These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

101 related articles for article (PubMed ID: 21948463)

  • 1. Identification of novel and selective Kv2 channel inhibitors.
    Herrington J; Solly K; Ratliff KS; Li N; Zhou YP; Howard A; Kiss L; Garcia ML; McManus OB; Deng Q; Desai R; Xiong Y; Kaczorowski GJ
    Mol Pharmacol; 2011 Dec; 80(6):959-64. PubMed ID: 21948463
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substitution of a single residue in Stichodactyla helianthus peptide, ShK-Dap22, reveals a novel pharmacological profile.
    Middleton RE; Sanchez M; Linde AR; Bugianesi RM; Dai G; Felix JP; Koprak SL; Staruch MJ; Bruguera M; Cox R; Ghosh A; Hwang J; Jones S; Kohler M; Slaughter RS; McManus OB; Kaczorowski GJ; Garcia ML
    Biochemistry; 2003 Nov; 42(46):13698-707. PubMed ID: 14622016
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties.
    Peigneur S; Billen B; Derua R; Waelkens E; Debaveye S; Béress L; Tytgat J
    Biochem Pharmacol; 2011 Jul; 82(1):81-90. PubMed ID: 21477583
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovering potassium channel blockers from synthetic compound database by using structure-based virtual screening in conjunction with electrophysiological assay.
    Liu H; Gao ZB; Yao Z; Zheng S; Li Y; Zhu W; Tan X; Luo X; Shen J; Chen K; Hu GY; Jiang H
    J Med Chem; 2007 Jan; 50(1):83-93. PubMed ID: 17201412
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An automated electrophysiology serum shift assay for K(V) channels.
    Ratliff KS; Petrov A; Eiermann GJ; Deng Q; Green MD; Kaczorowski GJ; McManus OB; Herrington J
    Assay Drug Dev Technol; 2008 Apr; 6(2):243-53. PubMed ID: 18471078
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of novel Kv1.3 blockers using a fluorescent cell-based ion channel assay.
    Slack M; Kirchhoff C; Moller C; Winkler D; Netzer R
    J Biomol Screen; 2006 Feb; 11(1):57-64. PubMed ID: 16314404
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High-throughput screening for Kv1.3 channel blockers using an improved FLIPR-based membrane-potential assay.
    Liu K; Samuel M; Tillett J; Hennan JK; Mekonnen B; Soloveva V; Harrison RK; Paslay JW; Larocque J
    J Biomol Screen; 2010 Feb; 15(2):185-95. PubMed ID: 20044579
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective, direct activation of high-conductance, calcium-activated potassium channels causes smooth muscle relaxation.
    Ponte CG; McManus OB; Schmalhofer WA; Shen DM; Dai G; Stevenson A; Sur S; Shah T; Kiss L; Shu M; Doherty JB; Nargund R; Kaczorowski GJ; Suarez-Kurtz G; Garcia ML
    Mol Pharmacol; 2012 Apr; 81(4):567-77. PubMed ID: 22241372
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel, potent inhibitors of human Kv1.5 K+ channels and ultrarapidly activating delayed rectifier potassium current.
    Lagrutta A; Wang J; Fermini B; Salata JJ
    J Pharmacol Exp Ther; 2006 Jun; 317(3):1054-63. PubMed ID: 16522807
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oxyhemoglobin-induced suppression of voltage-dependent K+ channels in cerebral arteries by enhanced tyrosine kinase activity.
    Ishiguro M; Morielli AD; Zvarova K; Tranmer BI; Penar PL; Wellman GC
    Circ Res; 2006 Nov; 99(11):1252-60. PubMed ID: 17068294
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Janus-faced atracotoxins are specific blockers of invertebrate K(Ca) channels.
    Gunning SJ; Maggio F; Windley MJ; Valenzuela SM; King GF; Nicholson GM
    FEBS J; 2008 Aug; 275(16):4045-59. PubMed ID: 18625007
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Voltage gated K+ channel expression in arteries of Wistar-Kyoto and spontaneously hypertensive rats.
    Cox RH; Fromme SJ; Folander KL; Swanson RJ
    Am J Hypertens; 2008 Feb; 21(2):213-8. PubMed ID: 18174882
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparison of the endogenous IK currents in rat hippocampal neurons and cloned Kv2.1 channels in CHO cells.
    Liu M; Gong B; Qi Z
    Cell Biol Int; 2008 Dec; 32(12):1514-20. PubMed ID: 18801450
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Di-substituted cyclohexyl derivatives bind to two identical sites with positive cooperativity on the voltage-gated potassium channel, K(v)1.3.
    Schmalhofer WA; Slaughter RS; Matyskiela M; Felix JP; Tang YS; Rupprecht K; Kaczorowski GJ; Garcia ML
    Biochemistry; 2003 Apr; 42(16):4733-43. PubMed ID: 12705837
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The new kappa-KTx 2.5 from the scorpion Opisthacanthus cayaporum.
    Camargos TS; Restano-Cassulini R; Possani LD; Peigneur S; Tytgat J; Schwartz CA; Alves EM; de Freitas SM; Schwartz EF
    Peptides; 2011 Jul; 32(7):1509-17. PubMed ID: 21624408
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Voltage-gated k+ channel block by catechol derivatives: defining nonselective and selective pharmacophores.
    Salvador-Recatala V; Kim Y; Zaks-Makhina E; Levitan ES
    J Pharmacol Exp Ther; 2006 Nov; 319(2):758-64. PubMed ID: 16880198
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification and biochemical characterization of a novel nortriterpene inhibitor of the human lymphocyte voltage-gated potassium channel, Kv1.3.
    Felix JP; Bugianesi RM; Schmalhofer WA; Borris R; Goetz MA; Hensens OD; Bao JM; Kayser F; Parsons WH; Rupprecht K; Garcia ML; Kaczorowski GJ; Slaughter RS
    Biochemistry; 1999 Apr; 38(16):4922-30. PubMed ID: 10213593
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design of PAP-1, a selective small molecule Kv1.3 blocker, for the suppression of effector memory T cells in autoimmune diseases.
    Schmitz A; Sankaranarayanan A; Azam P; Schmidt-Lassen K; Homerick D; Hänsel W; Wulff H
    Mol Pharmacol; 2005 Nov; 68(5):1254-70. PubMed ID: 16099841
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition by bis(7)-tacrine of native delayed rectifier and KV1.2 encoded potassium channels.
    Nie H; Yu WJ; Li XY; Yuan CH; Pang YP; Li CY; Han YF; Li ZW
    Neurosci Lett; 2007 Jan; 412(2):108-13. PubMed ID: 17174470
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Margatoxin binds to a homomultimer of K(V)1.3 channels in Jurkat cells. Comparison with K(V)1.3 expressed in CHO cells.
    Helms LM; Felix JP; Bugianesi RM; Garcia ML; Stevens S; Leonard RJ; Knaus HG; Koch R; Wanner SG; Kaczorowski GJ; Slaughter RS
    Biochemistry; 1997 Mar; 36(12):3737-44. PubMed ID: 9132027
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.