These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 21958292)

  • 1. Synthesis and biochemical evaluation of δ(2)-isoxazoline derivatives as DNA methyltransferase 1 inhibitors.
    Castellano S; Kuck D; Viviano M; Yoo J; López-Vallejo F; Conti P; Tamborini L; Pinto A; Medina-Franco JL; Sbardella G
    J Med Chem; 2011 Nov; 54(21):7663-77. PubMed ID: 21958292
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Constrained analogues of procaine as novel small molecule inhibitors of DNA methyltransferase-1.
    Castellano S; Kuck D; Sala M; Novellino E; Lyko F; Sbardella G
    J Med Chem; 2008 Apr; 51(7):2321-5. PubMed ID: 18345608
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rapid synthesis of new DNMT inhibitors derivatives of procainamide.
    Halby L; Champion C; Sénamaud-Beaufort C; Ajjan S; Drujon T; Rajavelu A; Ceccaldi A; Jurkowska R; Lequin O; Nelson WG; Guy A; Jeltsch A; Guianvarc'h D; Ferroud C; Arimondo PB
    Chembiochem; 2012 Jan; 13(1):157-65. PubMed ID: 22170584
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90.
    Gopalsamy A; Shi M; Golas J; Vogan E; Jacob J; Johnson M; Lee F; Nilakantan R; Petersen R; Svenson K; Chopra R; Tam MS; Wen Y; Ellingboe J; Arndt K; Boschelli F
    J Med Chem; 2008 Feb; 51(3):373-5. PubMed ID: 18197612
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of 3,5-diaryl isoxazoline/isoxazole linked 2,3-dihydroquinazolinone hybrids as anticancer agents.
    Kamal A; Bharathi EV; Reddy JS; Ramaiah MJ; Dastagiri D; Reddy MK; Viswanath A; Reddy TL; Shaik TB; Pushpavalli SN; Bhadra MP
    Eur J Med Chem; 2011 Feb; 46(2):691-703. PubMed ID: 21194809
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of novel benzoxanthone analogues as non-Camptothecin topoisomerase I inhibitors.
    Cheng P; Zhu L; Guo W; Liu W; Yao J; Dong G; Zhang Y; Zhuang C; Sheng C; Miao Z; Zhang W
    J Enzyme Inhib Med Chem; 2012 Jun; 27(3):437-42. PubMed ID: 21770860
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel 3,4-isoxazolediamides as potent inhibitors of chaperone heat shock protein 90.
    Baruchello R; Simoni D; Grisolia G; Barbato G; Marchetti P; Rondanin R; Mangiola S; Giannini G; Brunetti T; Alloatti D; Gallo G; Ciacci A; Vesci L; Castorina M; Milazzo FM; Cervoni ML; Guglielmi MB; Barbarino M; Foderà R; Pisano C; Cabri W
    J Med Chem; 2011 Dec; 54(24):8592-604. PubMed ID: 22066525
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and evaluation of analogues of N-phthaloyl-l-tryptophan (RG108) as inhibitors of DNA methyltransferase 1.
    Asgatay S; Champion C; Marloie G; Drujon T; Senamaud-Beaufort C; Ceccaldi A; Erdmann A; Rajavelu A; Schambel P; Jeltsch A; Lequin O; Karoyan P; Arimondo PB; Guianvarc'h D
    J Med Chem; 2014 Jan; 57(2):421-34. PubMed ID: 24328113
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase.
    Shi J; McAtee JJ; Schlueter Wirtz S; Tharnish P; Juodawlkis A; Liotta DC; Schinazi RF
    J Med Chem; 1999 Mar; 42(5):859-67. PubMed ID: 10072683
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, molecular docking and evaluation of thiazolyl-pyrazoline derivatives as EGFR TK inhibitors and potential anticancer agents.
    Lv PC; Li DD; Li QS; Lu X; Xiao ZP; Zhu HL
    Bioorg Med Chem Lett; 2011 Sep; 21(18):5374-7. PubMed ID: 21802290
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular modeling and molecular dynamics studies of hydralazine with human DNA methyltransferase 1.
    Singh N; Dueñas-González A; Lyko F; Medina-Franco JL
    ChemMedChem; 2009 May; 4(5):792-9. PubMed ID: 19322801
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and anticancer activity of novel spiro-isoxazoline and spiro-isoxazolidine derivatives of α-santonin.
    Khazir J; Singh PP; Reddy DM; Hyder I; Shafi S; Sawant SD; Chashoo G; Mahajan A; Alam MS; Saxena AK; Arvinda S; Gupta BD; Kumar HM
    Eur J Med Chem; 2013 May; 63():279-89. PubMed ID: 23501113
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation.
    Kuck D; Singh N; Lyko F; Medina-Franco JL
    Bioorg Med Chem; 2010 Jan; 18(2):822-9. PubMed ID: 20006515
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, inhibitory activity, and binding mode study of novel DNA methyltransferase 1 inhibitors.
    Suzuki T; Tanaka R; Hamada S; Nakagawa H; Miyata N
    Bioorg Med Chem Lett; 2010 Feb; 20(3):1124-7. PubMed ID: 20056538
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and antiproliferative evaluation of 23-hydroxybetulinic acid derivatives.
    Lan P; Wang J; Zhang DM; Shu C; Cao HH; Sun PH; Wu XM; Ye WC; Chen WM
    Eur J Med Chem; 2011 Jun; 46(6):2490-502. PubMed ID: 21496972
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of new isoxazoline derivatives from harmine and evaluation of their anti-Alzheimer, anti-cancer and anti-inflammatory activities.
    Filali I; Bouajila J; Znati M; Bousejra-El Garah F; Ben Jannet H
    J Enzyme Inhib Med Chem; 2015 Jun; 30(3):371-6. PubMed ID: 25068731
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of novel beta-carbolines with efficient DNA-binding capacity and potent cytotoxicity.
    Chen Z; Cao R; Shi B; Yi W; Yu L; Song H; Ren Z; Peng W
    Bioorg Med Chem Lett; 2010 Jul; 20(13):3876-9. PubMed ID: 20627721
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, characterization, interaction with DNA, and cytotoxic effect in vitro of new mono- and dinuclear Pd(II) and Pt(II) complexes with benzo[d]thiazol-2-amine as the primary ligand.
    Gao E; Liu L; Zhu M; Huang Y; Guan F; Gao X; Zhang M; Wang L; Zhang W; Sun Y
    Inorg Chem; 2011 Jun; 50(11):4732-41. PubMed ID: 21520903
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antiproliferative novel isoxazoles: modeling, virtual screening, synthesis, and bioactivity evaluation.
    Tzanetou E; Liekens S; Kasiotis KM; Melagraki G; Afantitis A; Fokialakis N; Haroutounian SA
    Eur J Med Chem; 2014 Jun; 81():139-49. PubMed ID: 24836066
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and biological evaluation of thiazolidinone derivatives as potential EGFR and HER-2 kinase inhibitors.
    Lv PC; Zhou CF; Chen J; Liu PG; Wang KR; Mao WJ; Li HQ; Yang Y; Xiong J; Zhu HL
    Bioorg Med Chem; 2010 Jan; 18(1):314-9. PubMed ID: 19914835
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.