BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 21946521)

  • 1. Taccalonolides: a microtubule stabilizer poses a new puzzle with old pieces.
    Sackett DL; Fojo T
    Cell Cycle; 2011 Oct; 10(19):3233-4. PubMed ID: 21946521
    [No Abstract]   [Full Text] [Related]  

  • 2. The taccalonolides and paclitaxel cause distinct effects on microtubule dynamics and aster formation.
    Risinger AL; Riffle SM; Lopus M; Jordan MA; Wilson L; Mooberry SL
    Mol Cancer; 2014 Feb; 13():41. PubMed ID: 24576146
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Taccalonolides: Novel microtubule stabilizers with clinical potential.
    Risinger AL; Mooberry SL
    Cancer Lett; 2010 May; 291(1):14-9. PubMed ID: 19880245
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Taccalonolide microtubule stabilizers.
    Li J; Risinger AL; Mooberry SL
    Bioorg Med Chem; 2014 Sep; 22(18):5091-6. PubMed ID: 24491636
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Taccalonolide binding to tubulin imparts microtubule stability and potent in vivo activity.
    Risinger AL; Li J; Bennett MJ; Rohena CC; Peng J; Schriemer DC; Mooberry SL
    Cancer Res; 2013 Nov; 73(22):6780-92. PubMed ID: 24048820
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cellular studies reveal mechanistic differences between taccalonolide A and paclitaxel.
    Risinger AL; Mooberry SL
    Cell Cycle; 2011 Jul; 10(13):2162-71. PubMed ID: 21597323
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of C-6 as a New Site for Linker Conjugation to the Taccalonolide Microtubule Stabilizers.
    Du L; Risinger AL; Yee SS; Ola ARB; Zammiello CL; Cichewicz RH; Mooberry SL
    J Nat Prod; 2019 Mar; 82(3):583-588. PubMed ID: 30799622
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chemically diverse microtubule stabilizing agents initiate distinct mitotic defects and dysregulated expression of key mitotic kinases.
    Rohena CC; Peng J; Johnson TA; Crews P; Mooberry SL
    Biochem Pharmacol; 2013 Apr; 85(8):1104-14. PubMed ID: 23399639
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular dynamics simulation and free energy landscape methods in probing L215H, L217R and L225M βI-tubulin mutations causing paclitaxel resistance in cancer cells.
    Tripathi S; Srivastava G; Sharma A
    Biochem Biophys Res Commun; 2016 Aug; 476(4):273-279. PubMed ID: 27233604
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potent taccalonolides, AF and AJ, inform significant structure-activity relationships and tubulin as the binding site of these microtubule stabilizers.
    Li J; Risinger AL; Peng J; Chen Z; Hu L; Mooberry SL
    J Am Chem Soc; 2011 Nov; 133(47):19064-7. PubMed ID: 22040100
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms.
    Risinger AL; Jackson EM; Polin LA; Helms GL; LeBoeuf DA; Joe PA; Hopper-Borge E; Ludueña RF; Kruh GD; Mooberry SL
    Cancer Res; 2008 Nov; 68(21):8881-8. PubMed ID: 18974132
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Taccalonolide C-6 Analogues, Including Paclitaxel Hybrids, Demonstrate Improved Microtubule Polymerizing Activities.
    Risinger AL; Hastings SD; Du L
    J Nat Prod; 2021 Jun; 84(6):1799-1805. PubMed ID: 34110822
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Taccalonolides E and A: Plant-derived steroids with microtubule-stabilizing activity.
    Tinley TL; Randall-Hlubek DA; Leal RM; Jackson EM; Cessac JW; Quada JC; Hemscheidt TK; Mooberry SL
    Cancer Res; 2003 Jun; 63(12):3211-20. PubMed ID: 12810650
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanical effects of EB1 on microtubules depend on GTP hydrolysis state and presence of paclitaxel.
    Lopez BJ; Valentine MT
    Cytoskeleton (Hoboken); 2014 Sep; 71(9):530-41. PubMed ID: 25160006
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CENP-E checks in microtubule-drug resistance.
    Chanel-Vos C; Giannakakou P
    Cell Cycle; 2010 Apr; 9(8):1456. PubMed ID: 20421712
    [No Abstract]   [Full Text] [Related]  

  • 16. Class III β-tubulin counteracts the ability of paclitaxel to inhibit cell migration.
    Ganguly A; Yang H; Cabral F
    Oncotarget; 2011 May; 2(5):368-77. PubMed ID: 21576762
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Taccalonolide Microtubule Stabilizers.
    Yee SS; Du L; Risinger AL
    Prog Chem Org Nat Prod; 2020; 112():183-206. PubMed ID: 33306174
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Heightened sensitivity to paclitaxel in Class IVa beta-tubulin-transfected cells is lost as expression increases.
    Yang H; Cabral F
    J Biol Chem; 2007 Sep; 282(37):27058-27066. PubMed ID: 17627938
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overexpression of mitotic centromere-associated Kinesin stimulates microtubule detachment and confers resistance to paclitaxel.
    Ganguly A; Yang H; Cabral F
    Mol Cancer Ther; 2011 Jun; 10(6):929-37. PubMed ID: 21471284
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Microtubule stabilization by peloruside A and paclitaxel rescues degenerating neurons from okadaic acid-induced tau phosphorylation.
    Das V; Miller JH
    Eur J Neurosci; 2012 Jun; 35(11):1705-17. PubMed ID: 22594877
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.