243 related articles for article (PubMed ID: 21975728)
1. Inhibition of nicotinamide phosphoribosyltransferase modifies LPS-induced inflammatory responses of human monocytes.
Schilling E; Wehrhahn J; Klein C; Raulien N; Ceglarek U; Hauschildt S
Innate Immun; 2012 Jun; 18(3):518-30. PubMed ID: 21975728
[TBL] [Abstract][Full Text] [Related]
2. Anti-proliferation effect of APO866 on C6 glioblastoma cells by inhibiting nicotinamide phosphoribosyltransferase.
Zhang LY; Liu LY; Qie LL; Ling KN; Xu LH; Wang F; Fang SH; Lu YB; Hu H; Wei EQ; Zhang WP
Eur J Pharmacol; 2012 Jan; 674(2-3):163-70. PubMed ID: 22119381
[TBL] [Abstract][Full Text] [Related]
3. Distinct effects of Nampt inhibition on mild and severe models of lipopolysaccharide-induced myocardial impairment.
Liu L; Wang P; Liang C; He D; Yu Y; Liu X
Int Immunopharmacol; 2013 Oct; 17(2):342-9. PubMed ID: 23831038
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of pre-B cell colony-enhancing factor (PBEF/NAMPT/visfatin) decreases the ability of human neutrophils to generate reactive oxidants but does not impair bacterial killing.
Roberts KJ; Cross A; Vasieva O; Moots RJ; Edwards SW
J Leukoc Biol; 2013 Sep; 94(3):481-92. PubMed ID: 23804809
[TBL] [Abstract][Full Text] [Related]
5. Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells.
Zoppoli G; Cea M; Soncini D; Fruscione F; Rudner J; Moran E; Caffa I; Bedognetti D; Motta G; Ghio R; Ferrando F; Ballestrero A; Parodi S; Belka C; Patrone F; Bruzzone S; Nencioni A
Exp Hematol; 2010 Nov; 38(11):979-88. PubMed ID: 20696207
[TBL] [Abstract][Full Text] [Related]
6. CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells.
Grozio A; Sociali G; Sturla L; Caffa I; Soncini D; Salis A; Raffaelli N; De Flora A; Nencioni A; Bruzzone S
J Biol Chem; 2013 Sep; 288(36):25938-25949. PubMed ID: 23880765
[TBL] [Abstract][Full Text] [Related]
7. NAMPT inhibitor and metabolite protect mouse brain from cryoinjury through distinct mechanisms.
Zhang XQ; Lu JT; Jiang WX; Lu YB; Wu M; Wei EQ; Zhang WP; Tang C
Neuroscience; 2015 Apr; 291():230-40. PubMed ID: 25684751
[TBL] [Abstract][Full Text] [Related]
8. Nicotinamide phosphoribosyltransferase (NAMPT) activity is essential for survival of resting lymphocytes.
Pittelli M; Cavone L; Lapucci A; Oteri C; Felici R; Niccolai E; Amedei A; Chiarugi A
Immunol Cell Biol; 2014 Feb; 92(2):191-9. PubMed ID: 24275857
[TBL] [Abstract][Full Text] [Related]
9. Overexpression of Nampt in gastric cancer and chemopotentiating effects of the Nampt inhibitor FK866 in combination with fluorouracil.
Bi TQ; Che XM; Liao XH; Zhang DJ; Long HL; Li HJ; Zhao W
Oncol Rep; 2011 Nov; 26(5):1251-7. PubMed ID: 21743967
[TBL] [Abstract][Full Text] [Related]
10. NAD metabolism fuels human and mouse intestinal inflammation.
Gerner RR; Klepsch V; Macheiner S; Arnhard K; Adolph TE; Grander C; Wieser V; Pfister A; Moser P; Hermann-Kleiter N; Baier G; Oberacher H; Tilg H; Moschen AR
Gut; 2018 Oct; 67(10):1813-1823. PubMed ID: 28877980
[TBL] [Abstract][Full Text] [Related]
11. Novel Mechanism for Nicotinamide Phosphoribosyltransferase Inhibition of TNF-α-mediated Apoptosis in Human Lung Endothelial Cells.
Oita RC; Camp SM; Ma W; Ceco E; Harbeck M; Singleton P; Messana J; Sun X; Wang T; Garcia JGN
Am J Respir Cell Mol Biol; 2018 Jul; 59(1):36-44. PubMed ID: 29337590
[TBL] [Abstract][Full Text] [Related]
12. Oleate ameliorates palmitate-induced reduction of NAMPT activity and NAD levels in primary human hepatocytes and hepatocarcinoma cells.
Penke M; Schuster S; Gorski T; Gebhardt R; Kiess W; Garten A
Lipids Health Dis; 2017 Oct; 16(1):191. PubMed ID: 28974242
[TBL] [Abstract][Full Text] [Related]
13. Extracellular ATP induces P2X7-dependent nicotinamide phosphoribosyltransferase release in LPS-activated human monocytes.
Schilling E; Hauschildt S
Innate Immun; 2012 Oct; 18(5):738-44. PubMed ID: 22377803
[TBL] [Abstract][Full Text] [Related]
14. The nicotinamide phosphoribosyltransferase: a molecular link between metabolism, inflammation, and cancer.
Gallí M; Van Gool F; Rongvaux A; Andris F; Leo O
Cancer Res; 2010 Jan; 70(1):8-11. PubMed ID: 20028851
[TBL] [Abstract][Full Text] [Related]
15. APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells.
Cagnetta A; Caffa I; Acharya C; Soncini D; Acharya P; Adamia S; Pierri I; Bergamaschi M; Garuti A; Fraternali G; Mastracci L; Provenzani A; Zucal C; Damonte G; Salis A; Montecucco F; Patrone F; Ballestrero A; Bruzzone S; Gobbi M; Nencioni A; Cea M
Clin Cancer Res; 2015 Sep; 21(17):3934-45. PubMed ID: 25964294
[TBL] [Abstract][Full Text] [Related]
16. Nicotinamide phosphoribosyltransferase inhibitor APO866 induces C6 glioblastoma cell death via autophagy.
Yang P; Zhang L; Shi QJ; Lu YB; Wu M; Wei EQ; Zhang WP
Pharmazie; 2015 Oct; 70(10):650-5. PubMed ID: 26601421
[TBL] [Abstract][Full Text] [Related]
17. FK866-induced NAMPT inhibition activates AMPK and downregulates mTOR signaling in hepatocarcinoma cells.
Schuster S; Penke M; Gorski T; Gebhardt R; Weiss TS; Kiess W; Garten A
Biochem Biophys Res Commun; 2015 Mar; 458(2):334-40. PubMed ID: 25656579
[TBL] [Abstract][Full Text] [Related]
18. NAMPT pathway is involved in the FOXO3a-mediated regulation of GADD45A expression.
Thakur BK; Lippka Y; Dittrich T; Chandra P; Skokowa J; Welte K
Biochem Biophys Res Commun; 2012 Apr; 420(4):714-20. PubMed ID: 22430142
[TBL] [Abstract][Full Text] [Related]
19. Restoring NAD
Katayoshi T; Nakajo T; Tsuji-Naito K
J Photochem Photobiol B; 2021 Aug; 221():112238. PubMed ID: 34130091
[TBL] [Abstract][Full Text] [Related]
20. Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells.
Yang NC; Song TY; Chang YZ; Chen MY; Hu ML
Biogerontology; 2015 Feb; 16(1):31-42. PubMed ID: 25146190
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]