BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

306 related articles for article (PubMed ID: 21949501)

  • 1. Interactions of AChE with Aβ Aggregates in Alzheimer's Brain: Therapeutic Relevance of IDN 5706.
    Carvajal FJ; Inestrosa NC
    Front Mol Neurosci; 2011; 4():19. PubMed ID: 21949501
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 6-Methyluracil derivatives as acetylcholinesterase inhibitors for treatment of Alzheimer's disease.
    Zueva IV; Semenov VE; Mukhamedyarov MA; Lushchekina SV; Kharlamova AD; Petukhova EO; Mikhailov AS; Podyachev SN; Saifina LF; Petrov KA; Minnekhanova OA; Zobov VV; Nikolsky EE; Masson P; Reznik VS
    Int J Risk Saf Med; 2015; 27 Suppl 1():S69-71. PubMed ID: 26639718
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tetrahydrohyperforin decreases cholinergic markers associated with amyloid-β plaques, 4-hydroxynonenal formation, and caspase-3 activation in AβPP/PS1 mice.
    Carvajal FJ; Zolezzi JM; Tapia-Rojas C; Godoy JA; Inestrosa NC
    J Alzheimers Dis; 2013; 36(1):99-118. PubMed ID: 23568104
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice.
    Dinamarca MC; Arrázola M; Toledo E; Cerpa WF; Hancke J; Inestrosa NC
    Chem Biol Interact; 2008 Sep; 175(1-3):142-9. PubMed ID: 18599028
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Acetylcholinesterase-amyloid-beta-peptide interaction: effect of Congo Red and the role of the Wnt pathway.
    Inestrosa NC; Alvarez A; Dinamarca MC; Pérez-Acle T; Colombres M
    Curr Alzheimer Res; 2005 Jul; 2(3):301-6. PubMed ID: 15974895
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Silibinin inhibits acetylcholinesterase activity and amyloid β peptide aggregation: a dual-target drug for the treatment of Alzheimer's disease.
    Duan S; Guan X; Lin R; Liu X; Yan Y; Lin R; Zhang T; Chen X; Huang J; Sun X; Li Q; Fang S; Xu J; Yao Z; Gu H
    Neurobiol Aging; 2015 May; 36(5):1792-807. PubMed ID: 25771396
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neurotoxicity of acetylcholinesterase amyloid beta-peptide aggregates is dependent on the type of Abeta peptide and the AChE concentration present in the complexes.
    Muñoz FJ; Inestrosa NC
    FEBS Lett; 1999 May; 450(3):205-9. PubMed ID: 10359075
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sex differences in hippocampal β-amyloid accumulation in the triple-transgenic mouse model of Alzheimer's disease and the potential role of local estrogens.
    Hu YT; Chen XL; Zhang YN; McGurran H; Stormmesand J; Breeuwsma N; Sluiter A; Zhao J; Swaab D; Bao AM
    Front Neurosci; 2023; 17():1117584. PubMed ID: 36968493
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stable complexes involving acetylcholinesterase and amyloid-beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils.
    Alvarez A; Alarcón R; Opazo C; Campos EO; Muñoz FJ; Calderón FH; Dajas F; Gentry MK; Doctor BP; De Mello FG; Inestrosa NC
    J Neurosci; 1998 May; 18(9):3213-23. PubMed ID: 9547230
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bis(9)-(-)-Meptazinol, a novel dual-binding AChE inhibitor, rescues cognitive deficits and pathological changes in APP/PS1 transgenic mice.
    Shi Y; Huang W; Wang Y; Zhang R; Hou L; Xu J; Qiu Z; Xie Q; Chen H; Zhang Y; Wang H
    Transl Neurodegener; 2018; 7():21. PubMed ID: 30237878
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils.
    Alvarez A; Opazo C; Alarcón R; Garrido J; Inestrosa NC
    J Mol Biol; 1997 Sep; 272(3):348-61. PubMed ID: 9325095
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Acetylcholinesterase interaction with Alzheimer amyloid beta.
    Inestrosa NC; Sagal JP; Colombres M
    Subcell Biochem; 2005; 38():299-317. PubMed ID: 15709485
    [TBL] [Abstract][Full Text] [Related]  

  • 13.
    Jean L; Brimijoin S; Vaux DJ
    J Biol Chem; 2019 Apr; 294(16):6253-6272. PubMed ID: 30787102
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models.
    Sebastian Monasor L; Müller SA; Colombo AV; Tanrioever G; König J; Roth S; Liesz A; Berghofer A; Piechotta A; Prestel M; Saito T; Saido TC; Herms J; Willem M; Haass C; Lichtenthaler SF; Tahirovic S
    Elife; 2020 Jun; 9():. PubMed ID: 32510331
    [TBL] [Abstract][Full Text] [Related]  

  • 15. β-Amyloid, cholinergic transmission, and cerebrovascular system -- a developmental study in a mouse model of Alzheimer's disease.
    Kuznetsova E; Schliebs R
    Curr Pharm Des; 2013; 19(38):6749-65. PubMed ID: 23530514
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
    Jaffar S; Counts SE; Ma SY; Dadko E; Gordon MN; Morgan D; Mufson EJ
    Exp Neurol; 2001 Aug; 170(2):227-43. PubMed ID: 11476589
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acetylcholinesterase protein level is preserved in the Alzheimer's brain.
    Campanari ML; García-Ayllón MS; Blazquez-Llorca L; Luk WK; Tsim K; Sáez-Valero J
    J Mol Neurosci; 2014 Jul; 53(3):446-53. PubMed ID: 24318838
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Association between acetylcholinesterase and beta-amyloid peptide in Alzheimer's cerebrospinal fluid.
    García-Ayllón MS; Silveyra MX; Sáez-Valero J
    Chem Biol Interact; 2008 Sep; 175(1-3):209-15. PubMed ID: 18554581
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-function implications in Alzheimer's disease: effect of Abeta oligomers at central synapses.
    Cerpa W; Dinamarca MC; Inestrosa NC
    Curr Alzheimer Res; 2008 Jun; 5(3):233-43. PubMed ID: 18537540
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Novel Multifunctional 5,6-Dimethoxy-Indanone-Chalcone-Carbamate Hybrids Alleviates Cognitive Decline in Alzheimer's Disease by Dual Inhibition of Acetylcholinesterase and Inflammation.
    Liu C; Sang Z; Pan H; Wu Q; Qiu Y; Shi J
    Front Aging Neurosci; 2022; 14():922650. PubMed ID: 35860673
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.