BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 21958855)

  • 1. Radiotracer properties determined by high performance liquid chromatography: a potential tool for brain radiotracer discovery.
    Tavares AA; Lewsey J; Dewar D; Pimlott SL
    Nucl Med Biol; 2012 Jan; 39(1):127-35. PubMed ID: 21958855
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lipophilic and polar interaction forces between acidic drugs and membrane phospholipids encoded in IAM-HPLC indexes: their role in membrane partition and relationships with BBB permeation data.
    Grumetto L; Carpentiero C; Di Vaio P; Frecentese F; Barbato F
    J Pharm Biomed Anal; 2013 Mar; 75():165-72. PubMed ID: 23261809
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Radiotracer development in psychiatry.
    Pimlott SL
    Nucl Med Commun; 2005 Mar; 26(3):183-8. PubMed ID: 15722898
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Efficiency gains in tracer identification for nuclear imaging: can in vivo LC-MS/MS evaluation of small molecules screen for successful PET tracers?
    Joshi EM; Need A; Schaus J; Chen Z; Benesh D; Mitch C; Morton S; Raub TJ; Phebus L; Barth V
    ACS Chem Neurosci; 2014 Dec; 5(12):1154-63. PubMed ID: 25247893
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Validation of in vitro cell-based human blood-brain barrier model using clinical positron emission tomography radioligands to predict in vivo human brain penetration.
    Mabondzo A; Bottlaender M; Guyot AC; Tsaouin K; Deverre JR; Balimane PV
    Mol Pharm; 2010 Oct; 7(5):1805-15. PubMed ID: 20795735
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A rapid vesicle electrokinetic chromatography method for the in vitro prediction of non-specific binding for potential PET ligands.
    Jiang Z; Reilly J; Everatt B; Briard E
    J Pharm Biomed Anal; 2011 Mar; 54(4):722-9. PubMed ID: 21126842
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of plasma protein binding on in vivo activity and brain penetration of glycine/NMDA receptor antagonists.
    Rowley M; Kulagowski JJ; Watt AP; Rathbone D; Stevenson GI; Carling RW; Baker R; Marshall GR; Kemp JA; Foster AC; Grimwood S; Hargreaves R; Hurley C; Saywell KL; Tricklebank MD; Leeson PD
    J Med Chem; 1997 Dec; 40(25):4053-68. PubMed ID: 9406596
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vivo evaluation in rats of [(18)F]1-(2-fluoroethyl)-4-[(4-cyanophenoxy)methyl]piperidine as a potential radiotracer for PET assessment of CNS sigma-1 receptors.
    Waterhouse RN; Chang RC; Zhao J; Carambot PE
    Nucl Med Biol; 2006 Feb; 33(2):211-5. PubMed ID: 16546675
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expanding LogP: Present possibilities.
    Vraka C; Mijailovic S; Fröhlich V; Zeilinger M; Klebermass EM; Wadsak W; Wagner KH; Hacker M; Mitterhauser M
    Nucl Med Biol; 2018 Mar; 58():20-32. PubMed ID: 29309919
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Strategies for designing novel positron emission tomography (PET) radiotracers to cross the blood-brain barrier.
    Lindberg A; Chassé M; Varlow C; Pees A; Vasdev N
    J Labelled Comp Radiopharm; 2023 Jul; 66(9):205-221. PubMed ID: 36815704
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Radiosynthesis and evaluation of [11C]-(+)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol as a potential radiotracer for in vivo imaging of the dopamine D2 high-affinity state with positron emission tomography.
    Wilson AA; McCormick P; Kapur S; Willeit M; Garcia A; Hussey D; Houle S; Seeman P; Ginovart N
    J Med Chem; 2005 Jun; 48(12):4153-60. PubMed ID: 15943487
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lipophilic and electrostatic forces encoded in IAM-HPLC indexes of basic drugs: their role in membrane partition and their relationships with BBB passage data.
    Grumetto L; Carpentiero C; Barbato F
    Eur J Pharm Sci; 2012 Apr; 45(5):685-92. PubMed ID: 22306648
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design of brain imaging agents for positron emission tomography: do large bioconjugates provide an opportunity for in vivo brain imaging?
    Schirrmacher R; Bernard-Gauthier V; Reader A; Soucy JP; Schirrmacher E; Wängler B; Wängler C
    Future Med Chem; 2013 Sep; 5(14):1621-34. PubMed ID: 24047268
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ¹²³I-NKJ64: a novel single photon emission computed tomography radiotracer for imaging the noradrenaline transporter in brain.
    Tavares AA; Jobson NK; Dewar D; Sutherland A; Pimlott SL
    Synapse; 2011 Jul; 65(7):658-67. PubMed ID: 21157929
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Use of biopartitioning micellar chromatography and RP-HPLC for the determination of blood-brain barrier penetration of α-adrenergic/imidazoline receptor ligands, and QSPR analysis.
    Vucicevic J; Popovic M; Nikolic K; Filipic S; Obradovic D; Agbaba D
    SAR QSAR Environ Res; 2017 Mar; 28(3):235-252. PubMed ID: 28332439
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vivo evaluation of 18F-MNI698: an 18F-labeled radiotracer for imaging of serotonin 4 receptors in brain.
    Tavares AA; Caillé F; Barret O; Papin C; Lee H; Morley TJ; Fowles K; Holden D; Seibyl JP; Alagille D; Tamagnan GD
    J Nucl Med; 2014 May; 55(5):858-64. PubMed ID: 24686782
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptors.
    Wilson AA; Garcia A; Parkes J; McCormick P; Stephenson KA; Houle S; Vasdev N
    Nucl Med Biol; 2008 Apr; 35(3):305-14. PubMed ID: 18355686
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Use of a physiologically based pharmacokinetic model to study the time to reach brain equilibrium: an experimental analysis of the role of blood-brain barrier permeability, plasma protein binding, and brain tissue binding.
    Liu X; Smith BJ; Chen C; Callegari E; Becker SL; Chen X; Cianfrogna J; Doran AC; Doran SD; Gibbs JP; Hosea N; Liu J; Nelson FR; Szewc MA; Van Deusen J
    J Pharmacol Exp Ther; 2005 Jun; 313(3):1254-62. PubMed ID: 15743928
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacokinetics, brain distribution and plasma protein binding of carbamazepine and nine derivatives: new set of data for predictive in silico ADME models.
    Fortuna A; Alves G; Soares-da-Silva P; Falcão A
    Epilepsy Res; 2013 Nov; 107(1-2):37-50. PubMed ID: 24050973
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Brain SPECT imaging and whole-body biodistribution with [(123)I]ADAM - a serotonin transporter radiotracer in healthy human subjects.
    Lin KJ; Liu CY; Wey SP; Hsiao IT; Wu J; Fu YK; Yen TC
    Nucl Med Biol; 2006 Feb; 33(2):193-202. PubMed ID: 16546673
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.