These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

474 related articles for article (PubMed ID: 21975933)

  • 1. Novel histone demethylase LSD1 inhibitors selectively target cancer cells with pluripotent stem cell properties.
    Wang J; Lu F; Ren Q; Sun H; Xu Z; Lan R; Liu Y; Ward D; Quan J; Ye T; Zhang H
    Cancer Res; 2011 Dec; 71(23):7238-49. PubMed ID: 21975933
    [TBL] [Abstract][Full Text] [Related]  

  • 2. New histone demethylase LSD1 inhibitor selectively targets teratocarcinoma and embryonic carcinoma cells.
    Hoang N; Zhang X; Zhang C; Vo V; Leng F; Saxena L; Yin F; Lu F; Zheng G; Bhowmik P; Zhang H
    Bioorg Med Chem; 2018 May; 26(8):1523-1537. PubMed ID: 29439916
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LSD1 regulates pluripotency of embryonic stem/carcinoma cells through histone deacetylase 1-mediated deacetylation of histone H4 at lysine 16.
    Yin F; Lan R; Zhang X; Zhu L; Chen F; Xu Z; Liu Y; Ye T; Sun H; Lu F; Zhang H
    Mol Cell Biol; 2014 Jan; 34(2):158-79. PubMed ID: 24190971
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pluripotent stem cell protein Sox2 confers sensitivity to LSD1 inhibition in cancer cells.
    Zhang X; Lu F; Wang J; Yin F; Xu Z; Qi D; Wu X; Cao Y; Liang W; Liu Y; Sun H; Ye T; Zhang H
    Cell Rep; 2013 Oct; 5(2):445-57. PubMed ID: 24139802
    [TBL] [Abstract][Full Text] [Related]  

  • 5. LSD1 demethylase and the methyl-binding protein PHF20L1 prevent SET7 methyltransferase-dependent proteolysis of the stem-cell protein SOX2.
    Zhang C; Hoang N; Leng F; Saxena L; Lee L; Alejo S; Qi D; Khal A; Sun H; Lu F; Zhang H
    J Biol Chem; 2018 Mar; 293(10):3663-3674. PubMed ID: 29358331
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch.
    Sun H; Liang L; Li Y; Feng C; Li L; Zhang Y; He S; Pei D; Guo Y; Zheng H
    Sci Rep; 2016 Aug; 6():30903. PubMed ID: 27481483
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4.
    Metzger E; Imhof A; Patel D; Kahl P; Hoffmeyer K; Friedrichs N; Müller JM; Greschik H; Kirfel J; Ji S; Kunowska N; Beisenherz-Huss C; Günther T; Buettner R; Schüle R
    Nature; 2010 Apr; 464(7289):792-6. PubMed ID: 20228790
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The malignant brain tumor (MBT) domain protein SFMBT1 is an integral histone reader subunit of the LSD1 demethylase complex for chromatin association and epithelial-to-mesenchymal transition.
    Tang M; Shen H; Jin Y; Lin T; Cai Q; Pinard MA; Biswas S; Tran Q; Li G; Shenoy AK; Tongdee E; Lin S; Gu Y; Law BK; Zhou L; Mckenna R; Wu L; Lu J
    J Biol Chem; 2013 Sep; 288(38):27680-27691. PubMed ID: 23928305
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Systematic Review of Histone Lysine-Specific Demethylase 1 and Its Inhibitors.
    Zheng YC; Ma J; Wang Z; Li J; Jiang B; Zhou W; Shi X; Wang X; Zhao W; Liu HM
    Med Res Rev; 2015 Sep; 35(5):1032-71. PubMed ID: 25990136
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lysine-specific histone demethylase 1 (LSD1): A potential molecular target for tumor therapy.
    Chen Y; Jie W; Yan W; Zhou K; Xiao Y
    Crit Rev Eukaryot Gene Expr; 2012; 22(1):53-9. PubMed ID: 22339659
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Silencing of LSD1 gene modulates histone methylation and acetylation and induces the apoptosis of JeKo-1 and MOLT-4 cells.
    Zou ZK; Huang YQ; Zou Y; Zheng XK; Ma XD
    Int J Mol Med; 2017 Aug; 40(2):319-328. PubMed ID: 28627608
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells.
    Adamo A; Sesé B; Boue S; Castaño J; Paramonov I; Barrero MJ; Izpisua Belmonte JC
    Nat Cell Biol; 2011 Jun; 13(6):652-9. PubMed ID: 21602794
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes.
    El Mansouri FE; Nebbaki SS; Kapoor M; Afif H; Martel-Pelletier J; Pelletier JP; Benderdour M; Fahmi H
    Arthritis Res Ther; 2014 May; 16(3):R113. PubMed ID: 24886859
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 3-(Piperidin-4-ylmethoxy)pyridine Containing Compounds Are Potent Inhibitors of Lysine Specific Demethylase 1.
    Wu F; Zhou C; Yao Y; Wei L; Feng Z; Deng L; Song Y
    J Med Chem; 2016 Jan; 59(1):253-263. PubMed ID: 26652247
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia.
    Feng Z; Yao Y; Zhou C; Chen F; Wu F; Wei L; Liu W; Dong S; Redell M; Mo Q; Song Y
    J Hematol Oncol; 2016 Mar; 9():24. PubMed ID: 26970896
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The re-expression of the epigenetically silenced e-cadherin gene by a polyamine analogue lysine-specific demethylase-1 (LSD1) inhibitor in human acute myeloid leukemia cell lines.
    Murray-Stewart T; Woster PM; Casero RA
    Amino Acids; 2014 Mar; 46(3):585-94. PubMed ID: 23508577
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1/KDM1A.
    Cuyàs E; Gumuzio J; Lozano-Sánchez J; Carreras D; Verdura S; Llorach-Parés L; Sanchez-Martinez M; Selga E; Pérez GJ; Scornik FS; Brugada R; Bosch-Barrera J; Segura-Carretero A; Martin ÁG; Encinar JA; Menendez JA
    Nutrients; 2019 Jul; 11(7):. PubMed ID: 31331073
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression.
    Lan F; Collins RE; De Cegli R; Alpatov R; Horton JR; Shi X; Gozani O; Cheng X; Shi Y
    Nature; 2007 Aug; 448(7154):718-22. PubMed ID: 17687328
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ZY0511, a novel, potent and selective LSD1 inhibitor, exhibits anticancer activity against solid tumors via the DDIT4/mTOR pathway.
    Li Y; Tao L; Zuo Z; Zhou Y; Qian X; Lin Y; Jie H; Liu C; Li Z; Zhang H; Zhang H; Cen X; Yang S; Zhao Y
    Cancer Lett; 2019 Jul; 454():179-190. PubMed ID: 30978443
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology.
    Lim S; Janzer A; Becker A; Zimmer A; Schüle R; Buettner R; Kirfel J
    Carcinogenesis; 2010 Mar; 31(3):512-20. PubMed ID: 20042638
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.