286 related articles for article (PubMed ID: 21956685)
1. D,L-sulforaphane-induced apoptosis in human breast cancer cells is regulated by the adapter protein p66Shc.
Sakao K; Singh SV
J Cell Biochem; 2012 Feb; 113(2):599-610. PubMed ID: 21956685
[TBL] [Abstract][Full Text] [Related]
2. p66Shc is indispensable for phenethyl isothiocyanate-induced apoptosis in human prostate cancer cells.
Xiao D; Singh SV
Cancer Res; 2010 Apr; 70(8):3150-8. PubMed ID: 20354186
[TBL] [Abstract][Full Text] [Related]
3. Propofol protects against angiotensin II-induced mouse hippocampal HT22 cells apoptosis via inhibition of p66Shc mitochondrial translocation.
Zhu M; Chen J; Wen M; Sun Z; Sun X; Wang J; Miao C
Neuromolecular Med; 2014 Dec; 16(4):772-81. PubMed ID: 25151272
[TBL] [Abstract][Full Text] [Related]
4. Oxidative stress stimulates apoptosis and activates NF-kappaB in osteoblastic cells via a PKCbeta/p66shc signaling cascade: counter regulation by estrogens or androgens.
Almeida M; Han L; Ambrogini E; Bartell SM; Manolagas SC
Mol Endocrinol; 2010 Oct; 24(10):2030-7. PubMed ID: 20685851
[TBL] [Abstract][Full Text] [Related]
5. Selective inhibition of protein kinase C β2 attenuates the adaptor P66 Shc-mediated intestinal ischemia-reperfusion injury.
Chen Z; Wang G; Zhai X; Hu Y; Gao D; Ma L; Yao J; Tian X
Cell Death Dis; 2014 Apr; 5(4):e1164. PubMed ID: 24722289
[TBL] [Abstract][Full Text] [Related]
6. Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly.
Rajendran P; Delage B; Dashwood WM; Yu TW; Wuth B; Williams DE; Ho E; Dashwood RH
Mol Cancer; 2011 May; 10():68. PubMed ID: 21624135
[TBL] [Abstract][Full Text] [Related]
7. Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species.
Singh SV; Srivastava SK; Choi S; Lew KL; Antosiewicz J; Xiao D; Zeng Y; Watkins SC; Johnson CS; Trump DL; Lee YJ; Xiao H; Herman-Antosiewicz A
J Biol Chem; 2005 May; 280(20):19911-24. PubMed ID: 15764812
[TBL] [Abstract][Full Text] [Related]
8. Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc.
Pinton P; Rimessi A; Marchi S; Orsini F; Migliaccio E; Giorgio M; Contursi C; Minucci S; Mantovani F; Wieckowski MR; Del Sal G; Pelicci PG; Rizzuto R
Science; 2007 Feb; 315(5812):659-63. PubMed ID: 17272725
[TBL] [Abstract][Full Text] [Related]
9. The p66(Shc) redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells.
Natalicchio A; Tortosa F; Labarbuta R; Biondi G; Marrano N; Carchia E; Leonardini A; Cignarelli A; Bugliani M; Marchetti P; Fadini GP; Giorgio M; Avogaro A; Perrini S; Laviola L; Giorgino F
Diabetologia; 2015 Jun; 58(6):1260-71. PubMed ID: 25810038
[TBL] [Abstract][Full Text] [Related]
10. p66Shc mediates high-glucose and angiotensin II-induced oxidative stress renal tubular injury via mitochondrial-dependent apoptotic pathway.
Sun L; Xiao L; Nie J; Liu FY; Ling GH; Zhu XJ; Tang WB; Chen WC; Xia YC; Zhan M; Ma MM; Peng YM; Liu H; Liu YH; Kanwar YS
Am J Physiol Renal Physiol; 2010 Nov; 299(5):F1014-25. PubMed ID: 20739391
[TBL] [Abstract][Full Text] [Related]
11. p53-p66(shc)/miR-21-Sod2 signaling is critical for the inhibitory effect of betulinic acid on hepatocellular carcinoma.
Yang J; Qiu B; Li X; Zhang H; Liu W
Toxicol Lett; 2015 Nov; 238(3):1-10. PubMed ID: 26222667
[TBL] [Abstract][Full Text] [Related]
12. D,L-Sulforaphane-induced cell death in human prostate cancer cells is regulated by inhibitor of apoptosis family proteins and Apaf-1.
Choi S; Lew KL; Xiao H; Herman-Antosiewicz A; Xiao D; Brown CK; Singh SV
Carcinogenesis; 2007 Jan; 28(1):151-62. PubMed ID: 16920735
[TBL] [Abstract][Full Text] [Related]
13. Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species.
Vikram A; Kim YR; Kumar S; Naqvi A; Hoffman TA; Kumar A; Miller FJ; Kim CS; Irani K
Arterioscler Thromb Vasc Biol; 2014 Oct; 34(10):2301-9. PubMed ID: 25147340
[TBL] [Abstract][Full Text] [Related]
14. Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species.
Hahm ER; Moura MB; Kelley EE; Van Houten B; Shiva S; Singh SV
PLoS One; 2011; 6(8):e23354. PubMed ID: 21853114
[TBL] [Abstract][Full Text] [Related]
15. Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells.
Shi Y; Cosentino F; Camici GG; Akhmedov A; Vanhoutte PM; Tanner FC; Lüscher TF
Arterioscler Thromb Vasc Biol; 2011 Sep; 31(9):2090-7. PubMed ID: 21817106
[TBL] [Abstract][Full Text] [Related]
16. Cellular responses to cancer chemopreventive agent D,L-sulforaphane in human prostate cancer cells are initiated by mitochondrial reactive oxygen species.
Xiao D; Powolny AA; Antosiewicz J; Hahm ER; Bommareddy A; Zeng Y; Desai D; Amin S; Herman-Antosiewicz A; Singh SV
Pharm Res; 2009 Jul; 26(7):1729-38. PubMed ID: 19384467
[TBL] [Abstract][Full Text] [Related]
17. Targeting prolyl-isomerase Pin1 prevents mitochondrial oxidative stress and vascular dysfunction: insights in patients with diabetes.
Paneni F; Costantino S; Castello L; Battista R; Capretti G; Chiandotto S; D'Amario D; Scavone G; Villano A; Rustighi A; Crea F; Pitocco D; Lanza G; Volpe M; Del Sal G; Lüscher TF; Cosentino F
Eur Heart J; 2015 Apr; 36(13):817-28. PubMed ID: 24801072
[TBL] [Abstract][Full Text] [Related]
18. Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent.
Choi S; Singh SV
Cancer Res; 2005 Mar; 65(5):2035-43. PubMed ID: 15753404
[TBL] [Abstract][Full Text] [Related]
19. Gene silencing of the mitochondrial adaptor p66(Shc) suppresses vascular hyperglycemic memory in diabetes.
Paneni F; Mocharla P; Akhmedov A; Costantino S; Osto E; Volpe M; Lüscher TF; Cosentino F
Circ Res; 2012 Jul; 111(3):278-89. PubMed ID: 22693349
[TBL] [Abstract][Full Text] [Related]
20. TNFα signals via p66(Shc) to induce E-Selectin, promote leukocyte transmigration and enhance permeability in human endothelial cells.
Laviola L; Orlando MR; Incalza MA; Caccioppoli C; Melchiorre M; Leonardini A; Cignarelli A; Tortosa F; Labarbuta R; Martemucci S; Pacelli C; Cocco T; Perrini S; Natalicchio A; Giorgino F
PLoS One; 2013; 8(12):e81930. PubMed ID: 24349153
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
