BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 21952924)

  • 1. Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients.
    Gillespie J; Savic S; Wong C; Hempshall A; Inman M; Emery P; Grigg R; McDermott MF
    Arthritis Rheum; 2012 Feb; 64(2):418-22. PubMed ID: 21952924
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Imbalance between HAT and HDAC activities in the PBMCs of patients with ankylosing spondylitis or rheumatoid arthritis and influence of HDAC inhibitors on TNF alpha production.
    Toussirot E; Abbas W; Khan KA; Tissot M; Jeudy A; Baud L; Bertolini E; Wendling D; Herbein G
    PLoS One; 2013; 8(8):e70939. PubMed ID: 24039666
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases.
    Cleophas MC; Crişan TO; Lemmers H; Toenhake-Dijkstra H; Fossati G; Jansen TL; Dinarello CA; Netea MG; Joosten LA
    Ann Rheum Dis; 2016 Mar; 75(3):593-600. PubMed ID: 25589513
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay.
    Grabiec AM; Korchynskyi O; Tak PP; Reedquist KA
    Ann Rheum Dis; 2012 Mar; 71(3):424-31. PubMed ID: 21953341
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Therapeutic effect of a novel histone deacetylase 6 inhibitor, CKD-L, on collagen-induced arthritis in vivo and regulatory T cells in rheumatoid arthritis in vitro.
    Oh BR; Suh DH; Bae D; Ha N; Choi YI; Yoo HJ; Park JK; Lee EY; Lee EB; Song YW
    Arthritis Res Ther; 2017 Jul; 19(1):154. PubMed ID: 28673326
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Intracellular vorinostat accumulation and its relationship to histone deacetylase activity in soft tissue sarcoma patients.
    Burhenne J; Liu L; Heilig CE; Meid AD; Leisen M; Schmitt T; Kasper B; Haefeli WE; Mikus G; Egerer G
    Cancer Chemother Pharmacol; 2017 Aug; 80(2):433-439. PubMed ID: 28612091
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue.
    Grabiec AM; Krausz S; de Jager W; Burakowski T; Groot D; Sanders ME; Prakken BJ; Maslinski W; Eldering E; Tak PP; Reedquist KA
    J Immunol; 2010 Mar; 184(5):2718-28. PubMed ID: 20100935
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of IL-34 on the secretion of RANKL/OPG by fibroblast-like synoviocytes and peripheral blood mononuclear cells in rheumatoid arthritis.
    Cui MY; Li X; Lei YM; Xia LP; Lu J; Shen H
    Eur Cytokine Netw; 2019 Jun; 30(2):67-73. PubMed ID: 31486401
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis.
    Shen H; Goodall JC; Hill Gaston JS
    Arthritis Rheum; 2009 Jun; 60(6):1647-56. PubMed ID: 19479869
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dysregulated serum IL-23 and SIRT1 activity in peripheral blood mononuclear cells of patients with rheumatoid arthritis.
    Wendling D; Abbas W; Godfrin-Valnet M; Kumar A; Guillot X; Khan KA; Vidon C; Coquard L; Toussirot E; Prati C; Herbein G
    PLoS One; 2015; 10(3):e0119981. PubMed ID: 25799392
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Berberine Inhibits the Gene Expression and Production of Proinflammatory Cytokines by Mononuclear Cells in Rheumatoid Arthritis and Healthy Individuals.
    Ghorbani N; Sahebari M; Mahmoudi M; Rastin M; Zamani S; Zamani M
    Curr Rheumatol Rev; 2021; 17(1):113-121. PubMed ID: 32895042
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Histone deacetylases 1 and 2 inhibition suppresses cytokine production and osteoclast bone resorption in vitro.
    Algate K; Haynes D; Fitzsimmons T; Romeo O; Wagner F; Holson E; Reid R; Fairlie D; Bartold P; Cantley M
    J Cell Biochem; 2020 Jan; 121(1):244-258. PubMed ID: 31222845
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo.
    Li S; Fossati G; Marchetti C; Modena D; Pozzi P; Reznikov LL; Moras ML; Azam T; Abbate A; Mascagni P; Dinarello CA
    J Biol Chem; 2015 Jan; 290(4):2368-78. PubMed ID: 25451941
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Therapeutic potential of CKD-506, a novel selective histone deacetylase 6 inhibitor, in a murine model of rheumatoid arthritis.
    Park JK; Jang YJ; Oh BR; Shin J; Bae D; Ha N; Choi YI; Youn GS; Park J; Lee EY; Lee EB; Song YW
    Arthritis Res Ther; 2020 Jul; 22(1):176. PubMed ID: 32711562
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma.
    Radstake TR; Roelofs MF; Jenniskens YM; Oppers-Walgreen B; van Riel PL; Barrera P; Joosten LA; van den Berg WB
    Arthritis Rheum; 2004 Dec; 50(12):3856-65. PubMed ID: 15593217
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reduced Activity of HDAC3 and Increased Acetylation of Histones H3 in Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis.
    Li Y; Zhou M; Lv X; Song L; Zhang D; He Y; Wang M; Zhao X; Yuan X; Shi G; Wang D
    J Immunol Res; 2018; 2018():7313515. PubMed ID: 30402512
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interferon-gamma production in response to in vitro stimulation with collagen type II in rheumatoid arthritis is associated with HLA-DRB1(*)0401 and HLA-DQ8.
    Berg L; Rönnelid J; Sanjeevi CB; Lampa J; Klareskog L
    Arthritis Res; 2000; 2(1):75-84. PubMed ID: 11219392
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of TGR5 alleviates inflammation in rheumatoid arthritis peripheral blood mononuclear cells and in mice with collagen II‑induced arthritis.
    Li ZY; Zhou JJ; Luo CL; Zhang LM
    Mol Med Rep; 2019 Nov; 20(5):4540-4550. PubMed ID: 31702035
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tubastatin, a selective histone deacetylase 6 inhibitor shows anti-inflammatory and anti-rheumatic effects.
    Vishwakarma S; Iyer LR; Muley M; Singh PK; Shastry A; Saxena A; Kulathingal J; Vijaykanth G; Raghul J; Rajesh N; Rathinasamy S; Kachhadia V; Kilambi N; Rajgopal S; Balasubramanian G; Narayanan S
    Int Immunopharmacol; 2013 May; 16(1):72-8. PubMed ID: 23541634
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Trichostatin differentially regulates Th1 and Th2 responses and alleviates rheumatoid arthritis in mice.
    Zhou X; Hua X; Ding X; Bian Y; Wang X
    J Clin Immunol; 2011 Jun; 31(3):395-405. PubMed ID: 21305388
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.