195 related articles for article (PubMed ID: 21976708)
1. Ectodomain shedding of HB-EGF: a potential target for cancer therapy.
Miyazono K
J Biochem; 2012 Jan; 151(1):1-3. PubMed ID: 21976708
[TBL] [Abstract][Full Text] [Related]
2. Anti-human HB-EGF monoclonal antibodies inhibiting ectodomain shedding of HB-EGF and diphtheria toxin binding.
Hamaoka M; Chinen I; Murata T; Takashima S; Iwamoto R; Mekada E
J Biochem; 2010 Jul; 148(1):55-69. PubMed ID: 20332144
[TBL] [Abstract][Full Text] [Related]
3. Spatiotemporal visualization of proHB-EGF ectodomain shedding in living cells.
Inoue H; Sakaue T; Ozawa T; Higashiyama S
J Biochem; 2013 Jul; 154(1):67-76. PubMed ID: 23598347
[TBL] [Abstract][Full Text] [Related]
4. Ectodomain shedding of membrane-anchored heparin-binding EGF like growth factor and subcellular localization of the C-terminal fragment in the cell cycle.
Toki F; Nanba D; Matsuura N; Higashiyama S
J Cell Physiol; 2005 Mar; 202(3):839-48. PubMed ID: 15389565
[TBL] [Abstract][Full Text] [Related]
5. Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity.
Goishi K; Higashiyama S; Klagsbrun M; Nakano N; Umata T; Ishikawa M; Mekada E; Taniguchi N
Mol Biol Cell; 1995 Aug; 6(8):967-80. PubMed ID: 7579712
[TBL] [Abstract][Full Text] [Related]
6. Insufficiency of pro-heparin-binding epidermal growth factor-like growth factor shedding enhances hypoxic cell death in H9c2 cardiomyoblasts via the activation of caspase-3 and c-Jun N-terminal kinase.
Uetani T; Nakayama H; Okayama H; Okura T; Higaki J; Inoue H; Higashiyama S
J Biol Chem; 2009 May; 284(18):12399-409. PubMed ID: 19193634
[TBL] [Abstract][Full Text] [Related]
7. Importance of the major extracellular domain of CD9 and the epidermal growth factor (EGF)-like domain of heparin-binding EGF-like growth factor for up-regulation of binding and activity.
Nakamura K; Mitamura T; Takahashi T; Kobayashi T; Mekada E
J Biol Chem; 2000 Jun; 275(24):18284-90. PubMed ID: 10749879
[TBL] [Abstract][Full Text] [Related]
8. Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy.
Miyamoto S; Hirata M; Yamazaki A; Kageyama T; Hasuwa H; Mizushima H; Tanaka Y; Yagi H; Sonoda K; Kai M; Kanoh H; Nakano H; Mekada E
Cancer Res; 2004 Aug; 64(16):5720-7. PubMed ID: 15313912
[TBL] [Abstract][Full Text] [Related]
9. TGFβ induces proHB-EGF shedding and EGFR transactivation through ADAM activation in gastric cancer cells.
Ebi M; Kataoka H; Shimura T; Kubota E; Hirata Y; Mizushima T; Mizoshita T; Tanaka M; Mabuchi M; Tsukamoto H; Tanida S; Kamiya T; Higashiyama S; Joh T
Biochem Biophys Res Commun; 2010 Nov; 402(3):449-54. PubMed ID: 20934403
[TBL] [Abstract][Full Text] [Related]
10. The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor.
Higashiyama S; Iwamoto R; Goishi K; Raab G; Taniguchi N; Klagsbrun M; Mekada E
J Cell Biol; 1995 Mar; 128(5):929-38. PubMed ID: 7876316
[TBL] [Abstract][Full Text] [Related]
11. Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites.
Nakamura K; Iwamoto R; Mekada E
J Cell Biol; 1995 Jun; 129(6):1691-705. PubMed ID: 7790364
[TBL] [Abstract][Full Text] [Related]
12. Heparin-binding EGF-like growth factor: a juxtacrine growth factor.
Iwamoto R; Mekada E
Cytokine Growth Factor Rev; 2000 Dec; 11(4):335-44. PubMed ID: 10959080
[TBL] [Abstract][Full Text] [Related]
13. Heparin-like molecules on the cell surface potentiate binding of diphtheria toxin to the diphtheria toxin receptor/membrane-anchored heparin-binding epidermal growth factor-like growth factor.
Shishido Y; Sharma KD; Higashiyama S; Klagsbrun M; Mekada E
J Biol Chem; 1995 Dec; 270(49):29578-85. PubMed ID: 7494001
[TBL] [Abstract][Full Text] [Related]
14. Insulin-induced ectodomain shedding of heparin-binding epidermal growth factor-like growth factor in adipocytes in vitro.
Yamamoto T; Suganami T; Kiso-Narita M; Scherle PA; Kamei Y; Isobe M; Higashiyama S; Ogawa Y
Obesity (Silver Spring); 2010 Oct; 18(10):1888-94. PubMed ID: 20111015
[TBL] [Abstract][Full Text] [Related]
15. Diphtheria toxin mutant CRM197 possesses weak EF2-ADP-ribosyl activity that potentiates its anti-tumorigenic activity.
Kageyama T; Ohishi M; Miyamoto S; Mizushima H; Iwamoto R; Mekada E
J Biochem; 2007 Jul; 142(1):95-104. PubMed ID: 17525101
[TBL] [Abstract][Full Text] [Related]
16. Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities.
Yamazaki S; Iwamoto R; Saeki K; Asakura M; Takashima S; Yamazaki A; Kimura R; Mizushima H; Moribe H; Higashiyama S; Endoh M; Kaneda Y; Takagi S; Itami S; Takeda N; Yamada G; Mekada E
J Cell Biol; 2003 Nov; 163(3):469-75. PubMed ID: 14597776
[TBL] [Abstract][Full Text] [Related]
17. Transactivation of epidermal growth factor receptor after heparin-binding epidermal growth factor-like growth factor shedding in the migration of prostate cancer cells promoted by bombesin.
Madarame J; Higashiyama S; Kiyota H; Madachi A; Toki F; Shimomura T; Tani N; Oishi Y; Matsuura N
Prostate; 2003 Nov; 57(3):187-95. PubMed ID: 14518027
[TBL] [Abstract][Full Text] [Related]
18. Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity.
Mitamura T; Higashiyama S; Taniguchi N; Klagsbrun M; Mekada E
J Biol Chem; 1995 Jan; 270(3):1015-9. PubMed ID: 7836353
[TBL] [Abstract][Full Text] [Related]
19. Identification of the cancer cell proliferation and survival functions of proHB-EGF by using an anti-HB-EGF antibody.
Sato S; Kamada H; Watanabe T; Tsuji I; Fan J
PLoS One; 2013; 8(1):e54509. PubMed ID: 23349913
[TBL] [Abstract][Full Text] [Related]
20. Induction of collecting duct morphogenesis in vitro by heparin-binding epidermal growth factor-like growth factor.
Takemura T; Hino S; Kuwajima H; Yanagida H; Okada M; Nagata M; Sasaki S; Barasch J; Harris RC; Yoshioka K
J Am Soc Nephrol; 2001 May; 12(5):964-972. PubMed ID: 11316855
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
