131 related articles for article (PubMed ID: 21945929)
21. Downregulation of GLP-1 and GIP receptor expression by hyperglycemia: possible contribution to impaired incretin effects in diabetes.
Xu G; Kaneto H; Laybutt DR; Duvivier-Kali VF; Trivedi N; Suzuma K; King GL; Weir GC; Bonner-Weir S
Diabetes; 2007 Jun; 56(6):1551-8. PubMed ID: 17360984
[TBL] [Abstract][Full Text] [Related]
22. Glucagon like peptide-1-induced glucose metabolism in differentiated human muscle satellite cells is attenuated by hyperglycemia.
Green CJ; Henriksen TI; Pedersen BK; Solomon TP
PLoS One; 2012; 7(8):e44284. PubMed ID: 22937169
[TBL] [Abstract][Full Text] [Related]
23. CCR2 knockout exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased GLP-1 receptor expression and insulin secretion.
Nakamura Y; Kanai T; Saeki K; Takabe M; Irie J; Miyoshi J; Mikami Y; Teratani T; Suzuki T; Miyata N; Hisamatsu T; Nakamoto N; Yamagishi Y; Higuchi H; Ebinuma H; Hozawa S; Saito H; Itoh H; Hibi T
Am J Physiol Gastrointest Liver Physiol; 2013 Apr; 304(8):G700-7. PubMed ID: 23449669
[TBL] [Abstract][Full Text] [Related]
24. Potentiation of insulin secretion and improvement of glucose intolerance by combining a novel G protein-coupled receptor 40 agonist DS-1558 with glucagon-like peptide-1 receptor agonists.
Nakashima R; Yano T; Ogawa J; Tanaka N; Toda N; Yoshida M; Takano R; Inoue M; Honda T; Kume S; Matsumoto K
Eur J Pharmacol; 2014 Aug; 737():194-201. PubMed ID: 24858371
[TBL] [Abstract][Full Text] [Related]
25. Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1.
Delmeire D; Flamez D; Hinke SA; Cali JJ; Pipeleers D; Schuit F
Diabetologia; 2003 Oct; 46(10):1383-93. PubMed ID: 13680124
[TBL] [Abstract][Full Text] [Related]
26. Hyperglycemia induces NF-κB activation and MCP-1 expression via downregulating GLP-1R expression in rat mesangial cells: inhibition by metformin.
Kang Z; Zeng J; Zhang T; Lin S; Gao J; Jiang C; Fan R; Yin D
Cell Biol Int; 2019 Aug; 43(8):940-953. PubMed ID: 31136032
[TBL] [Abstract][Full Text] [Related]
27. Differential protective effects of exenatide, an agonist of GLP-1 receptor and Piragliatin, a glucokinase activator in beta cell response to streptozotocin-induced and endoplasmic reticulum stresses.
Kim MK; Cho JH; Lee JJ; Cheong YH; Son MH; Lee KJ
PLoS One; 2013; 8(9):e73340. PubMed ID: 24069189
[TBL] [Abstract][Full Text] [Related]
28. Chronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic β-cells via protein kinase A.
Rajan S; Dickson LM; Mathew E; Orr CM; Ellenbroek JH; Philipson LH; Wicksteed B
Mol Metab; 2015 Apr; 4(4):265-76. PubMed ID: 25830090
[TBL] [Abstract][Full Text] [Related]
29. The multifaceted potential of glucagon-like peptide-1 as a therapeutic agent.
Lam NT; Kieffer TJ
Minerva Endocrinol; 2002 Jun; 27(2):79-93. PubMed ID: 11961501
[TBL] [Abstract][Full Text] [Related]
30. Homologous desensitization of the insulinotropic glucagon-like peptide-I (7-37) receptor on insulinoma (HIT-T15) cells.
Fehmann HC; Habener JF
Endocrinology; 1991 Jun; 128(6):2880-8. PubMed ID: 1645253
[TBL] [Abstract][Full Text] [Related]
31. Exendin-4 protects bone marrow-derived mesenchymal stem cells against oxygen/glucose and serum deprivation-induced apoptosis through the activation of the cAMP/PKA signaling pathway and the attenuation of ER stress.
He J; Wang C; Sun Y; Lu B; Cui J; Dong N; Zhang M; Liu Y; Yu B
Int J Mol Med; 2016 Apr; 37(4):889-900. PubMed ID: 26935620
[TBL] [Abstract][Full Text] [Related]
32. Subthreshold α₂-adrenergic activation counteracts glucagon-like peptide-1 potentiation of glucose-stimulated insulin secretion.
Pan M; Yang G; Cui X; Yang SN
Exp Diabetes Res; 2011; 2011():604989. PubMed ID: 21253359
[TBL] [Abstract][Full Text] [Related]
33. Combined contributions of over-secreted glucagon-like peptide 1 and suppressed insulin secretion to hyperglycemia induced by gatifloxacin in rats.
Yu Y; Wang X; Liu C; Yao D; Hu M; Li J; Hu N; Liu L; Liu X
Toxicol Appl Pharmacol; 2013 Feb; 266(3):375-84. PubMed ID: 23200776
[TBL] [Abstract][Full Text] [Related]
34. Glucagon-like peptide 1 receptor plays an essential role in geniposide attenuating lipotoxicity-induced β-cell apoptosis.
Liu J; Yin F; Xiao H; Guo L; Gao X
Toxicol In Vitro; 2012 Oct; 26(7):1093-7. PubMed ID: 22819839
[TBL] [Abstract][Full Text] [Related]
35. GLP-1 receptor localization in monkey and human tissue: novel distribution revealed with extensively validated monoclonal antibody.
Pyke C; Heller RS; Kirk RK; Ørskov C; Reedtz-Runge S; Kaastrup P; Hvelplund A; Bardram L; Calatayud D; Knudsen LB
Endocrinology; 2014 Apr; 155(4):1280-90. PubMed ID: 24467746
[TBL] [Abstract][Full Text] [Related]
36. ER stress and unfolded protein response (UPR) signaling modulate GLP-1 receptor signaling in the pancreatic islets.
Gao Y; Ryu H; Lee H; Kim YJ; Lee JH; Lee J
Mol Cells; 2024 Jan; 47(1):100004. PubMed ID: 38376482
[TBL] [Abstract][Full Text] [Related]
37. Metabolic stability, receptor binding, cAMP generation, insulin secretion and antihyperglycaemic activity of novel N-terminal Glu9-substituted analogues of glucagon-like peptide-1.
Green BD; Gault VA; Irwin N; Mooney MH; Bailey CJ; Harriott P; Greer B; Flatt PR; O'Harte FP
Biol Chem; 2003 Dec; 384(12):1543-51. PubMed ID: 14719796
[TBL] [Abstract][Full Text] [Related]
38. Transfection of pancreatic-derived beta-cells with a minigene encoding for human glucagon-like peptide-1 regulates glucose-dependent insulin synthesis and secretion.
Hui H; Yu R; Bousquet C; Perfetti R
Endocrinology; 2002 Sep; 143(9):3529-39. PubMed ID: 12193567
[TBL] [Abstract][Full Text] [Related]
39. Absence of glucagon and insulin action reveals a role for the GLP-1 receptor in endogenous glucose production.
Jun LS; Millican RL; Hawkins ED; Konkol DL; Showalter AD; Christe ME; Michael MD; Sloop KW
Diabetes; 2015 Mar; 64(3):819-27. PubMed ID: 25288673
[TBL] [Abstract][Full Text] [Related]
40. Glucagon receptor antagonist-mediated improvements in glycemic control are dependent on functional pancreatic GLP-1 receptor.
Gu W; Winters KA; Motani AS; Komorowski R; Zhang Y; Liu Q; Wu X; Rulifson IC; Sivits G; Graham M; Yan H; Wang P; Moore S; Meng T; Lindberg RA; Véniant MM
Am J Physiol Endocrinol Metab; 2010 Oct; 299(4):E624-32. PubMed ID: 20647556
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]