BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 21972248)

  • 1. Rational design of novel anti-microtubule agent (9-azido-noscapine) from quantitative structure activity relationship (QSAR) evaluation of noscapinoids.
    Santoshi S; Naik PK; Joshi HC
    J Biomol Screen; 2011 Oct; 16(9):1047-58. PubMed ID: 21972248
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rational design of the microtubule-targeting anti-breast cancer drug EM015.
    Aneja R; Lopus M; Zhou J; Vangapandu SN; Ghaleb A; Yao J; Nettles JH; Zhou B; Gupta M; Panda D; Chandra R; Joshi HC
    Cancer Res; 2006 Apr; 66(7):3782-91. PubMed ID: 16585205
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Noscapinoids with anti-cancer activity against human acute lymphoblastic leukemia cells (CEM): a three dimensional chemical space pharmacophore modeling and electronic feature analysis.
    Naik PK; Santoshi S; Joshi HC
    J Mol Model; 2012 Jan; 18(1):307-18. PubMed ID: 21523542
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rational design of biaryl pharmacophore inserted noscapine derivatives as potent tubulin binding anticancer agents.
    Santoshi S; Manchukonda NK; Suri C; Sharma M; Sridhar B; Joseph S; Lopus M; Kantevari S; Baitharu I; Naik PK
    J Comput Aided Mol Des; 2015 Mar; 29(3):249-70. PubMed ID: 25481458
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rational design, synthesis and biological evaluations of amino-noscapine: a high affinity tubulin-binding noscapinoid.
    Naik PK; Chatterji BP; Vangapandu SN; Aneja R; Chandra R; Kanteveri S; Joshi HC
    J Comput Aided Mol Des; 2011 May; 25(5):443-54. PubMed ID: 21544622
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Determination of noscapine's localization and interaction with the tubulin-α/β heterodimer.
    Alisaraie L; Tuszynski JA
    Chem Biol Drug Des; 2011 Oct; 78(4):535-46. PubMed ID: 21781284
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rational design, synthesis, and biological evaluation of third generation α-noscapine analogues as potent tubulin binding anti-cancer agents.
    Manchukonda NK; Naik PK; Santoshi S; Lopus M; Joseph S; Sridhar B; Kantevari S
    PLoS One; 2013; 8(10):e77970. PubMed ID: 24205049
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular modeling and structure-activity relationship of podophyllotoxin and its congeners.
    Naik PK; Alam A; Malhotra A; Rizvi O
    J Biomol Screen; 2010 Jun; 15(5):528-40. PubMed ID: 20460251
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of S-phase arresting agents derived from noscapine.
    Anderson JT; Ting AE; Boozer S; Brunden KR; Danzig J; Dent T; Harrington JJ; Murphy SM; Perry R; Raber A; Rundlett SE; Wang J; Wang N; Bennani YL
    J Med Chem; 2005 Apr; 48(8):2756-8. PubMed ID: 15828811
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of microtubule-interfering halogenated noscapine analogs that perturb mitosis in cancer cells followed by cell death.
    Aneja R; Vangapandu SN; Lopus M; Viswesarappa VG; Dhiman N; Verma A; Chandra R; Panda D; Joshi HC
    Biochem Pharmacol; 2006 Aug; 72(4):415-26. PubMed ID: 16780803
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design and QSAR study of analogs of gamma-tocotrienol with enhanced antiproliferative activity against human breast cancer cells.
    Nikolic K; Agababa D
    J Mol Graph Model; 2009 Apr; 27(7):777-83. PubMed ID: 19117779
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Combined molecular dynamics and continuum solvent approaches (MM-PBSA/GBSA) to predict noscapinoid binding to γ-tubulin dimer.
    Suri C; Naik PK
    SAR QSAR Environ Res; 2015 Jun; 26(6):507-19. PubMed ID: 26274780
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Novel Class of N-Sulfonyl and N-Sulfamoyl Noscapine Derivatives that Promote Mitotic Arrest in Cancer Cells.
    Yong C; Devine SM; Gao X; Yan A; Callaghan R; Capuano B; Scammells PJ
    ChemMedChem; 2019 Dec; 14(23):1968-1981. PubMed ID: 31714012
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and biological evaluation of di-substituted noscapine analogs as potent and microtubule-targeted anticancer agents.
    Mishra RC; Gundala SR; Karna P; Lopus M; Gupta KK; Nagaraju M; Hamelberg D; Tandon V; Panda D; Reid MD; Aneja R
    Bioorg Med Chem Lett; 2015; 25(10):2133-40. PubMed ID: 25891106
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of novel and improved antimitotic agents derived from noscapine.
    Anderson JT; Ting AE; Boozer S; Brunden KR; Crumrine C; Danzig J; Dent T; Faga L; Harrington JJ; Hodnick WF; Murphy SM; Pawlowski G; Perry R; Raber A; Rundlett SE; Stricker-Krongrad A; Wang J; Bennani YL
    J Med Chem; 2005 Nov; 48(23):7096-8. PubMed ID: 16279766
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A new antiproliferative noscapine analogue: chemical synthesis and biological evaluation.
    Ghaly PE; Abou El-Magd RM; Churchill CD; Tuszynski JA; West FG
    Oncotarget; 2016 Jun; 7(26):40518-40530. PubMed ID: 27777381
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insights into the structure and tubulin-targeted anticancer potential of N-(3-bromobenzyl) noscapine.
    Cheriyamundath S; Mahaddalkar T; Reddy Nagireddy PK; Sridhar B; Kantevari S; Lopus M
    Pharmacol Rep; 2019 Feb; 71(1):48-53. PubMed ID: 30465924
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Comprehension into Target Binding and Spatial Fingerprints of Noscapinoid Analogues as Inhibitors of Tubulin.
    Mandavi S; Verma SK; Banjare L; Dubey A; Bhatt R; Thareja S; Jain AK
    Med Chem; 2021; 17(6):611-622. PubMed ID: 31951171
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tubulin binding, protein-bound conformation in solution, and antimitotic cellular profiling of noscapine and its derivatives.
    Bennani YL; Gu W; Canales A; Díaz FJ; Eustace BK; Hoover RR; Jiménez-Barbero J; Nezami A; Wang T
    J Med Chem; 2012 Mar; 55(5):1920-5. PubMed ID: 22320354
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rational design of novel N-alkyl amine analogues of noscapine, their chemical synthesis and cellular activity as potent anticancer agents.
    Meher RK; Pragyandipta P; Pedapati RK; Nagireddy PKR; Kantevari S; Nayek AK; Naik PK
    Chem Biol Drug Des; 2021 Sep; 98(3):445-465. PubMed ID: 34051055
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.