These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 21967057)

  • 1. The P-glycoprotein multidrug transporter.
    Sharom FJ
    Essays Biochem; 2011 Sep; 50(1):161-78. PubMed ID: 21967057
    [TBL] [Abstract][Full Text] [Related]  

  • 2. P-glycoprotein (ABCB1) interacts directly with lipid-based anti-cancer drugs and platelet-activating factors.
    Eckford PD; Sharom FJ
    Biochem Cell Biol; 2006 Dec; 84(6):1022-33. PubMed ID: 17215888
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Shedding light on drug transport: structure and function of the P-glycoprotein multidrug transporter (ABCB1).
    Sharom FJ
    Biochem Cell Biol; 2006 Dec; 84(6):979-92. PubMed ID: 17215884
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The reconstituted P-glycoprotein multidrug transporter is a flippase for glucosylceramide and other simple glycosphingolipids.
    Eckford PD; Sharom FJ
    Biochem J; 2005 Jul; 389(Pt 2):517-26. PubMed ID: 15799713
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulator-induced interference in functional cross talk between the substrate and the ATP sites of human P-glycoprotein.
    Maki N; Moitra K; Silver C; Ghosh P; Chattopadhyay A; Dey S
    Biochemistry; 2006 Feb; 45(8):2739-51. PubMed ID: 16489767
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interaction of the P-glycoprotein multidrug efflux pump with cholesterol: effects on ATPase activity, drug binding and transport.
    Eckford PD; Sharom FJ
    Biochemistry; 2008 Dec; 47(51):13686-98. PubMed ID: 19049391
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The membrane lipid environment modulates drug interactions with the P-glycoprotein multidrug transporter.
    Romsicki Y; Sharom FJ
    Biochemistry; 1999 May; 38(21):6887-96. PubMed ID: 10346910
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural flexibility of the linker region of human P-glycoprotein permits ATP hydrolysis and drug transport.
    Hrycyna CA; Airan LE; Germann UA; Ambudkar SV; Pastan I; Gottesman MM
    Biochemistry; 1998 Sep; 37(39):13660-73. PubMed ID: 9753453
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Complex Interplay between the P-Glycoprotein Multidrug Efflux Pump and the Membrane: Its Role in Modulating Protein Function.
    Sharom FJ
    Front Oncol; 2014; 4():41. PubMed ID: 24624364
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression and function of p-glycoprotein in normal tissues: effect on pharmacokinetics.
    Staud F; Ceckova M; Micuda S; Pavek P
    Methods Mol Biol; 2010; 596():199-222. PubMed ID: 19949926
    [TBL] [Abstract][Full Text] [Related]  

  • 11. P glycoprotein and the mechanism of multidrug resistance.
    Váradi A; Szakács G; Bakos E; Sarkadi B
    Novartis Found Symp; 2002; 243():54-65; discussion 65-8, 180-5. PubMed ID: 11990782
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proximity of the nucleotide binding domains of the P-glycoprotein multidrug transporter to the membrane surface: a resonance energy transfer study.
    Liu R; Sharom FJ
    Biochemistry; 1998 May; 37(18):6503-12. PubMed ID: 9572868
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Does inhibition of P-glycoprotein lead to drug-drug interactions?
    Balayssac D; Authier N; Cayre A; Coudore F
    Toxicol Lett; 2005 Apr; 156(3):319-29. PubMed ID: 15763631
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Localization of multidrug transporter substrates within model membranes.
    Siarheyeva A; Lopez JJ; Glaubitz C
    Biochemistry; 2006 May; 45(19):6203-11. PubMed ID: 16681393
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, molecular structure, and validation of metalloprobes for assessment of MDR1 P-glycoprotein-mediated functional transport.
    Sivapackiam J; Harpstrite SE; Prior JL; Gu H; Rath NP; Sharma V
    Dalton Trans; 2010 Jul; 39(25):5842-50. PubMed ID: 20505882
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The power of the pump: mechanisms of action of P-glycoprotein (ABCB1).
    Ambudkar SV; Kim IW; Sauna ZE
    Eur J Pharm Sci; 2006 Apr; 27(5):392-400. PubMed ID: 16352426
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Drug transport by reconstituted P-glycoprotein in proteoliposomes. Effect of substrates and modulators, and dependence on bilayer phase state.
    Lu P; Liu R; Sharom FJ
    Eur J Biochem; 2001 Mar; 268(6):1687-97. PubMed ID: 11248688
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stimulation of P-glycoprotein ATPase by analogues of tetramethylrosamine: coupling of drug binding at the "R" site to the ATP hydrolysis transition state.
    Tombline G; Donnelly DJ; Holt JJ; You Y; Ye M; Gannon MK; Nygren CL; Detty MR
    Biochemistry; 2006 Jul; 45(26):8034-47. PubMed ID: 16800628
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A single amino acid residue contributes to distinct mechanisms of inhibition of the human multidrug transporter by stereoisomers of the dopamine receptor antagonist flupentixol.
    Dey S; Hafkemeyer P; Pastan I; Gottesman MM
    Biochemistry; 1999 May; 38(20):6630-9. PubMed ID: 10350482
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains.
    Liu R; Sharom FJ
    Biochemistry; 1996 Sep; 35(36):11865-73. PubMed ID: 8794769
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.