263 related articles for article (PubMed ID: 21945397)
41. Inter-conversion of 7alpha- and 7beta-hydroxy-dehydroepiandrosterone by the human 11beta-hydroxysteroid dehydrogenase type 1.
Muller C; Pompon D; Urban P; Morfin R
J Steroid Biochem Mol Biol; 2006 Jun; 99(4-5):215-22. PubMed ID: 16603347
[TBL] [Abstract][Full Text] [Related]
42. 11beta-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP(+) and is stimulated by extracellular glucose.
Dzyakanchuk AA; Balázs Z; Nashev LG; Amrein KE; Odermatt A
Mol Cell Endocrinol; 2009 Mar; 301(1-2):137-41. PubMed ID: 18778749
[TBL] [Abstract][Full Text] [Related]
43. 11β-Hydroxysteroid dehydrogenase type 1 shRNA ameliorates glucocorticoid-induced insulin resistance and lipolysis in mouse abdominal adipose tissue.
Wang Y; Yan C; Liu L; Wang W; Du H; Fan W; Lutfy K; Jiang M; Friedman TC; Liu Y
Am J Physiol Endocrinol Metab; 2015 Jan; 308(1):E84-95. PubMed ID: 25389364
[TBL] [Abstract][Full Text] [Related]
44. Tissue-specific glucocorticoid reactivating enzyme, 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1)--a promising drug target for the treatment of metabolic syndrome.
Masuzaki H; Flier JS
Curr Drug Targets Immune Endocr Metabol Disord; 2003 Dec; 3(4):255-62. PubMed ID: 14683456
[TBL] [Abstract][Full Text] [Related]
45. Hexose-6-phosphate dehydrogenase modulates 11beta-hydroxysteroid dehydrogenase type 1-dependent metabolism of 7-keto- and 7beta-hydroxy-neurosteroids.
Nashev LG; Chandsawangbhuwana C; Balazs Z; Atanasov AG; Dick B; Frey FJ; Baker ME; Odermatt A
PLoS One; 2007 Jun; 2(6):e561. PubMed ID: 17593962
[TBL] [Abstract][Full Text] [Related]
46. 11beta-hydroxysteroid dehydrogenase type 1 as a modulator of glucocorticoid action: from metabolism to memory.
Seckl JR; Walker BR
Trends Endocrinol Metab; 2004 Nov; 15(9):418-24. PubMed ID: 15519888
[TBL] [Abstract][Full Text] [Related]
47. Cell-based assay for screening 11beta-hydroxysteroid dehydrogenase 1 inhibitors.
Cho YS; Kim CH; Cheon HG
Anal Biochem; 2009 Sep; 392(2):110-6. PubMed ID: 19497289
[TBL] [Abstract][Full Text] [Related]
48. 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: a review of recent patents.
Boyle CD; Kowalski TJ
Expert Opin Ther Pat; 2009 Jun; 19(6):801-25. PubMed ID: 19456274
[TBL] [Abstract][Full Text] [Related]
49. Discovery and structure-activity relationships of pentanedioic acid diamides as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
Roche D; Carniato D; Leriche C; Lepifre F; Christmann-Franck S; Graedler U; Charon C; Bozec S; Doare L; Schmidlin F; Lecomte M; Valeur E
Bioorg Med Chem Lett; 2009 May; 19(10):2674-8. PubMed ID: 19395260
[TBL] [Abstract][Full Text] [Related]
50. Antidiabetic effects of 11beta-HSD1 inhibition in a mouse model of combined diabetes, dyslipidaemia and atherosclerosis.
Lloyd DJ; Helmering J; Cordover D; Bowsman M; Chen M; Hale C; Fordstrom P; Zhou M; Wang M; Kaufman SA; Véniant MM
Diabetes Obes Metab; 2009 Jul; 11(7):688-99. PubMed ID: 19527482
[TBL] [Abstract][Full Text] [Related]
51. 7alpha- and 7beta-hydroxy-epiandrosterone as substrates and inhibitors for the human 11beta-hydroxysteroid dehydrogenase type 1.
Hennebert O; Pernelle C; Ferroud C; Morfin R
J Steroid Biochem Mol Biol; 2007; 105(1-5):159-65. PubMed ID: 17624766
[TBL] [Abstract][Full Text] [Related]
52. A novel highly potent and selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, INU-101.
Hong SP; Han D; Chang KH; Ahn SK
Eur J Pharmacol; 2018 Sep; 835():169-178. PubMed ID: 30096297
[TBL] [Abstract][Full Text] [Related]
53. Regulation of 11beta-HSD genes in human adipose tissue: influence of central obesity and weight loss.
Engeli S; Böhnke J; Feldpausch M; Gorzelniak K; Heintze U; Janke J; Luft FC; Sharma AM
Obes Res; 2004 Jan; 12(1):9-17. PubMed ID: 14742837
[TBL] [Abstract][Full Text] [Related]
54. Is the metabolic syndrome an intracellular Cushing state? Effects of multiple humoral factors on the transcriptional activity of the hepatic glucocorticoid-activating enzyme (11beta-hydroxysteroid dehydrogenase type 1) gene.
Iwasaki Y; Takayasu S; Nishiyama M; Tsugita M; Taguchi T; Asai M; Yoshida M; Kambayashi M; Hashimoto K
Mol Cell Endocrinol; 2008 Mar; 285(1-2):10-8. PubMed ID: 18313835
[TBL] [Abstract][Full Text] [Related]
55. A novel 11β-HSD1 inhibitor improves diabesity and osteoblast differentiation.
Park JS; Bae SJ; Choi SW; Son YH; Park SB; Rhee SD; Kim HY; Jung WH; Kang SK; Ahn JH; Kim SH; Kim KY
J Mol Endocrinol; 2014 Apr; 52(2):191-202. PubMed ID: 24444497
[TBL] [Abstract][Full Text] [Related]
56. Identification of a novel 11β-HSD1 inhibitor from a high-throughput screen of natural product extracts.
Park SB; Park JS; Jung WH; Park A; Jo SR; Kim HY; Dal Rhee S; Ryu SY; Jeong HG; Park S; Lee H; Kim KY
Pharmacol Res; 2015 Dec; 102():245-53. PubMed ID: 26515507
[TBL] [Abstract][Full Text] [Related]
57. 2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice.
Johansson L; Fotsch C; Bartberger MD; Castro VM; Chen M; Emery M; Gustafsson S; Hale C; Hickman D; Homan E; Jordan SR; Komorowski R; Li A; McRae K; Moniz G; Matsumoto G; Orihuela C; Palm G; Veniant M; Wang M; Williams M; Zhang J
J Med Chem; 2008 May; 51(10):2933-43. PubMed ID: 18419108
[TBL] [Abstract][Full Text] [Related]
58. Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11β-hydroxysteroid dehydrogenase 1.
Odermatt A; Da Cunha T; Penno CA; Chandsawangbhuwana C; Reichert C; Wolf A; Dong M; Baker ME
Biochem J; 2011 Jun; 436(3):621-9. PubMed ID: 21453287
[TBL] [Abstract][Full Text] [Related]
59. Comparative enzymology of 11beta-hydroxysteroid dehydrogenase type 1 from six species.
Arampatzis S; Kadereit B; Schuster D; Balazs Z; Schweizer RA; Frey FJ; Langer T; Odermatt A
J Mol Endocrinol; 2005 Aug; 35(1):89-101. PubMed ID: 16087724
[TBL] [Abstract][Full Text] [Related]
60. Carbenoxolone treatment attenuates symptoms of metabolic syndrome and atherogenesis in obese, hyperlipidemic mice.
Nuotio-Antar AM; Hachey DL; Hasty AH
Am J Physiol Endocrinol Metab; 2007 Dec; 293(6):E1517-28. PubMed ID: 17878220
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
