These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 21972099)

  • 21. APP transgenic mouse models and their use in drug discovery to evaluate amyloid- lowering therapeutics.
    Hussain I
    CNS Neurol Disord Drug Targets; 2010 Aug; 9(4):395-402. PubMed ID: 20522015
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Donepezil attenuates Aβ-associated mitochondrial dysfunction and reduces mitochondrial Aβ accumulation in vivo and in vitro.
    Ye CY; Lei Y; Tang XC; Zhang HY
    Neuropharmacology; 2015 Aug; 95():29-36. PubMed ID: 25744714
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Effects of accelerated senescence on learning and memory, locomotion and anxiety-like behavior in APP/PS1 mouse model of Alzheimer's disease.
    Lok K; Zhao H; Zhang C; He N; Shen H; Wang Z; Zhao W; Yin M
    J Neurol Sci; 2013 Dec; 335(1-2):145-54. PubMed ID: 24095271
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's disease.
    Willuweit A; Velden J; Godemann R; Manook A; Jetzek F; Tintrup H; Kauselmann G; Zevnik B; Henriksen G; Drzezga A; Pohlner J; Schoor M; Kemp JA; von der Kammer H
    PLoS One; 2009 Nov; 4(11):e7931. PubMed ID: 19936202
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Neuroprotective role of trans-resveratrol in a murine model of familial Alzheimer's disease.
    Porquet D; Griñán-Ferré C; Ferrer I; Camins A; Sanfeliu C; Del Valle J; Pallàs M
    J Alzheimers Dis; 2014; 42(4):1209-20. PubMed ID: 25024312
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Protocatechuic acid improves cognitive deficits and attenuates amyloid deposits, inflammatory response in aged AβPP/PS1 double transgenic mice.
    Song Y; Cui T; Xie N; Zhang X; Qian Z; Liu J
    Int Immunopharmacol; 2014 May; 20(1):276-81. PubMed ID: 24667368
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
    Jaffar S; Counts SE; Ma SY; Dadko E; Gordon MN; Morgan D; Mufson EJ
    Exp Neurol; 2001 Aug; 170(2):227-43. PubMed ID: 11476589
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Pro-oxidant diet enhances β/γ secretase-mediated APP processing in APP/PS1 transgenic mice.
    Choudhry F; Howlett DR; Richardson JC; Francis PT; Williams RJ
    Neurobiol Aging; 2012 May; 33(5):960-8. PubMed ID: 20724034
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Icariin, a phosphodiesterase-5 inhibitor, improves learning and memory in APP/PS1 transgenic mice by stimulation of NO/cGMP signalling.
    Jin F; Gong QH; Xu YS; Wang LN; Jin H; Li F; Li LS; Ma YM; Shi JS
    Int J Neuropsychopharmacol; 2014 Jun; 17(6):871-81. PubMed ID: 24513083
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A transgenic rat model of Alzheimer's disease with extracellular Abeta deposition.
    Flood DG; Lin YG; Lang DM; Trusko SP; Hirsch JD; Savage MJ; Scott RW; Howland DS
    Neurobiol Aging; 2009 Jul; 30(7):1078-90. PubMed ID: 18053619
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Neuroprotective effect of emodin against Alzheimer's disease via Nrf2 signaling in U251 cells and APP/PS1 mice.
    Li Z; Bi H; Jiang H; Song J; Meng Q; Zhang Y; Fei X
    Mol Med Rep; 2021 Feb; 23(2):. PubMed ID: 33300068
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Stromal cell-derived factor 1α decreases β-amyloid deposition in Alzheimer's disease mouse model.
    Wang Q; Xu Y; Chen JC; Qin YY; Liu M; Liu Y; Xie MJ; Yu ZY; Zhu Z; Wang W
    Brain Res; 2012 Jun; 1459():15-26. PubMed ID: 22560596
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Tauroursodeoxycholic acid suppresses amyloid β-induced synaptic toxicity in vitro and in APP/PS1 mice.
    Ramalho RM; Nunes AF; Dias RB; Amaral JD; Lo AC; D'Hooge R; Sebastião AM; Rodrigues CM
    Neurobiol Aging; 2013 Feb; 34(2):551-61. PubMed ID: 22621777
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease.
    Pihlaja R; Koistinaho J; Malm T; Sikkilä H; Vainio S; Koistinaho M
    Glia; 2008 Jan; 56(2):154-63. PubMed ID: 18004725
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Increase in presenilin 1 (PS1) levels in senescence-accelerated mice (SAMP8) may indirectly impair memory by affecting amyloid precursor protein (APP) processing.
    Kumar VB; Franko M; Banks WA; Kasinadhuni P; Farr SA; Vyas K; Choudhuri V; Morley JE
    J Exp Biol; 2009 Feb; 212(Pt 4):494-8. PubMed ID: 19181896
    [TBL] [Abstract][Full Text] [Related]  

  • 36. [Effects of huannao yicong recipe extract on the learning and memory and related factors of Abeta generation in the brain of APP transgenic mice].
    Li H; Liu MF; Liu JG; Liu LT; Guan J; Cai LL; Hu J; Wei Y
    Zhongguo Zhong Xi Yi Jie He Za Zhi; 2013 Jan; 33(1):90-4. PubMed ID: 23596795
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A modified formulation of Chinese traditional medicine improves memory impairment and reduces Aβ level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer's disease.
    Jeon S; Bose S; Hur J; Jun K; Kim YK; Cho KS; Koo BS
    J Ethnopharmacol; 2011 Sep; 137(1):783-9. PubMed ID: 21762767
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Alternations of central insulin-like growth factor-1 sensitivity in APP/PS1 transgenic mice and neuronal models.
    Zhang B; Tang XC; Zhang HY
    J Neurosci Res; 2013 May; 91(5):717-25. PubMed ID: 23401344
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ
    Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice.
    Trinchese F; Liu S; Battaglia F; Walter S; Mathews PM; Arancio O
    Ann Neurol; 2004 Jun; 55(6):801-14. PubMed ID: 15174014
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.