179 related articles for article (PubMed ID: 21979880)
1. Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1.
Chaib H; Nebbioso A; Prebet T; Castellano R; Garbit S; Restouin A; Vey N; Altucci L; Collette Y
Leukemia; 2012 Apr; 26(4):662-74. PubMed ID: 21979880
[TBL] [Abstract][Full Text] [Related]
2. The SUV39H1 inhibitor chaetocin induces differentiation and shows synergistic cytotoxicity with other epigenetic drugs in acute myeloid leukemia cells.
Lai YS; Chen JY; Tsai HJ; Chen TY; Hung WC
Blood Cancer J; 2015 May; 5(5):e313. PubMed ID: 25978433
[TBL] [Abstract][Full Text] [Related]
3. Chaetocin induces endoplasmic reticulum stress response and leads to death receptor 5-dependent apoptosis in human non-small cell lung cancer cells.
Liu X; Guo S; Liu X; Su L
Apoptosis; 2015 Nov; 20(11):1499-507. PubMed ID: 26349783
[TBL] [Abstract][Full Text] [Related]
4. OSU-A9, an indole-3-carbinol derivative, induces cytotoxicity in acute myeloid leukemia through reactive oxygen species-mediated apoptosis.
Bai LY; Weng JR; Chiu CF; Wu CY; Yeh SP; Sargeant AM; Lin PH; Liao YM
Biochem Pharmacol; 2013 Nov; 86(10):1430-40. PubMed ID: 24041743
[TBL] [Abstract][Full Text] [Related]
5. Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.
Lakshmikuttyamma A; Scott SA; DeCoteau JF; Geyer CR
Oncogene; 2010 Jan; 29(4):576-88. PubMed ID: 19881540
[TBL] [Abstract][Full Text] [Related]
6. The Suv39H1 methyltransferase inhibitor chaetocin causes induction of integrated HIV-1 without producing a T cell response.
Bernhard W; Barreto K; Saunders A; Dahabieh MS; Johnson P; Sadowski I
FEBS Lett; 2011 Nov; 585(22):3549-54. PubMed ID: 22020221
[TBL] [Abstract][Full Text] [Related]
7. Improved therapeutic effect against leukemia by a combination of the histone methyltransferase inhibitor chaetocin and the histone deacetylase inhibitor trichostatin A.
Tran HT; Kim HN; Lee IK; Nguyen-Pham TN; Ahn JS; Kim YK; Lee JJ; Park KS; Kook H; Kim HJ
J Korean Med Sci; 2013 Feb; 28(2):237-46. PubMed ID: 23400519
[TBL] [Abstract][Full Text] [Related]
8. The histone deacetylase inhibitor ITF2357 has anti-leukemic activity in vitro and in vivo and inhibits IL-6 and VEGF production by stromal cells.
Golay J; Cuppini L; Leoni F; Micò C; Barbui V; Domenghini M; Lombardi L; Neri A; Barbui AM; Salvi A; Pozzi P; Porro G; Pagani P; Fossati G; Mascagni P; Introna M; Rambaldi A
Leukemia; 2007 Sep; 21(9):1892-900. PubMed ID: 17637810
[TBL] [Abstract][Full Text] [Related]
9. A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a.
Spensberger D; Delwel R
FEBS Lett; 2008 Aug; 582(18):2761-7. PubMed ID: 18619962
[TBL] [Abstract][Full Text] [Related]
10. Myeloperoxidase expression as a potential determinant of parthenolide-induced apoptosis in leukemia bulk and leukemia stem cells.
Kim YR; Eom JI; Kim SJ; Jeung HK; Cheong JW; Kim JS; Min YH
J Pharmacol Exp Ther; 2010 Nov; 335(2):389-400. PubMed ID: 20699435
[TBL] [Abstract][Full Text] [Related]
11. Chaetocin-mediated SUV39H1 inhibition targets stemness and oncogenic networks of diffuse midline gliomas and synergizes with ONC201.
Xin DE; Liao Y; Rao R; Ogurek S; Sengupta S; Xin M; Bayat AE; Seibel WL; Graham RT; Koschmann C; Lu QR
Neuro Oncol; 2024 Apr; 26(4):735-748. PubMed ID: 38011799
[TBL] [Abstract][Full Text] [Related]
12. Chaetocin-induced ROS-mediated apoptosis involves ATM-YAP1 axis and JNK-dependent inhibition of glucose metabolism.
Dixit D; Ghildiyal R; Anto NP; Sen E
Cell Death Dis; 2014 May; 5(5):e1212. PubMed ID: 24810048
[TBL] [Abstract][Full Text] [Related]
13. A novel ring-substituted diindolylmethane,1,1-bis[3'-(5-methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia.
Contractor R; Samudio IJ; Estrov Z; Harris D; McCubrey JA; Safe SH; Andreeff M; Konopleva M
Cancer Res; 2005 Apr; 65(7):2890-8. PubMed ID: 15805291
[TBL] [Abstract][Full Text] [Related]
14. The ROS/SUMO axis contributes to the response of acute myeloid leukemia cells to chemotherapeutic drugs.
Bossis G; Sarry JE; Kifagi C; Ristic M; Saland E; Vergez F; Salem T; Boutzen H; Baik H; Brockly F; Pelegrin M; Kaoma T; Vallar L; Récher C; Manenti S; Piechaczyk M
Cell Rep; 2014 Jun; 7(6):1815-23. PubMed ID: 24910433
[TBL] [Abstract][Full Text] [Related]
15. Gfi-1 is the transcriptional repressor of SOCS1 in acute myeloid leukemia cells.
Lee MC; Kuo YY; Chou WC; Hou HA; Hsiao M; Tien HF
J Leukoc Biol; 2014 Jan; 95(1):105-15. PubMed ID: 24018353
[TBL] [Abstract][Full Text] [Related]
16. The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia.
Konopleva M; Tsao T; Estrov Z; Lee RM; Wang RY; Jackson CE; McQueen T; Monaco G; Munsell M; Belmont J; Kantarjian H; Sporn MB; Andreeff M
Cancer Res; 2004 Nov; 64(21):7927-35. PubMed ID: 15520199
[TBL] [Abstract][Full Text] [Related]
17. Downregulation of c-Myc determines sensitivity to 2-methoxyestradiol-induced apoptosis in human acute myeloid leukemia.
Chow JM; Liu CR; Lin CP; Lee CN; Cheng YC; Lin S; Liu HE
Exp Hematol; 2008 Feb; 36(2):140-8. PubMed ID: 18206725
[TBL] [Abstract][Full Text] [Related]
18. The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma.
Ozyerli-Goknar E; Sur-Erdem I; Seker F; Cingöz A; Kayabolen A; Kahya-Yesil Z; Uyulur F; Gezen M; Tolay N; Erman B; Gönen M; Dunford J; Oppermann U; Bagci-Onder T
Cell Death Dis; 2019 Nov; 10(12):894. PubMed ID: 31772153
[TBL] [Abstract][Full Text] [Related]
19. 15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
Shin SW; Seo CY; Han H; Han JY; Jeong JS; Kwak JY; Park JI
Clin Cancer Res; 2009 Sep; 15(17):5414-25. PubMed ID: 19690198
[TBL] [Abstract][Full Text] [Related]
20. SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation.
Vaquero A; Scher M; Erdjument-Bromage H; Tempst P; Serrano L; Reinberg D
Nature; 2007 Nov; 450(7168):440-4. PubMed ID: 18004385
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
