BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

97 related articles for article (PubMed ID: 21964185)

  • 1. Discovery of pyridine-2-ones as novel class of multidrug resistance (MDR) modulators: first structure-activity relationships.
    Krawczyk S; Otto M; Otto A; Coburger C; Krug M; Seifert M; Tell V; Molnár J; Hilgeroth A
    Bioorg Med Chem; 2011 Nov; 19(21):6309-15. PubMed ID: 21964185
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Development of small-molecule P-gp inhibitors of the N-benzyl 1,4-dihydropyridine type: novel aspects in SAR and bioanalytical evaluation of multidrug resistance (MDR) reversal properties.
    Baumert C; Günthel M; Krawczyk S; Hemmer M; Wersig T; Langner A; Molnár J; Lage H; Hilgeroth A
    Bioorg Med Chem; 2013 Jan; 21(1):166-77. PubMed ID: 23199479
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multidrug resistance reversal properties and cytotoxic evaluation of representatives of a novel class of HIV-1 protease inhibitors.
    Coburger C; Lage H; Molnár J; Langner A; Hilgeroth A
    J Pharm Pharmacol; 2010 Dec; 62(12):1704-10. PubMed ID: 21054396
    [TBL] [Abstract][Full Text] [Related]  

  • 4. First biological evaluation of developed 3-benzyloxyfluorenes as novel class of MDR modulators.
    Krug M; Voigt B; Baumert C; Lüpken R; Molnár J; Hilgeroth A
    Eur J Med Chem; 2010 Jun; 45(6):2683-8. PubMed ID: 20207048
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lathyrane diterpenes from Euphorbia lathyris as modulators of multidrug resistance and their crystal structures.
    Jiao W; Dong W; Li Z; Deng M; Lu R
    Bioorg Med Chem; 2009 Jul; 17(13):4786-92. PubMed ID: 19443229
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Jatrophane diterpenes as modulators of multidrug resistance. Advances of structure-activity relationships and discovery of the potent lead pepluanin A.
    Corea G; Fattorusso E; Lanzotti V; Motti R; Simon PN; Dumontet C; Di Pietro A
    J Med Chem; 2004 Feb; 47(4):988-92. PubMed ID: 14761200
    [TBL] [Abstract][Full Text] [Related]  

  • 7. New 1,3-dioxolane and 1,3-dioxane derivatives as effective modulators to overcome multidrug resistance.
    Schmidt M; Ungvári J; Glöde J; Dobner B; Langner A
    Bioorg Med Chem; 2007 Mar; 15(6):2283-97. PubMed ID: 17276076
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhancing macrocyclic diterpenes as multidrug-resistance reversers: structure-activity studies on jolkinol D derivatives.
    Reis M; Ferreira RJ; Santos MM; dos Santos DJ; Molnár J; Ferreira MJ
    J Med Chem; 2013 Feb; 56(3):748-60. PubMed ID: 23336337
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 3'-O, 4'-O-aromatic acyl substituted 7,8-pyranocoumarins: a new class of P-glycoprotein modulators.
    Shen X; Chen G; Zhu G; Cai J; Wang L; Hu Y; Fong WF
    J Pharm Pharmacol; 2012 Jan; 64(1):90-100. PubMed ID: 22150676
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Acridones circumvent P-glycoprotein-associated multidrug resistance (MDR) in cancer cells.
    Gopinath VS; Thimmaiah P; Thimmaiah KN
    Bioorg Med Chem; 2008 Jan; 16(1):474-87. PubMed ID: 17933543
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recent advances in the discovery of flavonoids and analogs with high-affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance.
    Boumendjel A; Di Pietro A; Dumontet C; Barron D
    Med Res Rev; 2002 Sep; 22(5):512-29. PubMed ID: 12210557
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dregamine and tabernaemontanine derivatives as ABCB1 modulators on resistant cancer cells.
    Paterna A; Kincses A; Spengler G; Mulhovo S; Molnár J; Ferreira MU
    Eur J Med Chem; 2017 Mar; 128():247-257. PubMed ID: 28189906
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reversal of P-gp mediated multidrug resistance in-vitro and in-vivo by FG020318.
    Chen LM; Liang YJ; Ruan JW; Ding Y; Wang XW; Shi Z; Gu LQ; Yang XP; Fu LW
    J Pharm Pharmacol; 2004 Aug; 56(8):1061-6. PubMed ID: 15285852
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity relationships of novel N-acyloxy-1,4-dihydropyridines as P-glycoprotein inhibitors.
    Voigt B; Coburger C; Monár J; Hilgeroth A
    Bioorg Med Chem; 2007 Aug; 15(15):5110-3. PubMed ID: 17533131
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance.
    Newman MJ; Rodarte JC; Benbatoul KD; Romano SJ; Zhang C; Krane S; Moran EJ; Uyeda RT; Dixon R; Guns ES; Mayer LD
    Cancer Res; 2000 Jun; 60(11):2964-72. PubMed ID: 10850444
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Overcoming human P-glycoprotein-dependent multidrug resistance with novel dihydro-β-agarofuran sesquiterpenes.
    Perestelo NR; Sánchez-Cañete MP; Gamarro F; Jiménez IA; Castanys S; Bazzocchi IL
    Eur J Med Chem; 2011 Oct; 46(10):4915-23. PubMed ID: 21856049
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prolongation of pentoxifylline aliphatic side chain positively affects the reversal of P-glycoprotein-mediated multidrug resistance in L1210/VCR line cells.
    Docolomanský P; Fialová I; Barancík M; Rybár A; Breier A
    Gen Physiol Biophys; 2005 Dec; 24(4):461-6. PubMed ID: 16474189
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of pyrazole-based hybrid molecules: search for potent multidrug resistance modulators.
    Singh P; Paul K; Holzer W
    Bioorg Med Chem; 2006 Jul; 14(14):5061-71. PubMed ID: 16554161
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Anticancer multidrug resistance mediated by MRP1: recent advances in the discovery of reversal agents.
    Boumendjel A; Baubichon-Cortay H; Trompier D; Perrotton T; Di Pietro A
    Med Res Rev; 2005 Jul; 25(4):453-72. PubMed ID: 15834856
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Substituted tetrahydroisoquinoline compound B3 inhibited P-glycoprotein-mediated multidrug resistance in-vitro and in-vivo.
    Fang W; Li Y; Cai Y; Kang K; Yan F; Liu G; Huang W
    J Pharm Pharmacol; 2007 Dec; 59(12):1649-55. PubMed ID: 18053326
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.