158 related articles for article (PubMed ID: 21945530)
1. The rate of polyQ-mediated aggregation is dramatically affected by the number and location of surrounding domains.
Robertson AL; Bate MA; Buckle AM; Bottomley SP
J Mol Biol; 2011 Nov; 413(4):879-87. PubMed ID: 21945530
[TBL] [Abstract][Full Text] [Related]
2. The structural impact of a polyglutamine tract is location-dependent.
Robertson AL; Horne J; Ellisdon AM; Thomas B; Scanlon MJ; Bottomley SP
Biophys J; 2008 Dec; 95(12):5922-30. PubMed ID: 18849414
[TBL] [Abstract][Full Text] [Related]
3. Multi-domain misfolding: understanding the aggregation pathway of polyglutamine proteins.
Saunders HM; Bottomley SP
Protein Eng Des Sel; 2009 Aug; 22(8):447-51. PubMed ID: 19589877
[TBL] [Abstract][Full Text] [Related]
4. Analyzing the aggregation of polyglutamine-expansion proteins and its modulation by molecular chaperones.
Kubota H; Kitamura A; Nagata K
Methods; 2011 Mar; 53(3):267-74. PubMed ID: 21195182
[TBL] [Abstract][Full Text] [Related]
5. PolyQ: a database describing the sequence and domain context of polyglutamine repeats in proteins.
Robertson AL; Bate MA; Androulakis SG; Bottomley SP; Buckle AM
Nucleic Acids Res; 2011 Jan; 39(Database issue):D272-6. PubMed ID: 21059684
[TBL] [Abstract][Full Text] [Related]
6. Polyglutamine expansion mutation yields a pathological epitope linked to nucleation of protein aggregate: determinant of Huntington's disease onset.
Sugaya K; Matsubara S; Kagamihara Y; Kawata A; Hayashi H
PLoS One; 2007 Jul; 2(7):e635. PubMed ID: 17653262
[TBL] [Abstract][Full Text] [Related]
7. Towards the treatment of polyglutamine diseases: the modulatory role of protein context.
Robertson AL; Bottomley SP
Curr Med Chem; 2010; 17(27):3058-68. PubMed ID: 20629626
[TBL] [Abstract][Full Text] [Related]
8. Mimicking proteasomal release of polyglutamine peptides initiates aggregation and toxicity.
Raspe M; Gillis J; Krol H; Krom S; Bosch K; van Veen H; Reits E
J Cell Sci; 2009 Sep; 122(Pt 18):3262-71. PubMed ID: 19690053
[TBL] [Abstract][Full Text] [Related]
9. Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.
Chan WM; Tsoi H; Wu CC; Wong CH; Cheng TC; Li HY; Lau KF; Shaw PC; Perrimon N; Chan HY
Hum Mol Genet; 2011 May; 20(9):1738-50. PubMed ID: 21300695
[TBL] [Abstract][Full Text] [Related]
10. Monitoring polyglutamine toxicity in yeast.
Duennwald ML
Methods; 2011 Mar; 53(3):232-7. PubMed ID: 21144902
[TBL] [Abstract][Full Text] [Related]
11. Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity.
Sakahira H; Breuer P; Hayer-Hartl MK; Hartl FU
Proc Natl Acad Sci U S A; 2002 Dec; 99 Suppl 4(Suppl 4):16412-8. PubMed ID: 12189209
[TBL] [Abstract][Full Text] [Related]
12. Polyglutamine induced misfolding of huntingtin exon1 is modulated by the flanking sequences.
Lakhani VV; Ding F; Dokholyan NV
PLoS Comput Biol; 2010 Apr; 6(4):e1000772. PubMed ID: 20442863
[TBL] [Abstract][Full Text] [Related]
13. Disruption of the toxic conformation of the expanded polyglutamine stretch leads to suppression of aggregate formation and cytotoxicity.
Popiel HA; Nagai Y; Onodera O; Inui T; Fujikake N; Urade Y; Strittmatter WJ; Burke JR; Ichikawa A; Toda T
Biochem Biophys Res Commun; 2004 May; 317(4):1200-6. PubMed ID: 15094397
[TBL] [Abstract][Full Text] [Related]
14. The interplay between PolyQ and protein context delays aggregation by forming a reservoir of protofibrils.
Bulone D; Masino L; Thomas DJ; San Biagio PL; Pastore A
PLoS One; 2006 Dec; 1(1):e111. PubMed ID: 17205115
[TBL] [Abstract][Full Text] [Related]
15. PolyQ fibrillation in the cell nucleus: who's bad?
von Mikecz A
Trends Cell Biol; 2009 Dec; 19(12):685-91. PubMed ID: 19796946
[TBL] [Abstract][Full Text] [Related]
16. Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation.
Sorolla MA; Nierga C; Rodríguez-Colman MJ; Reverter-Branchat G; Arenas A; Tamarit J; Ros J; Cabiscol E
Arch Biochem Biophys; 2011 Jun; 510(1):27-34. PubMed ID: 21513696
[TBL] [Abstract][Full Text] [Related]
17. Polyglutamine homopolymers having 8-45 residues form slablike beta-crystallite assemblies.
Sharma D; Shinchuk LM; Inouye H; Wetzel R; Kirschner DA
Proteins; 2005 Nov; 61(2):398-411. PubMed ID: 16114051
[TBL] [Abstract][Full Text] [Related]
18. Amyloid-like fibril formation by polyQ proteins: a critical balance between the polyQ length and the constraints imposed by the host protein.
Scarafone N; Pain C; Fratamico A; Gaspard G; Yilmaz N; Filée P; Galleni M; Matagne A; Dumoulin M
PLoS One; 2012; 7(3):e31253. PubMed ID: 22438863
[TBL] [Abstract][Full Text] [Related]
19. Effects of chain length on the aggregation of model polyglutamine peptides: molecular dynamics simulations.
Marchut AJ; Hall CK
Proteins; 2007 Jan; 66(1):96-109. PubMed ID: 17068817
[TBL] [Abstract][Full Text] [Related]
20. Folding of polyglutamine chains.
Chopra M; Reddy AS; Abbott NL; de Pablo JJ
J Chem Phys; 2008 Oct; 129(13):135102. PubMed ID: 19045125
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
