380 related articles for article (PubMed ID: 21978643)
1. Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.
Perego P; Cossa G; Tinelli S; Corna E; Carenini N; Gatti L; De Cesare M; Ciusani E; Zunino F; Luison E; Canevari S; Zaffaroni N; Beretta GL
Biochem Pharmacol; 2012 Jan; 83(1):27-36. PubMed ID: 21978643
[TBL] [Abstract][Full Text] [Related]
2. TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.
Zeng Z; Sharma A; Ju L; Murai J; Umans L; Vermeire L; Pommier Y; Takeda S; Huylebroeck D; Caldecott KW; El-Khamisy SF
Nucleic Acids Res; 2012 Sep; 40(17):8371-80. PubMed ID: 22740648
[TBL] [Abstract][Full Text] [Related]
3. TDP1 overexpression in human cells counteracts DNA damage mediated by topoisomerases I and II.
Barthelmes HU; Habermeyer M; Christensen MO; Mielke C; Interthal H; Pouliot JJ; Boege F; Marko D
J Biol Chem; 2004 Dec; 279(53):55618-25. PubMed ID: 15494395
[TBL] [Abstract][Full Text] [Related]
4. Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1.
Liu C; Pouliot JJ; Nash HA
Proc Natl Acad Sci U S A; 2002 Nov; 99(23):14970-5. PubMed ID: 12397185
[TBL] [Abstract][Full Text] [Related]
5. The role of TDP1 from budding yeast in the repair of DNA damage.
Liu C; Pouliot JJ; Nash HA
DNA Repair (Amst); 2004 Jun; 3(6):593-601. PubMed ID: 15135727
[TBL] [Abstract][Full Text] [Related]
6. Topoisomerase I activity and sensitivity to camptothecin in breast cancer-derived cells: a comparative study.
Tesauro C; Simonsen AK; Andersen MB; Petersen KW; Kristoffersen EL; Algreen L; Hansen NY; Andersen AB; Jakobsen AK; Stougaard M; Gromov P; Knudsen BR; Gromova I
BMC Cancer; 2019 Nov; 19(1):1158. PubMed ID: 31783818
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of Methoxy-, Methylenedioxy-, Hydroxy-, and Halo-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors and Their Biological Activity for Drug-Resistant Cancer.
Hu DX; Tang WL; Zhang Y; Yang H; Wang W; Agama K; Pommier Y; An LK
J Med Chem; 2021 Jun; 64(11):7617-7629. PubMed ID: 34008967
[TBL] [Abstract][Full Text] [Related]
8. Differential cytotoxic pathways of topoisomerase I and II anticancer agents after overexpression of the E2F-1/DP-1 transcription factor complex.
Hofland K; Petersen BO; Falck J; Helin K; Jensen PB; Sehested M
Clin Cancer Res; 2000 Apr; 6(4):1488-97. PubMed ID: 10778981
[TBL] [Abstract][Full Text] [Related]
9. DNA repair enzyme, O6-methylguanine DNA methyltransferase, modulates cytotoxicity of camptothecin-derived topoisomerase I inhibitors.
Kuo CC; Liu JF; Chang JY
J Pharmacol Exp Ther; 2006 Feb; 316(2):946-54. PubMed ID: 16258022
[TBL] [Abstract][Full Text] [Related]
10. Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions.
Plo I; Liao ZY; Barceló JM; Kohlhagen G; Caldecott KW; Weinfeld M; Pommier Y
DNA Repair (Amst); 2003 Oct; 2(10):1087-100. PubMed ID: 13679147
[TBL] [Abstract][Full Text] [Related]
11. Novel mutation of topoisomerase I in rendering cells resistant to camptothecin.
Chang JY; Liu JF; Juang SH; Liu TW; Chen LT
Cancer Res; 2002 Jul; 62(13):3716-21. PubMed ID: 12097280
[TBL] [Abstract][Full Text] [Related]
12. Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage.
Nitiss KC; Malik M; He X; White SW; Nitiss JL
Proc Natl Acad Sci U S A; 2006 Jun; 103(24):8953-8. PubMed ID: 16751265
[TBL] [Abstract][Full Text] [Related]
13. Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin.
El-Khamisy SF; Katyal S; Patel P; Ju L; McKinnon PJ; Caldecott KW
DNA Repair (Amst); 2009 Jun; 8(6):760-6. PubMed ID: 19303373
[TBL] [Abstract][Full Text] [Related]
14. Tyrosyl-DNA phosphodiesterase (Tdp1) (3'-phosphotyrosyl DNA phosphodiesterase).
Raymond AC; Burgin AB
Methods Enzymol; 2006; 409():511-24. PubMed ID: 16793421
[TBL] [Abstract][Full Text] [Related]
15. Differential GADD45, p21CIP1/WAF1, MCL-1 and topoisomerase II gene induction and secondary DNA fragmentation after camptothecin-induced DNA damage in two mutant p53 human colon cancer cell lines.
Goldwasser F; Bae I; Fornace AJ; Pommier Y
Oncol Res; 1996; 8(7-8):317-23. PubMed ID: 8938795
[TBL] [Abstract][Full Text] [Related]
16. Engineered resistance to camptothecin and antifolates by retroviral coexpression of tyrosyl DNA phosphodiesterase-I and thymidylate synthase.
Nivens MC; Felder T; Galloway AH; Pena MM; Pouliot JJ; Spencer HT
Cancer Chemother Pharmacol; 2004 Feb; 53(2):107-15. PubMed ID: 14605862
[TBL] [Abstract][Full Text] [Related]
17. Tdp1 processes chromate-induced single-strand DNA breaks that collapse replication forks.
Ganguly A; Guo L; Sun L; Suo F; Du LL; Russell P
PLoS Genet; 2018 Aug; 14(8):e1007595. PubMed ID: 30148840
[TBL] [Abstract][Full Text] [Related]
18. Tyrosyl-DNA phosphodiesterase 2 (TDP2) repairs topoisomerase 1 DNA-protein crosslinks and 3'-blocking lesions in the absence of tyrosyl-DNA phosphodiesterase 1 (TDP1).
Tsuda M; Kitamasu K; Kumagai C; Sugiyama K; Nakano T; Ide H
DNA Repair (Amst); 2020; 91-92():102849. PubMed ID: 32460231
[TBL] [Abstract][Full Text] [Related]
19. Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment.
Beretta GL; Cossa G; Gatti L; Zunino F; Perego P
Curr Med Chem; 2010; 17(15):1500-8. PubMed ID: 20166932
[TBL] [Abstract][Full Text] [Related]
20. Correlation between topoisomerase I and tyrosyl-DNA phosphodiesterase 1 activities in non-small cell lung cancer tissue.
Jakobsen AK; Lauridsen KL; Samuel EB; Proszek J; Knudsen BR; Hager H; Stougaard M
Exp Mol Pathol; 2015 Aug; 99(1):56-64. PubMed ID: 25987486
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]