289 related articles for article (PubMed ID: 2194674)
1. Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
Reiss Y; Goldstein JL; Seabra MC; Casey PJ; Brown MS
Cell; 1990 Jul; 62(1):81-8. PubMed ID: 2194674
[TBL] [Abstract][Full Text] [Related]
2. Tetrapeptide inhibitors of protein farnesyltransferase: amino-terminal substitution in phenylalanine-containing tetrapeptides restores farnesylation.
Brown MS; Goldstein JL; Paris KJ; Burnier JP; Marsters JC
Proc Natl Acad Sci U S A; 1992 Sep; 89(17):8313-6. PubMed ID: 1518863
[TBL] [Abstract][Full Text] [Related]
3. Polyisoprenylation of Ras in vitro by a farnesyl-protein transferase.
Schaber MD; O'Hara MB; Garsky VM; Mosser SC; Bergstrom JD; Moores SL; Marshall MS; Friedman PA; Dixon RA; Gibbs JB
J Biol Chem; 1990 Sep; 265(25):14701-4. PubMed ID: 2203759
[TBL] [Abstract][Full Text] [Related]
4. Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase.
Reiss Y; Stradley SJ; Gierasch LM; Brown MS; Goldstein JL
Proc Natl Acad Sci U S A; 1991 Feb; 88(3):732-6. PubMed ID: 1992464
[TBL] [Abstract][Full Text] [Related]
5. Nonidentical subunits of p21H-ras farnesyltransferase. Peptide binding and farnesyl pyrophosphate carrier functions.
Reiss Y; Seabra MC; Armstrong SA; Slaughter CA; Goldstein JL; Brown MS
J Biol Chem; 1991 Jun; 266(16):10672-7. PubMed ID: 2037606
[TBL] [Abstract][Full Text] [Related]
6. Purification of a mammalian protein geranylgeranyltransferase. Formation and catalytic properties of an enzyme-geranylgeranyl pyrophosphate complex.
Yokoyama K; Gelb MH
J Biol Chem; 1993 Feb; 268(6):4055-60. PubMed ID: 8440698
[TBL] [Abstract][Full Text] [Related]
7. Potent inhibition of human tumor p21ras farnesyltransferase by A1A2-lacking p21ras CA1A2X peptidomimetics.
Nigam M; Seong CM; Qian Y; Hamilton AD; Sebti SM
J Biol Chem; 1993 Oct; 268(28):20695-8. PubMed ID: 8407887
[TBL] [Abstract][Full Text] [Related]
8. Novel tricyclic inhibitors of farnesyl protein transferase. Biochemical characterization and inhibition of Ras modification in transfected Cos cells.
Bishop WR; Bond R; Petrin J; Wang L; Patton R; Doll R; Njoroge G; Catino J; Schwartz J; Windsor W
J Biol Chem; 1995 Dec; 270(51):30611-8. PubMed ID: 8530497
[TBL] [Abstract][Full Text] [Related]
9. Mutational analysis of alpha-subunit of protein farnesyltransferase. Evidence for a catalytic role.
Andres DA; Goldstein JL; Ho YK; Brown MS
J Biol Chem; 1993 Jan; 268(2):1383-90. PubMed ID: 8419339
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of farnesyl transferases from malignant and non-malignant cultured human lymphocytes by prenyl substrate analogues.
Das NP; Allen CM
Biochem Biophys Res Commun; 1991 Dec; 181(2):729-35. PubMed ID: 1755854
[TBL] [Abstract][Full Text] [Related]
11. Different analogues of farnesyl pyrophosphate inhibit squalene synthase and protein:farnesyltransferase to different extents.
Cohen LH; Valentijn AR; Roodenburg L; Van Leeuwen RE; Huisman RH; Lutz RJ; Van der Marel GA; Van Boom JH
Biochem Pharmacol; 1995 Mar; 49(6):839-45. PubMed ID: 7702642
[TBL] [Abstract][Full Text] [Related]
12. Nonfarnesylated tetrapeptide inhibitors of protein farnesyltransferase.
Goldstein JL; Brown MS; Stradley SJ; Reiss Y; Gierasch LM
J Biol Chem; 1991 Aug; 266(24):15575-8. PubMed ID: 1874715
[TBL] [Abstract][Full Text] [Related]
13. Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys.
Seabra MC; Goldstein JL; Südhof TC; Brown MS
J Biol Chem; 1992 Jul; 267(20):14497-503. PubMed ID: 1321151
[TBL] [Abstract][Full Text] [Related]
14. Functional consequence of mutating conserved residues of the yeast farnesyl-protein transferase beta-subunit Ram1(Dpr1).
Kurth DD; Farh L; Deschenes RJ
Biochemistry; 1997 Dec; 36(50):15932-9. PubMed ID: 9398327
[TBL] [Abstract][Full Text] [Related]
15. Protein farnesyltransferase: measurement of enzymatic activity in 96-well format using TopCount microplate scintillation counting technology.
Harwood HJ
Anal Biochem; 1995 Apr; 226(2):268-78. PubMed ID: 7793628
[TBL] [Abstract][Full Text] [Related]
16. Design and structural requirements of potent peptidomimetic inhibitors of p21ras farnesyltransferase.
Qian Y; Blaskovich MA; Saleem M; Seong CM; Wathen SP; Hamilton AD; Sebti SM
J Biol Chem; 1994 Apr; 269(17):12410-3. PubMed ID: 8175645
[TBL] [Abstract][Full Text] [Related]
17. Geranylgeranyl diphosphate synthase catalyzing the single condensation between isopentenyl diphosphate and farnesyl diphosphate.
Sagami H; Korenaga T; Ogura K
J Biochem; 1993 Jul; 114(1):118-21. PubMed ID: 8407863
[TBL] [Abstract][Full Text] [Related]
18. Posttranslational modification of Ha-ras p21 by farnesyl versus geranylgeranyl isoprenoids is determined by the COOH-terminal amino acid.
Kinsella BT; Erdman RA; Maltese WA
Proc Natl Acad Sci U S A; 1991 Oct; 88(20):8934-8. PubMed ID: 1924354
[TBL] [Abstract][Full Text] [Related]
19. Characterization of Xenopus laevis oocyte farnesyl transferase.
Goalstone ML; Diamond CL; Sadler SE
Biol Reprod; 1996 Mar; 54(3):675-81. PubMed ID: 8835391
[TBL] [Abstract][Full Text] [Related]
20. Farnesyl protein transferase inhibitors as potential cancer chemopreventives.
Kelloff GJ; Lubet RA; Fay JR; Steele VE; Boone CW; Crowell JA; Sigman CC
Cancer Epidemiol Biomarkers Prev; 1997 Apr; 6(4):267-82. PubMed ID: 9107432
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
