifies cinnamic acid derivatives as starting points for potent Pim-1 inhibitors.
Schulz MN; Fanghänel J; Schäfer M; Badock V; Briem H; Boemer U; Nguyen D; Husemann M; Hillig RC
Acta Crystallogr D Biol Crystallogr; 2011 Mar; 67(Pt 3):156-66. PubMed ID: 21358046
[TBL] [Abstract][Full Text] [Related]
6. The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors.
Wang HL; Cee VJ; Chavez F; Lanman BA; Reed AB; Wu B; Guerrero N; Lipford JR; Sastri C; Winston J; Andrews KL; Huang X; Lee MR; Mohr C; Xu Y; Zhou Y; Tasker AS
Bioorg Med Chem Lett; 2015 Feb; 25(4):834-40. PubMed ID: 25597005
[TBL] [Abstract][Full Text] [Related]
7. Structure and activity relationship of 2-(substituted benzoyl)-hydroxyindoles as novel CaMKII inhibitors.
Komiya M; Asano S; Koike N; Koga E; Igarashi J; Nakatani S; Isobe Y
Bioorg Med Chem Lett; 2011 Mar; 21(5):1456-8. PubMed ID: 21292482
[TBL] [Abstract][Full Text] [Related]
8. Identification and synthesis of N'-(2-oxoindolin-3-ylidene)hydrazide derivatives against c-Met kinase.
Liang Z; Zhang D; Ai J; Chen L; Wang H; Kong X; Zheng M; Liu H; Luo C; Geng M; Jiang H; Chen K
Bioorg Med Chem Lett; 2011 Jun; 21(12):3749-54. PubMed ID: 21561768
[TBL] [Abstract][Full Text] [Related]
9. Discovery of N-substituted 7-azaindoles as Pan-PIM kinase inhibitors - Lead series identification - Part II.
Barberis C; Moorcroft N; Pribish J; Tserlin E; Gross A; Czekaj M; Barrague M; Erdman P; Majid T; Batchelor J; Levit M; Hebert A; Shen L; Moreno-Mazza S; Wang A
Bioorg Med Chem Lett; 2017 Oct; 27(20):4735-4740. PubMed ID: 28927793
[TBL] [Abstract][Full Text] [Related]
10. A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors.
Wang T; Ledeboer MW; Duffy JP; Salituro FG; Pierce AC; Zuccola HJ; Block E; Shlyakter D; Hogan JK; Bennani YL
Bioorg Med Chem Lett; 2010 Jan; 20(1):153-6. PubMed ID: 19945871
[TBL] [Abstract][Full Text] [Related]
11. 3,5-Disubstituted-indole-7-carboxamides: the discovery of a novel series of potent, selective inhibitors of IKK-β.
Miller DD; Bamborough P; Christopher JA; Baldwin IR; Champigny AC; Cutler GJ; Kerns JK; Longstaff T; Mellor GW; Morey JV; Morse MA; Nie H; Rumsey WL; Taggart JJ
Bioorg Med Chem Lett; 2011 Apr; 21(8):2255-8. PubMed ID: 21429745
[TBL] [Abstract][Full Text] [Related]
12. Discovery and optimization of pyrrolo[1,2-a]pyrazinones leads to novel and selective inhibitors of PIM kinases.
Casuscelli F; Ardini E; Avanzi N; Casale E; Cervi G; D'Anello M; Donati D; Faiardi D; Ferguson RD; Fogliatto G; Galvani A; Marsiglio A; Mirizzi DG; Montemartini M; Orrenius C; Papeo G; Piutti C; Salom B; Felder ER
Bioorg Med Chem; 2013 Dec; 21(23):7364-80. PubMed ID: 24139169
[TBL] [Abstract][Full Text] [Related]
13. Structure-aided optimization of kinase inhibitors derived from alsterpaullone.
Kunick C; Zeng Z; Gussio R; Zaharevitz D; Leost M; Totzke F; Schächtele C; Kubbutat MH; Meijer L; Lemcke T
Chembiochem; 2005 Mar; 6(3):541-9. PubMed ID: 15696597
[TBL] [Abstract][Full Text] [Related]
14. Novel potent dual inhibitors of CK2 and Pim kinases with antiproliferative activity against cancer cells.
Pierre F; Regan CF; Chevrel MC; Siddiqui-Jain A; Macalino D; Streiner N; Drygin D; Haddach M; O'Brien SE; Rice WG; Ryckman DM
Bioorg Med Chem Lett; 2012 May; 22(9):3327-31. PubMed ID: 22460033
[TBL] [Abstract][Full Text] [Related]
15. Fragment based discovery of a novel and selective PI3 kinase inhibitor.
Hughes SJ; Millan DS; Kilty IC; Lewthwaite RA; Mathias JP; O'Reilly MA; Pannifer A; Phelan A; Stühmeier F; Baldock DA; Brown DG
Bioorg Med Chem Lett; 2011 Nov; 21(21):6586-90. PubMed ID: 21925880
[TBL] [Abstract][Full Text] [Related]
16. Discovery of a new series of Aurora inhibitors through truncation of GSK1070916.
Medina JR; Grant SW; Axten JM; Miller WH; Donatelli CA; Hardwicke MA; Oleykowski CA; Liao Q; Plant R; Xiang H
Bioorg Med Chem Lett; 2010 Apr; 20(8):2552-5. PubMed ID: 20335034
[TBL] [Abstract][Full Text] [Related]
17. Discovery of imidazo[1,2-a]pyrazine-based Aurora kinase inhibitors.
Belanger DB; Curran PJ; Hruza A; Voigt J; Meng Z; Mandal AK; Siddiqui MA; Basso AD; Gray K
Bioorg Med Chem Lett; 2010 Sep; 20(17):5170-4. PubMed ID: 20674350
[TBL] [Abstract][Full Text] [Related]
18. Structure-based design of 3-aryl-6-amino-triazolo[4,3-b]pyridazine inhibitors of Pim-1 kinase.
Grey R; Pierce AC; Bemis GW; Jacobs MD; Moody CS; Jajoo R; Mohal N; Green J
Bioorg Med Chem Lett; 2009 Jun; 19(11):3019-22. PubMed ID: 19414255
[TBL] [Abstract][Full Text] [Related]
19. Discovery and optimization of a new class of potent and non-chiral indole-3-carboxamide-based renin inhibitors.
Scheiper B; Matter H; Steinhagen H; Stilz U; Böcskei Z; Fleury V; McCort G
Bioorg Med Chem Lett; 2010 Nov; 20(21):6268-72. PubMed ID: 20850300
[TBL] [Abstract][Full Text] [Related]
20. Indole RSK inhibitors. Part 1: discovery and initial SAR.
Boyer SJ; Burke J; Guo X; Kirrane TM; Snow RJ; Zhang Y; Sarko C; Soleymanzadeh L; Swinamer A; Westbrook J; Dicapua F; Padyana A; Cogan D; Gao A; Xiong Z; Madwed JB; Kashem M; Kugler S; O'Neill MM
Bioorg Med Chem Lett; 2012 Jan; 22(1):733-7. PubMed ID: 22100312
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
