BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 21955999)

  • 1. Cytotoxicity of human recombinant arginase I (Co)-PEG5000 in the presence of supplemental L-citrulline is dependent on decreased argininosuccinate synthetase expression in human cells.
    Agrawal V; Woo JH; Mauldin JP; Jo C; Stone EM; Georgiou G; Frankel AE
    Anticancer Drugs; 2012 Jan; 23(1):51-64. PubMed ID: 21955999
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells.
    Khoury O; Ghazale N; Stone E; El-Sibai M; Frankel AE; Abi-Habib RJ
    J Neurooncol; 2015 Mar; 122(1):75-85. PubMed ID: 25567351
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells.
    Tanios R; Bekdash A; Kassab E; Stone E; Georgiou G; Frankel AE; Abi-Habib RJ
    Leuk Res; 2013 Nov; 37(11):1565-71. PubMed ID: 24018014
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [HuArgI (co)-PEG5000]-induced arginine deprivation leads to autophagy dependent cell death in pancreatic cancer cells.
    Khalil N; Abi-Habib RJ
    Invest New Drugs; 2020 Oct; 38(5):1236-1246. PubMed ID: 31823161
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human Recombinant Arginase I [HuArgI (Co)-PEG5000]-Induced Arginine Depletion Inhibits Colorectal Cancer Cell Migration and Invasion.
    Al-Koussa H; Al-Haddad M; Abi-Habib R; El-Sibai M
    Int J Mol Sci; 2019 Nov; 20(23):. PubMed ID: 31795337
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Recombinant human arginase inhibits proliferation of human hepatocellular carcinoma by inducing cell cycle arrest.
    Lam TL; Wong GK; Chong HC; Cheng PN; Choi SC; Chow TL; Kwok SY; Poon RT; Wheatley DN; Lo WH; Leung YC
    Cancer Lett; 2009 May; 277(1):91-100. PubMed ID: 19138817
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of autophagy following [HuArgI (Co)-PEG5000]-induced arginine deprivation mediates cell death in colon cancer cells.
    Swayden M; Bekdash A; Fakhoury I; El-Atat O; Borjac-Natour J; El-Sibai M; Abi-Habib RJ
    Hum Cell; 2021 Jan; 34(1):152-164. PubMed ID: 32979152
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human Recombinant Arginase I [HuArgI(Co)-PEG5000]-Induced Arginine Depletion Inhibits Pancreatic Cancer Cell Migration and Invasion Through Autophagy.
    El-Mais N; Fakhoury I; Al Haddad M; Nohra S; Abi-Habib R; El-Sibai M
    Pancreas; 2021 Sep; 50(8):1187-1194. PubMed ID: 34714283
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent.
    Nasreddine G; El-Sibai M; Abi-Habib RJ
    Invest New Drugs; 2020 Feb; 38(1):10-19. PubMed ID: 30887252
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recombinant human arginase toxicity in mice is reduced by citrulline supplementation.
    Mauldin JP; Zeinali I; Kleypas K; Woo JH; Blackwood RS; Jo CH; Stone EM; Georgiou G; Frankel AE
    Transl Oncol; 2012 Feb; 5(1):26-31. PubMed ID: 22348173
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Arginine-metabolizing enzymes in the developing rat small intestine.
    De Jonge WJ; Dingemanse MA; de Boer PA; Lamers WH; Moorman AF
    Pediatr Res; 1998 Apr; 43(4 Pt 1):442-51. PubMed ID: 9544996
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pegylated arginine deiminase (ADI-SS PEG20,000 mw) inhibits human melanomas and hepatocellular carcinomas in vitro and in vivo.
    Ensor CM; Holtsberg FW; Bomalaski JS; Clark MA
    Cancer Res; 2002 Oct; 62(19):5443-50. PubMed ID: 12359751
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cancer cell sensitivity to arginine deprivation in vitro is not determined by endogenous levels of arginine metabolic enzymes.
    Bobak YP; Vynnytska BO; Kurlishchuk YV; Sibirny AA; Stasyk OV
    Cell Biol Int; 2010 Nov; 34(11):1085-9. PubMed ID: 20653567
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pegylated recombinant human arginase (rhArg-peg5,000mw) inhibits the in vitro and in vivo proliferation of human hepatocellular carcinoma through arginine depletion.
    Cheng PN; Lam TL; Lam WM; Tsui SM; Cheng AW; Lo WH; Leung YC
    Cancer Res; 2007 Jan; 67(1):309-17. PubMed ID: 17210712
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes.
    Alexandrou C; Al-Aqbi SS; Higgins JA; Boyle W; Karmokar A; Andreadi C; Luo JL; Moore DA; Viskaduraki M; Blades M; Murray GI; Howells LM; Thomas A; Brown K; Cheng PN; Rufini A
    Sci Rep; 2018 Aug; 8(1):12096. PubMed ID: 30108309
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human recombinant arginase I [HuArgI (Co)-PEG5000]-induced arginine depletion inhibits ovarian cancer cell adhesion and migration through autophagy-mediated inhibition of RhoA.
    El-Mais N; Fakhoury I; Abdellatef S; Abi-Habib R; El-Sibai M
    J Ovarian Res; 2021 Jan; 14(1):13. PubMed ID: 33423701
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Renal cell carcinoma does not express argininosuccinate synthetase and is highly sensitive to arginine deprivation via arginine deiminase.
    Yoon CY; Shim YJ; Kim EH; Lee JH; Won NH; Kim JH; Park IS; Yoon DK; Min BH
    Int J Cancer; 2007 Feb; 120(4):897-905. PubMed ID: 17096330
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Citrulline-argininosuccinate-arginine cycle coupled to Ca2+-signaling in rat pancreatic beta-cells.
    Nakata M; Yada T; Nakagawa S; Kobayashi K; Maruyama I
    Biochem Biophys Res Commun; 1997 Jun; 235(3):619-24. PubMed ID: 9207208
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of chronic renal failure on arginase and argininosuccinate synthetase expression.
    Moradi H; Kwok V; Vaziri ND
    Am J Nephrol; 2006; 26(3):310-8. PubMed ID: 16809898
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of endogenous nitric oxide synthesis in congenital urea cycle enzyme defects.
    Nagasaka H; Tsukahara H; Yorifuji T; Miida T; Murayama K; Tsuruoka T; Takatani T; Kanazawa M; Kobayashi K; Okano Y; Takayanagi M
    Metabolism; 2009 Mar; 58(3):278-82. PubMed ID: 19217439
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.