BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

369 related articles for article (PubMed ID: 21953448)

  • 1. Hydrogen sulfide and L-cysteine increase phosphatidylinositol 3,4,5-trisphosphate (PIP3) and glucose utilization by inhibiting phosphatase and tensin homolog (PTEN) protein and activating phosphoinositide 3-kinase (PI3K)/serine/threonine protein kinase (AKT)/protein kinase Cζ/λ (PKCζ/λ) in 3T3l1 adipocytes.
    Manna P; Jain SK
    J Biol Chem; 2011 Nov; 286(46):39848-59. PubMed ID: 21953448
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PIP3 but not PIP2 increases GLUT4 surface expression and glucose metabolism mediated by AKT/PKCζ/λ phosphorylation in 3T3L1 adipocytes.
    Manna P; Jain SK
    Mol Cell Biochem; 2013 Sep; 381(1-2):291-9. PubMed ID: 23749168
    [TBL] [Abstract][Full Text] [Related]  

  • 3. L-cysteine and hydrogen sulfide increase PIP3 and AMPK/PPARγ expression and decrease ROS and vascular inflammation markers in high glucose treated human U937 monocytes.
    Manna P; Jain SK
    J Cell Biochem; 2013 Oct; 114(10):2334-45. PubMed ID: 23733596
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes.
    Tang X; Powelka AM; Soriano NA; Czech MP; Guilherme A
    J Biol Chem; 2005 Jun; 280(23):22523-9. PubMed ID: 15824124
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes.
    Ono H; Katagiri H; Funaki M; Anai M; Inukai K; Fukushima Y; Sakoda H; Ogihara T; Onishi Y; Fujishiro M; Kikuchi M; Oka Y; Asano T
    Mol Endocrinol; 2001 Aug; 15(8):1411-22. PubMed ID: 11463863
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Vitamin D up-regulates glucose transporter 4 (GLUT4) translocation and glucose utilization mediated by cystathionine-γ-lyase (CSE) activation and H2S formation in 3T3L1 adipocytes.
    Manna P; Jain SK
    J Biol Chem; 2012 Dec; 287(50):42324-32. PubMed ID: 23074218
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP).
    Ijuin T; Takenawa T
    J Biol Chem; 2012 Mar; 287(10):6991-9. PubMed ID: 22247557
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular mechanisms of the diabetogenic effects of arsenic: inhibition of insulin signaling by arsenite and methylarsonous acid.
    Paul DS; Harmon AW; Devesa V; Thomas DJ; Stýblo M
    Environ Health Perspect; 2007 May; 115(5):734-42. PubMed ID: 17520061
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes.
    Egawa K; Maegawa H; Shi K; Nakamura T; Obata T; Yoshizaki T; Morino K; Shimizu S; Nishio Y; Suzuki E; Kashiwagi A
    J Biol Chem; 2002 Oct; 277(41):38863-9. PubMed ID: 12147684
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
    Rodríguez-Escudero I; Roelants FM; Thorner J; Nombela C; Molina M; Cid VJ
    Biochem J; 2005 Sep; 390(Pt 2):613-23. PubMed ID: 15913452
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of protein kinase B activity by PTEN and SHIP2 in human prostate-derived cell lines.
    Sharrard RM; Maitland NJ
    Cell Signal; 2007 Jan; 19(1):129-38. PubMed ID: 16842970
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Calmodulin antagonists inhibit insulin-stimulated GLUT4 (glucose transporter 4) translocation by preventing the formation of phosphatidylinositol 3,4,5-trisphosphate in 3T3L1 adipocytes.
    Yang C; Watson RT; Elmendorf JS; Sacks DB; Pessin JE
    Mol Endocrinol; 2000 Feb; 14(2):317-26. PubMed ID: 10674403
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Portulaca oleracea L. Extract Enhances Glucose Uptake by Stimulating GLUT4 Translocation to the Plasma Membrane in 3T3-L1 Adipocytes.
    Park JE; Lee JS; Lee HA; Han JS
    J Med Food; 2018 May; 21(5):462-468. PubMed ID: 29341802
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cbl, IRS-1, and IRS-2 mediate effects of rosiglitazone on PI3K, PKC-lambda, and glucose transport in 3T3/L1 adipocytes.
    Standaert ML; Kanoh Y; Sajan MP; Bandyopadhyay G; Farese RV
    Endocrinology; 2002 May; 143(5):1705-16. PubMed ID: 11956152
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Insulin-sensitive phospholipid signaling systems and glucose transport. Update II.
    Farese RV
    Exp Biol Med (Maywood); 2001 Apr; 226(4):283-95. PubMed ID: 11368419
    [TBL] [Abstract][Full Text] [Related]  

  • 16. l-Cysteine supplementation increases insulin sensitivity mediated by upregulation of GSH and adiponectin in high glucose treated 3T3-L1 adipocytes.
    Achari AE; Jain SK
    Arch Biochem Biophys; 2017 Sep; 630():54-65. PubMed ID: 28755973
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.
    Ugi S; Imamura T; Maegawa H; Egawa K; Yoshizaki T; Shi K; Obata T; Ebina Y; Kashiwagi A; Olefsky JM
    Mol Cell Biol; 2004 Oct; 24(19):8778-89. PubMed ID: 15367694
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.
    Tremblay F; Gagnon A; Veilleux A; Sorisky A; Marette A
    Endocrinology; 2005 Mar; 146(3):1328-37. PubMed ID: 15576463
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes.
    Mahadev K; Wu X; Zilbering A; Zhu L; Lawrence JT; Goldstein BJ
    J Biol Chem; 2001 Dec; 276(52):48662-9. PubMed ID: 11598110
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.
    Jiang ZY; Zhou QL; Holik J; Patel S; Leszyk J; Coleman K; Chouinard M; Czech MP
    J Biol Chem; 2005 Jun; 280(22):21622-8. PubMed ID: 15799971
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.