These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

100 related articles for article (PubMed ID: 21958719)

  • 1. Efavirenz and 8-hydroxyefavirenz induce cell death via a JNK- and BimEL-dependent mechanism in primary human hepatocytes.
    Bumpus NN
    Toxicol Appl Pharmacol; 2011 Dec; 257(2):227-34. PubMed ID: 21958719
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Efavirenz and Efavirenz-like Compounds Activate Human, Murine, and Macaque Hepatic IRE1
    Heck CJS; Hamlin AN; Bumpus NN
    Mol Pharmacol; 2019 Feb; 95(2):183-195. PubMed ID: 30442673
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dual regulation of hepatocyte apoptosis by reactive oxygen species: Increases in transcriptional expression and decreases in proteasomal degradation of BimEL.
    Ishihara Y; Takeuchi K; Ito F; Shimamoto N
    J Cell Physiol; 2011 Apr; 226(4):1007-16. PubMed ID: 20857401
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Probing Ligand Structure-Activity Relationships in Pregnane X Receptor (PXR): Efavirenz and 8-Hydroxyefavirenz Exhibit Divergence in Activation.
    Narayanan B; Lade JM; Heck CJS; Dietz KD; Wade H; Bumpus NN
    ChemMedChem; 2018 Apr; 13(7):736-747. PubMed ID: 29430850
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BimEL up-regulation potentiates AIF translocation and cell death in response to MPTP.
    Liou AK; Zhou Z; Pei W; Lim TM; Yin XM; Chen J
    FASEB J; 2005 Aug; 19(10):1350-2. PubMed ID: 15941767
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of Rac GTPase triggers a c-Jun- and Bim-dependent mitochondrial apoptotic cascade in cerebellar granule neurons.
    Le SS; Loucks FA; Udo H; Richardson-Burns S; Phelps RA; Bouchard RJ; Barth H; Aktories K; Tyler KL; Kandel ER; Heidenreich KA; Linseman DA
    J Neurochem; 2005 Aug; 94(4):1025-39. PubMed ID: 16092944
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase.
    Nakagawa H; Hirata Y; Takeda K; Hayakawa Y; Sato T; Kinoshita H; Sakamoto K; Nakata W; Hikiba Y; Omata M; Yoshida H; Koike K; Ichijo H; Maeda S
    Hepatology; 2011 Jul; 54(1):185-95. PubMed ID: 21488081
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis.
    Malhi H; Bronk SF; Werneburg NW; Gores GJ
    J Biol Chem; 2006 Apr; 281(17):12093-101. PubMed ID: 16505490
    [TBL] [Abstract][Full Text] [Related]  

  • 9. P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK.
    Fan S; Qi M; Yu Y; Li L; Yao G; Tashiro S; Onodera S; Ikejima T
    Free Radic Res; 2012 Mar; 46(3):310-9. PubMed ID: 22283740
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway.
    Gao Y; Signore AP; Yin W; Cao G; Yin XM; Sun F; Luo Y; Graham SH; Chen J
    J Cereb Blood Flow Metab; 2005 Jun; 25(6):694-712. PubMed ID: 15716857
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ceramide promotes apoptosis in lung cancer-derived A549 cells by a mechanism involving c-Jun NH2-terminal kinase.
    Kurinna SM; Tsao CC; Nica AF; Jiffar T; Ruvolo PP
    Cancer Res; 2004 Nov; 64(21):7852-6. PubMed ID: 15520191
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner.
    Schmich K; Schlatter R; Corazza N; Sá Ferreira K; Ederer M; Brunner T; Borner C; Merfort I
    Hepatology; 2011 Jan; 53(1):282-92. PubMed ID: 20872776
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity.
    Win S; Than TA; Le BH; García-Ruiz C; Fernandez-Checa JC; Kaplowitz N
    J Hepatol; 2015 Jun; 62(6):1367-74. PubMed ID: 25666017
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oxidant-induced hepatocyte injury from menadione is regulated by ERK and AP-1 signaling.
    Czaja MJ; Liu H; Wang Y
    Hepatology; 2003 Jun; 37(6):1405-13. PubMed ID: 12774020
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chronic high-dose morphine treatment promotes SH-SY5Y cell apoptosis via c-Jun N-terminal kinase-mediated activation of mitochondria-dependent pathway.
    Lin X; Wang YJ; Li Q; Hou YY; Hong MH; Cao YL; Chi ZQ; Liu JG
    FEBS J; 2009 Apr; 276(7):2022-36. PubMed ID: 19292871
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ribotoxic stress sensitizes glioblastoma cells to death receptor induced apoptosis: requirements for c-Jun NH2-terminal kinase and Bim.
    Xia S; Li Y; Rosen EM; Laterra J
    Mol Cancer Res; 2007 Aug; 5(8):783-92. PubMed ID: 17699104
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatocyte autophagy is linked to C/EBP-homologous protein, Bcl2-interacting mediator of cell death, and BH3-interacting domain death agonist gene expression.
    Zhang J; Singh N; Robinson-Taylor KS; Dorsett-Martin WA; Morris MW; Earl TM; Anderson CD
    J Surg Res; 2015 May; 195(2):588-95. PubMed ID: 25772147
    [TBL] [Abstract][Full Text] [Related]  

  • 18. JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity.
    Litwak SA; Pang L; Galic S; Igoillo-Esteve M; Stanley WJ; Turatsinze JV; Loh K; Thomas HE; Sharma A; Trepo E; Moreno C; Gough DJ; Eizirik DL; de Haan JB; Gurzov EN
    Diabetes; 2017 Dec; 66(12):2973-2986. PubMed ID: 28928277
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of the JNK pathway promotes phosphorylation and degradation of BimEL--a novel mechanism of chemoresistance in T-cell acute lymphoblastic leukemia.
    Leung KT; Li KK; Sun SS; Chan PK; Ooi VE; Chiu LC
    Carcinogenesis; 2008 Mar; 29(3):544-51. PubMed ID: 18174237
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Heroin activates Bim via c-Jun N-terminal kinase/c-Jun pathway to mediate neuronal apoptosis.
    Tan M; Li Z; Ma S; Luo J; Xu S; Lu A; Gan W; Su P; Lin H; Li S; Lai B
    Neuroscience; 2013 Mar; 233():1-8. PubMed ID: 23262244
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.