BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

229 related articles for article (PubMed ID: 21950761)

  • 1. Quantitative proteomic identification of the BRCA1 ubiquitination substrates.
    Song M; Hakala K; Weintraub ST; Shiio Y
    J Proteome Res; 2011 Nov; 10(11):5191-8. PubMed ID: 21950761
    [TBL] [Abstract][Full Text] [Related]  

  • 2. BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis.
    Salas-Lloret D; García-Rodríguez N; Soto-Hidalgo E; González-Vinceiro L; Espejo-Serrano C; Giebel L; Mateos-Martín ML; de Ru AH; van Veelen PA; Huertas P; Vertegaal ACO; González-Prieto R
    Nat Commun; 2024 May; 15(1):4292. PubMed ID: 38769345
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The BRCA1/BARD1 ubiquitin ligase and its substrates.
    Witus SR; Stewart MD; Klevit RE
    Biochem J; 2021 Sep; 478(18):3467-3483. PubMed ID: 34591954
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Negative feedback loop of BRCA1-BARD1 ubiquitin ligase on estrogen receptor alpha stability and activity antagonized by cancer-associated isoform of BARD1.
    Dizin E; Irminger-Finger I
    Int J Biochem Cell Biol; 2010 May; 42(5):693-700. PubMed ID: 20060929
    [TBL] [Abstract][Full Text] [Related]  

  • 5. mRNA Processing Factor CstF-50 and Ubiquitin Escort Factor p97 Are BRCA1/BARD1 Cofactors Involved in Chromatin Remodeling during the DNA Damage Response.
    Fonseca D; Baquero J; Murphy MR; Aruggoda G; Varriano S; Sapienza C; Mashadova O; Rahman S; Kleiman FE
    Mol Cell Biol; 2018 Feb; 38(4):. PubMed ID: 29180510
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes.
    Stewart MD; Zelin E; Dhall A; Walsh T; Upadhyay E; Corn JE; Chatterjee C; King MC; Klevit RE
    Proc Natl Acad Sci U S A; 2018 Feb; 115(6):1316-1321. PubMed ID: 29367421
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tuning BRCA1 and BARD1 activity to investigate RING ubiquitin ligase mechanisms.
    Stewart MD; Duncan ED; Coronado E; DaRosa PA; Pruneda JN; Brzovic PS; Klevit RE
    Protein Sci; 2017 Mar; 26(3):475-483. PubMed ID: 27977889
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Down-regulation of BRCA1-BARD1 ubiquitin ligase by CDK2.
    Hayami R; Sato K; Wu W; Nishikawa T; Hiroi J; Ohtani-Kaneko R; Fukuda M; Ohta T
    Cancer Res; 2005 Jan; 65(1):6-10. PubMed ID: 15665273
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function.
    Wu-Baer F; Ludwig T; Baer R
    Mol Cell Biol; 2010 Jun; 30(11):2787-98. PubMed ID: 20351172
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BRCA1 DNA-binding activity is stimulated by BARD1.
    Simons AM; Horwitz AA; Starita LM; Griffin K; Williams RS; Glover JN; Parvin JD
    Cancer Res; 2006 Feb; 66(4):2012-8. PubMed ID: 16489000
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Substrates of the BRCA1-dependent ubiquitin ligase.
    Starita LM; Parvin JD
    Cancer Biol Ther; 2006 Feb; 5(2):137-41. PubMed ID: 16479151
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection.
    Densham RM; Garvin AJ; Stone HR; Strachan J; Baldock RA; Daza-Martin M; Fletcher A; Blair-Reid S; Beesley J; Johal B; Pearl LH; Neely R; Keep NH; Watts FZ; Morris JR
    Nat Struct Mol Biol; 2016 Jul; 23(7):647-55. PubMed ID: 27239795
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genetic analysis of BRCA1 ubiquitin ligase activity and its relationship to breast cancer susceptibility.
    Morris JR; Pangon L; Boutell C; Katagiri T; Keep NH; Solomon E
    Hum Mol Genet; 2006 Feb; 15(4):599-606. PubMed ID: 16403807
    [TBL] [Abstract][Full Text] [Related]  

  • 14. BRCA1 control of steroid receptor ubiquitination.
    Heine GF; Parvin JD
    Sci STKE; 2007 Jun; 2007(391):pe34. PubMed ID: 17579243
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression.
    Shakya R; Szabolcs M; McCarthy E; Ospina E; Basso K; Nandula S; Murty V; Baer R; Ludwig T
    Proc Natl Acad Sci U S A; 2008 May; 105(19):7040-5. PubMed ID: 18443292
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair.
    Wang M; Li W; Tomimatsu N; Yu CH; Ji JH; Alejo S; Witus SR; Alimbetov D; Fitzgerald O; Wu B; Wang Q; Huang Y; Gan Y; Dong F; Kwon Y; Sareddy GR; Curiel TJ; Habib AA; Hromas R; Dos Santos Passos C; Yao T; Ivanov DN; Brzovic PS; Burma S; Klevit RE; Zhao W
    Mol Cell; 2023 Oct; 83(20):3679-3691.e8. PubMed ID: 37797621
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BRCA1/BARD1 complex interacts with steroidogenic factor 1--A potential mechanism for regulation of aromatase expression by BRCA1.
    Lu Y; Kang T; Hu Y
    J Steroid Biochem Mol Biol; 2011 Jan; 123(1-2):71-8. PubMed ID: 21087664
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RNF168-mediated localization of BARD1 recruits the BRCA1-PALB2 complex to DNA damage.
    Krais JJ; Wang Y; Patel P; Basu J; Bernhardy AJ; Johnson N
    Nat Commun; 2021 Aug; 12(1):5016. PubMed ID: 34408138
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Liver X receptor ligands suppress ubiquitination and degradation of LXRalpha by displacing BARD1/BRCA1.
    Kim KH; Yoon JM; Choi AH; Kim WS; Lee GY; Kim JB
    Mol Endocrinol; 2009 Apr; 23(4):466-74. PubMed ID: 19164445
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligase.
    Eakin CM; Maccoss MJ; Finney GL; Klevit RE
    Proc Natl Acad Sci U S A; 2007 Apr; 104(14):5794-9. PubMed ID: 17392432
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.