These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

418 related articles for article (PubMed ID: 21975039)

  • 1. Generation of reactive oxygen species in 1-methyl-4-phenylpyridinium (MPP+) treated dopaminergic neurons occurs as an NADPH oxidase-dependent two-wave cascade.
    Zawada WM; Banninger GP; Thornton J; Marriott B; Cantu D; Rachubinski AL; Das M; Griffin WS; Jones SM
    J Neuroinflammation; 2011 Oct; 8():129. PubMed ID: 21975039
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cells.
    Anantharam V; Kaul S; Song C; Kanthasamy A; Kanthasamy AG
    Neurotoxicology; 2007 Sep; 28(5):988-97. PubMed ID: 17904225
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ultrafine carbon particles promote rotenone-induced dopamine neuronal loss through activating microglial NADPH oxidase.
    Wang Y; Liu D; Zhang H; Wang Y; Wei L; Liu Y; Liao J; Gao HM; Zhou H
    Toxicol Appl Pharmacol; 2017 May; 322():51-59. PubMed ID: 28283350
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of neuronal NADPH oxidase NOX2 promotes inflammatory neurodegeneration.
    Tu D; Velagapudi R; Gao Y; Hong JS; Zhou H; Gao HM
    Free Radic Biol Med; 2023 May; 200():47-58. PubMed ID: 36870375
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Downregulation of miR-124 in MPTP-treated mouse model of Parkinson's disease and MPP iodide-treated MN9D cells modulates the expression of the calpain/cdk5 pathway proteins.
    Kanagaraj N; Beiping H; Dheen ST; Tay SS
    Neuroscience; 2014 Jul; 272():167-79. PubMed ID: 24792712
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase.
    Jiang L; Wu X; Wang S; Chen SH; Zhou H; Wilson B; Jin CY; Lu RB; Xie K; Wang Q; Hong JS
    J Neuroinflammation; 2016 May; 13(1):110. PubMed ID: 27184631
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia.
    Qin L; Liu Y; Wang T; Wei SJ; Block ML; Wilson B; Liu B; Hong JS
    J Biol Chem; 2004 Jan; 279(2):1415-21. PubMed ID: 14578353
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase.
    Wang Q; Chu CH; Qian L; Chen SH; Wilson B; Oyarzabal E; Jiang L; Ali S; Robinson B; Kim HC; Hong JS
    J Neurosci; 2014 Sep; 34(37):12490-503. PubMed ID: 25209287
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease.
    Ghosh A; Saminathan H; Kanthasamy A; Anantharam V; Jin H; Sondarva G; Harischandra DS; Qian Z; Rana A; Kanthasamy AG
    J Biol Chem; 2013 Jul; 288(30):21955-71. PubMed ID: 23754278
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TRPM2 Promotes Neurotoxin MPP
    Sun Y; Sukumaran P; Selvaraj S; Cilz NI; Schaar A; Lei S; Singh BB
    Mol Neurobiol; 2018 Jan; 55(1):409-420. PubMed ID: 27957685
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytotoxicity of paraquat in microglial cells: Involvement of PKCdelta- and ERK1/2-dependent NADPH oxidase.
    Miller RL; Sun GY; Sun AY
    Brain Res; 2007 Sep; 1167():129-39. PubMed ID: 17662968
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role and mechanism of microglial activation in iron-induced selective and progressive dopaminergic neurodegeneration.
    Zhang W; Yan ZF; Gao JH; Sun L; Huang XY; Liu Z; Yu SY; Cao CJ; Zuo LJ; Chen ZJ; Hu Y; Wang F; Hong JS; Wang XM
    Mol Neurobiol; 2014 Jun; 49(3):1153-65. PubMed ID: 24277523
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NADPH ameliorates MPTP-induced dopaminergic neurodegeneration through inhibiting p38MAPK activation.
    Zhou JS; Zhu Z; Wu F; Zhou Y; Sheng R; Wu JC; Qin ZH
    Acta Pharmacol Sin; 2019 Feb; 40(2):180-191. PubMed ID: 29769744
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity.
    Zhang D; Hu X; Wei SJ; Liu J; Gao H; Qian L; Wilson B; Liu G; Hong JS
    J Neuroinflammation; 2008 May; 5():21. PubMed ID: 18507839
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fluoxetine prevents MPTP-induced loss of dopaminergic neurons by inhibiting microglial activation.
    Chung YC; Kim SR; Park JY; Chung ES; Park KW; Won SY; Bok E; Jin M; Park ES; Yoon SH; Ko HW; Kim YS; Jin BK
    Neuropharmacology; 2011 May; 60(6):963-74. PubMed ID: 21288472
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Secalonic acid A protects dopaminergic neurons from 1-methyl-4-phenylpyridinium (MPP⁺)-induced cell death via the mitochondrial apoptotic pathway.
    Zhai A; Zhu X; Wang X; Chen R; Wang H
    Eur J Pharmacol; 2013 Aug; 713(1-3):58-67. PubMed ID: 23665112
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Therapeutic effects of multifunctional tetramethylpyrazine nitrone on models of Parkinson's disease in vitro and in vivo.
    Guo B; Xu D; Duan H; Du J; Zhang Z; Lee SM; Wang Y
    Biol Pharm Bull; 2014; 37(2):274-85. PubMed ID: 24305623
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
    Wu DC; Teismann P; Tieu K; Vila M; Jackson-Lewis V; Ischiropoulos H; Przedborski S
    Proc Natl Acad Sci U S A; 2003 May; 100(10):6145-50. PubMed ID: 12721370
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Matrix metalloproteinase-3 causes dopaminergic neuronal death through Nox1-regenerated oxidative stress.
    Choi DH; Kim JH; Seo JH; Lee J; Choi WS; Kim YS
    PLoS One; 2014; 9(12):e115954. PubMed ID: 25536219
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration.
    Tu D; Gao Y; Yang R; Guan T; Hong JS; Gao HM
    J Neuroinflammation; 2019 Dec; 16(1):255. PubMed ID: 31805953
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.