BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 21965271)

  • 1. Graded activation of the MEK1/MT1-MMP axis determines renal epithelial cell tumor phenotype.
    Mahimkar R; Alfonso-Jaume MA; Cape LM; Dahiya R; Lovett DH
    Carcinogenesis; 2011 Dec; 32(12):1806-14. PubMed ID: 21965271
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tumor cell invasion of von Hippel Lindau renal cell carcinoma cells is mediated by membrane type-1 matrix metalloproteinase.
    Petrella BL; Brinckerhoff CE
    Mol Cancer; 2006 Dec; 5():66. PubMed ID: 17140440
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Constitutively active mitogen-activated protein kinase kinase MEK1 disrupts morphogenesis and induces an invasive phenotype in Madin-Darby canine kidney epithelial cells.
    Montesano R; Soriano JV; Hosseini G; Pepper MS; Schramek H
    Cell Growth Differ; 1999 May; 10(5):317-32. PubMed ID: 10359013
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of active MEK1-ERK1/2 restores epithelial phenotype and morphogenesis in transdifferentiated MDCK cells.
    Schramek H; Feifel E; Marschitz I; Golochtchapova N; Gstraunthaler G; Montesano R
    Am J Physiol Cell Physiol; 2003 Sep; 285(3):C652-61. PubMed ID: 12900389
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Constitutively active mutant of the mitogen-activated protein kinase kinase MEK1 induces epithelial dedifferentiation and growth inhibition in madin-darby canine kidney-C7 cells.
    Schramek H; Feifel E; Healy E; Pollack V
    J Biol Chem; 1997 Apr; 272(17):11426-33. PubMed ID: 9111053
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MT1-MMP Activation of TGF-β Signaling Enables Intercellular Activation of an Epithelial-mesenchymal Transition Program in Cancer.
    Nguyen HL; Kadam P; Helkin A; Cao K; Wu S; Samara GJ; Zhang Q; Zucker S; Cao J
    Curr Cancer Drug Targets; 2016; 16(7):618-30. PubMed ID: 26881932
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cocoa procyanidins inhibit expression and activation of MMP-2 in vascular smooth muscle cells by direct inhibition of MEK and MT1-MMP activities.
    Lee KW; Kang NJ; Oak MH; Hwang MK; Kim JH; Schini-Kerth VB; Lee HJ
    Cardiovasc Res; 2008 Jul; 79(1):34-41. PubMed ID: 18310679
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Timp-2 binding with cellular MT1-MMP stimulates invasion-promoting MEK/ERK signaling in cancer cells.
    Sounni NE; Rozanov DV; Remacle AG; Golubkov VS; Noel A; Strongin AY
    Int J Cancer; 2010 Mar; 126(5):1067-78. PubMed ID: 19551841
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Membrane type 1-matrix metalloproteinase induces epithelial-to-mesenchymal transition in esophageal squamous cell carcinoma: Observations from clinical and in vitro analyses.
    Pang L; Li Q; Li S; He J; Cao W; Lan J; Sun B; Zou H; Wang C; Liu R; Wei C; Wei Y; Qi Y; Hu J; Liang W; Zhang WJ; Wan M; Li F
    Sci Rep; 2016 Feb; 6():22179. PubMed ID: 26916665
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism.
    D'Alessio S; Ferrari G; Cinnante K; Scheerer W; Galloway AC; Roses DF; Rozanov DV; Remacle AG; Oh ES; Shiryaev SA; Strongin AY; Pintucci G; Mignatti P
    J Biol Chem; 2008 Jan; 283(1):87-99. PubMed ID: 17991754
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression of metastasis-associated mts1 gene is co-induced with membrane type-1 matrix metalloproteinase (MT1-MMP) during oncogenic transformation and tubular formation of Madin Darby canine kidney (MDCK) epithelial cells.
    Miyamori H; Hasegawa K; Kim KR; Sato H
    Clin Exp Metastasis; 2000; 18(1):51-6. PubMed ID: 11206838
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Membrane type 1 matrix metalloproteinase regulates collagen-dependent mitogen-activated protein/extracellular signal-related kinase activation and cell migration.
    Takino T; Miyamori H; Watanabe Y; Yoshioka K; Seiki M; Sato H
    Cancer Res; 2004 Feb; 64(3):1044-9. PubMed ID: 14871836
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pancreatic cancer cells respond to type I collagen by inducing snail expression to promote membrane type 1 matrix metalloproteinase-dependent collagen invasion.
    Shields MA; Dangi-Garimella S; Krantz SB; Bentrem DJ; Munshi HG
    J Biol Chem; 2011 Mar; 286(12):10495-504. PubMed ID: 21288898
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transformation of epithelial Madin-Darby canine kidney cells with p60(v-src) induces expression of membrane-type 1 matrix metalloproteinase and invasiveness.
    Kadono Y; Okada Y; Namiki M; Seiki M; Sato H
    Cancer Res; 1998 May; 58(10):2240-4. PubMed ID: 9605772
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells.
    Pulyaeva H; Bueno J; Polette M; Birembaut P; Sato H; Seiki M; Thompson EW
    Clin Exp Metastasis; 1997 Mar; 15(2):111-20. PubMed ID: 9062387
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PDGF-BB-induced MT1-MMP expression regulates proliferation and invasion of mesenchymal stem cells in 3-dimensional collagen via MEK/ERK1/2 and PI3K/AKT signaling.
    Sun X; Gao X; Zhou L; Sun L; Lu C
    Cell Signal; 2013 May; 25(5):1279-87. PubMed ID: 23415772
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
    Sakamoto A; Oda Y; Iwamoto Y; Tsuneyoshi M
    J Cancer Res Clin Oncol; 1999 Oct; 125(10):541-8. PubMed ID: 10473866
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TIMP-1 induces an EMT-like phenotypic conversion in MDCK cells independent of its MMP-inhibitory domain.
    Jung YS; Liu XW; Chirco R; Warner RB; Fridman R; Kim HR
    PLoS One; 2012; 7(6):e38773. PubMed ID: 22701711
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of MT1-MMP activity by β-catenin in MDCK non-cancer and HT1080 cancer cells.
    Liu P; Yang J; Pei J; Pei D; Wilson MJ
    J Cell Physiol; 2010 Nov; 225(3):810-21. PubMed ID: 20589835
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting a Designer TIMP-1 to the Cell Surface for Effective MT1-MMP Inhibition: A Potential Role for the Prion Protein in Renal Carcinoma Therapy.
    Jiang B; Liu J; Lee MH
    Molecules; 2019 Jan; 24(2):. PubMed ID: 30641935
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.