BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

111 related articles for article (PubMed ID: 21970435)

  • 1. Fibronectin promotes proplatelet formation in the human megakaryocytic cell line UT-7/TPO.
    Kawaguchi T; Hatano R; Yamaguchi K; Nawa K; Hashimoto R; Yokota H
    Cell Biol Int; 2012 Jan; 36(1):39-45. PubMed ID: 21970435
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potentiated activation of VLA-4 and VLA-5 accelerates proplatelet-like formation.
    Matsunaga T; Fukai F; Kameda T; Shide K; Shimoda H; Torii E; Kamiunten A; Sekine M; Yamamoto S; Hidaka T; Kubuki Y; Yokokura S; Uemura M; Matsuoka A; Waki F; Matsumoto K; Kanaji N; Ishii T; Imataki O; Dobashi H; Bandoh S; Shimoda K
    Ann Hematol; 2012 Oct; 91(10):1633-43. PubMed ID: 22644786
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fibronectin- and protein kinase C-mediated activation of ERK/MAPK are essential for proplateletlike formation.
    Jiang F; Jia Y; Cohen I
    Blood; 2002 May; 99(10):3579-84. PubMed ID: 11986211
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thrombopoietin induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in a human thrombopoietin-dependent cell line.
    Yamada M; Komatsu N; Okada K; Kato T; Miyazaki H; Miura Y
    Biochem Biophys Res Commun; 1995 Dec; 217(1):230-7. PubMed ID: 8526916
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A functional role of mitogen-activated protein kinases, erk1 and erk2, in the differentiation of a human leukemia cell line, UT-7/GM: a possible key factor for cell fate determination toward erythroid and megakaryocytic lineages.
    Uchida M; Kirito K; Shimizu R; Miura Y; Ozawa K; Komatsu N
    Int J Hematol; 2001 Jan; 73(1):78-83. PubMed ID: 11372759
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Platelet-derived growth factor receptors form complexes with neuropilin-1 during megakaryocytic differentiation of thrombopoietin-dependent UT-7/TPO cells.
    Ohsaka A; Hirota-Komatsu S; Araki M; Komatsu N
    Biochem Biophys Res Commun; 2015 Apr; 459(3):443-9. PubMed ID: 25744030
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PI3K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27(Kip1).
    Nakao T; Geddis AE; Fox NE; Kaushansky K
    Cell Cycle; 2008 Jan; 7(2):257-66. PubMed ID: 18256550
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of recombinant interleukin-6 and thrombopoietin on isolated guinea pig bone marrow megakaryocyte protein phosphorylation and proplatelet formation.
    Leven RM; Clark B; Tablin F
    Blood Cells Mol Dis; 1997 Aug; 23(2):252-68. PubMed ID: 9410469
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thrombopoietin (TPO) induces c-myc expression through a PI3K- and MAPK-dependent pathway that is not mediated by Akt, PKCzeta or mTOR in TPO-dependent cell lines and primary megakaryocytes.
    Chanprasert S; Geddis AE; Barroga C; Fox NE; Kaushansky K
    Cell Signal; 2006 Aug; 18(8):1212-8. PubMed ID: 16380230
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The human megakaryocytic cell line UT-7/TPO expresses functional platelet agonist signals mediated through GPVI and thromboxane receptor.
    Kawaguchi T; Hashimoto R; Yokota H
    Cell Biol Int; 2010 Sep; 34(9):943-9. PubMed ID: 20522022
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thrombopoietin-induced activation of the mitogen-activated protein kinase (MAPK) pathway in normal megakaryocytes: role in endomitosis.
    Rojnuckarin P; Drachman JG; Kaushansky K
    Blood; 1999 Aug; 94(4):1273-82. PubMed ID: 10438715
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Continuous expression of Bcl-xL protein during megakaryopoiesis is post-translationally regulated by thrombopoietin-mediated Akt activation, which prevents the cleavage of Bcl-xL.
    Kozuma Y; Kojima H; Yuki S; Suzuki H; Nagasawa T
    J Thromb Haemost; 2007 Jun; 5(6):1274-82. PubMed ID: 17389006
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition by Rho-kinase and protein kinase C of myosin phosphatase is involved in thrombin-induced shape change of megakaryocytic leukemia cell line UT-7/TPO.
    Yazaki A; Tamaru S; Sasaki Y; Komatsu N; Wada H; Shiku H; Nishikawa M
    Cell Signal; 2005 Mar; 17(3):321-30. PubMed ID: 15567063
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine- and integrin-mediated signals.
    Takizawa H; Eto K; Yoshikawa A; Nakauchi H; Takatsu K; Takaki S
    Exp Hematol; 2008 Jul; 36(7):897-906. PubMed ID: 18456388
    [TBL] [Abstract][Full Text] [Related]  

  • 15. hNUDC promotes the cell proliferation and differentiation in a leukemic cell line via activation of the thrombopoietin receptor (Mpl).
    Tang YS; Zhang YP; Xu P
    Leukemia; 2008 May; 22(5):1018-25. PubMed ID: 18288130
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neuropilin-1 forms complexes with vascular endothelial growth factor receptor-2 during megakaryocytic differentiation of UT-7/TPO cells.
    Ohsaka A; Hirota-Komatsu S; Shibata M; Komatsu N
    Biochem Biophys Res Commun; 2009 Dec; 390(4):1171-6. PubMed ID: 19857463
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thrombopoietin upregulates nucleolin mRNA and protein in thrombopoietin-dependent megakaryocytic cell line, UT-7/TPO.
    Ito T; Fujihara M; Oda A; Wakamoto S; Yamaguchi M; Komatsu N; Miyazaki H; Azuma H; Ikeda H; Ikebuchi K
    Mol Cell Biochem; 2003 May; 247(1-2):75-82. PubMed ID: 12841634
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of Gab proteins in phosphatidylinositol 3-kinase activation by thrombopoietin (Tpo).
    Bouscary D; Lecoq-Lafon C; Chrétien S; Zompi S; Fichelson S; Muller O; Porteu F; Dusanter-Fourt I; Gisselbrecht S; Mayeux P; Lacombe C
    Oncogene; 2001 Apr; 20(18):2197-204. PubMed ID: 11402314
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thrombopoietin enhances the alpha IIb beta 3-dependent adhesion of megakaryocytic cells to fibrinogen or fibronectin through PI 3 kinase.
    Zauli G; Bassini A; Vitale M; Gibellini D; Celeghini C; Caramelli E; Pierpaoli S; Guidotti L; Capitani S
    Blood; 1997 Feb; 89(3):883-95. PubMed ID: 9028319
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Fibronectin-induced proliferation in thyroid cells is mediated by alphavbeta3 integrin through Ras/Raf-1/MEK/ERK and calcium/CaMKII signals.
    Illario M; Cavallo AL; Monaco S; Di Vito E; Mueller F; Marzano LA; Troncone G; Fenzi G; Rossi G; Vitale M
    J Clin Endocrinol Metab; 2005 May; 90(5):2865-73. PubMed ID: 15687337
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.