337 related articles for article (PubMed ID: 21949677)
21. RACK1 vs. HSP90: competition for HIF-1 alpha degradation vs. stabilization.
Liu YV; Semenza GL
Cell Cycle; 2007 Mar; 6(6):656-9. PubMed ID: 17361105
[TBL] [Abstract][Full Text] [Related]
22. RACK1 competes with HSP90 for binding to HIF-1alpha and is required for O(2)-independent and HSP90 inhibitor-induced degradation of HIF-1alpha.
Liu YV; Baek JH; Zhang H; Diez R; Cole RN; Semenza GL
Mol Cell; 2007 Jan; 25(2):207-17. PubMed ID: 17244529
[TBL] [Abstract][Full Text] [Related]
23. Histone deacetylase inhibitor induced pVHL-independent degradation of HIF-1α and hierarchical quality control of pVHL via chaperone system.
Ni J; Ni A
PLoS One; 2021; 16(7):e0248019. PubMed ID: 34329303
[TBL] [Abstract][Full Text] [Related]
24. Hypoxia-regulated expression of attenuated diphtheria toxin A fused with hypoxia-inducible factor-1alpha oxygen-dependent degradation domain preferentially induces apoptosis of hypoxic cells in solid tumor.
Koshikawa N; Takenaga K
Cancer Res; 2005 Dec; 65(24):11622-30. PubMed ID: 16357173
[TBL] [Abstract][Full Text] [Related]
25. DNA-dependent protein kinase is involved in heat shock protein-mediated accumulation of hypoxia-inducible factor-1alpha in hypoxic preconditioned HepG2 cells.
Kang MJ; Jung SM; Kim MJ; Bae JH; Kim HB; Kim JY; Park SJ; Song HS; Kim DW; Kang CD; Kim SH
FEBS J; 2008 Dec; 275(23):5969-81. PubMed ID: 19021771
[TBL] [Abstract][Full Text] [Related]
26. Inhibitory action of Celastrol on hypoxia-mediated angiogenesis and metastasis via the HIF-1α pathway.
Huang L; Zhang Z; Zhang S; Ren J; Zhang R; Zeng H; Li Q; Wu G
Int J Mol Med; 2011 Mar; 27(3):407-15. PubMed ID: 21249310
[TBL] [Abstract][Full Text] [Related]
27. Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization.
Liu YV; Hubbi ME; Pan F; McDonald KR; Mansharamani M; Cole RN; Liu JO; Semenza GL
J Biol Chem; 2007 Dec; 282(51):37064-73. PubMed ID: 17965024
[TBL] [Abstract][Full Text] [Related]
28. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
[TBL] [Abstract][Full Text] [Related]
29. Rhapontigenin inhibited hypoxia inducible factor 1 alpha accumulation and angiogenesis in hypoxic PC-3 prostate cancer cells.
Jung DB; Lee HJ; Jeong SJ; Lee HJ; Lee EO; Kim YC; Ahn KS; Chen CY; Kim SH
Biol Pharm Bull; 2011; 34(6):850-5. PubMed ID: 21628883
[TBL] [Abstract][Full Text] [Related]
30. The potential role of hypoxia inducible factor 1alpha in tumor progression after hypoxia and chemotherapy in hepatocellular carcinoma.
Yang ZF; Poon RT; To J; Ho DW; Fan ST
Cancer Res; 2004 Aug; 64(15):5496-503. PubMed ID: 15289360
[TBL] [Abstract][Full Text] [Related]
31. Effects of YC-1 on hypoxia-inducible factor 1 alpha in hypoxic human bladder transitional carcinoma cell line T24 cells.
Li Y; Zhao X; Tang H; Zhong Z; Zhang L; Xu R; Li S; Wang Y
Urol Int; 2012; 88(1):95-101. PubMed ID: 22041818
[TBL] [Abstract][Full Text] [Related]
32. Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition.
Chintala S; Najrana T; Toth K; Cao S; Durrani FA; Pili R; Rustum YM
BMC Cancer; 2012 Jul; 12():293. PubMed ID: 22804960
[TBL] [Abstract][Full Text] [Related]
33. Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha.
Shinojima T; Oya M; Takayanagi A; Mizuno R; Shimizu N; Murai M
Carcinogenesis; 2007 Mar; 28(3):529-36. PubMed ID: 16920734
[TBL] [Abstract][Full Text] [Related]
34. Fasudil-induced hypoxia-inducible factor-1alpha degradation disrupts a hypoxia-driven vascular endothelial growth factor autocrine mechanism in endothelial cells.
Takata K; Morishige K; Takahashi T; Hashimoto K; Tsutsumi S; Yin L; Ohta T; Kawagoe J; Takahashi K; Kurachi H
Mol Cancer Ther; 2008 Jun; 7(6):1551-61. PubMed ID: 18566226
[TBL] [Abstract][Full Text] [Related]
35. Antisense-thioredoxin inhibits angiogenesis via pVHL-mediated hypoxia-inducible factor-1alpha degradation.
Kim WJ; Cho H; Lee SW; Kim YJ; Kim KW
Int J Oncol; 2005 Apr; 26(4):1049-52. PubMed ID: 15754001
[TBL] [Abstract][Full Text] [Related]
36. Identification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alpha.
André H; Pereira TS
J Biol Chem; 2008 Oct; 283(43):29375-84. PubMed ID: 18694926
[TBL] [Abstract][Full Text] [Related]
37. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
Blancher C; Moore JW; Robertson N; Harris AL
Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
[TBL] [Abstract][Full Text] [Related]
38. A group of novel HIF-1α inhibitors, glyceollins, blocks HIF-1α synthesis and decreases its stability via inhibition of the PI3K/AKT/mTOR pathway and Hsp90 binding.
Lee SH; Jee JG; Bae JS; Liu KH; Lee YM
J Cell Physiol; 2015 Apr; 230(4):853-62. PubMed ID: 25204544
[TBL] [Abstract][Full Text] [Related]
39. Antiangiogenic effects of ganetespib in colorectal cancer mediated through inhibition of HIF-1α and STAT-3.
Nagaraju GP; Park W; Wen J; Mahaseth H; Landry J; Farris AB; Willingham F; Sullivan PS; Proia DA; El-Hariry I; Taliaferro-Smith L; Diaz R; El-Rayes BF
Angiogenesis; 2013 Oct; 16(4):903-17. PubMed ID: 23838996
[TBL] [Abstract][Full Text] [Related]
40. STAT3 inhibits the degradation of HIF-1alpha by pVHL-mediated ubiquitination.
Jung JE; Kim HS; Lee CS; Shin YJ; Kim YN; Kang GH; Kim TY; Juhnn YS; Kim SJ; Park JW; Ye SK; Chung MH
Exp Mol Med; 2008 Oct; 40(5):479-85. PubMed ID: 18985005
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
