418 related articles for article (PubMed ID: 21981925)
1. Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase.
Faesen AC; Dirac AM; Shanmugham A; Ovaa H; Perrakis A; Sixma TK
Mol Cell; 2011 Oct; 44(1):147-59. PubMed ID: 21981925
[TBL] [Abstract][Full Text] [Related]
2. C-terminal region of USP7/HAUSP is critical for deubiquitination activity and contains a second mdm2/p53 binding site.
Ma J; Martin JD; Xue Y; Lor LA; Kennedy-Wilson KM; Sinnamon RH; Ho TF; Zhang G; Schwartz B; Tummino PJ; Lai Z
Arch Biochem Biophys; 2010 Nov; 503(2):207-12. PubMed ID: 20816748
[TBL] [Abstract][Full Text] [Related]
3. Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP.
Holowaty MN; Sheng Y; Nguyen T; Arrowsmith C; Frappier L
J Biol Chem; 2003 Nov; 278(48):47753-61. PubMed ID: 14506283
[TBL] [Abstract][Full Text] [Related]
4. Molecular recognition of p53 and MDM2 by USP7/HAUSP.
Sheng Y; Saridakis V; Sarkari F; Duan S; Wu T; Arrowsmith CH; Frappier L
Nat Struct Mol Biol; 2006 Mar; 13(3):285-91. PubMed ID: 16474402
[TBL] [Abstract][Full Text] [Related]
5. USP7/HAUSP promotes the sequence-specific DNA binding activity of p53.
Sarkari F; Sheng Y; Frappier L
PLoS One; 2010 Sep; 5(9):e13040. PubMed ID: 20885946
[TBL] [Abstract][Full Text] [Related]
6. Structure of USP7 catalytic domain and three Ubl-domains reveals a connector α-helix with regulatory role.
Kim RQ; van Dijk WJ; Sixma TK
J Struct Biol; 2016 Jul; 195(1):11-8. PubMed ID: 27183903
[TBL] [Abstract][Full Text] [Related]
7. Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7.
Pfoh R; Lacdao IK; Georges AA; Capar A; Zheng H; Frappier L; Saridakis V
PLoS Pathog; 2015 Jun; 11(6):e1004950. PubMed ID: 26046769
[TBL] [Abstract][Full Text] [Related]
8. STIP is a critical nuclear scaffolding protein linking USP7 to p53-Mdm2 pathway regulation.
Ye M; Tang Y; Tang S; Liu J; Wu K; Yao S; Sun Y; Zhou L; Deng T; Chen Y; Huang C; Tan W
Oncotarget; 2015 Oct; 6(33):34718-31. PubMed ID: 26460617
[TBL] [Abstract][Full Text] [Related]
9. Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation.
Rougé L; Bainbridge TW; Kwok M; Tong R; Di Lello P; Wertz IE; Maurer T; Ernst JA; Murray J
Structure; 2016 Aug; 24(8):1335-1345. PubMed ID: 27452404
[TBL] [Abstract][Full Text] [Related]
10. (1)H, (13)C and (15)N backbone resonance assignment for the 40.5 kDa catalytic domain of Ubiquitin Specific Protease 7 (USP7).
Di Lello P; Rougé L; Pan B; Maurer T
Biomol NMR Assign; 2016 Oct; 10(2):345-9. PubMed ID: 27386854
[TBL] [Abstract][Full Text] [Related]
11. HAUSP/USP7 as an Epstein-Barr virus target.
Holowaty MN; Frappier L
Biochem Soc Trans; 2004 Nov; 32(Pt 5):731-2. PubMed ID: 15494000
[TBL] [Abstract][Full Text] [Related]
12. Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway.
Hu M; Gu L; Li M; Jeffrey PD; Gu W; Shi Y
PLoS Biol; 2006 Feb; 4(2):e27. PubMed ID: 16402859
[TBL] [Abstract][Full Text] [Related]
13. HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response.
Lim KH; Park JJ; Gu BH; Kim JO; Park SG; Baek KH
Sci Rep; 2015 Aug; 5():12793. PubMed ID: 26238070
[TBL] [Abstract][Full Text] [Related]
14. The role of UBL domains in ubiquitin-specific proteases.
Faesen AC; Luna-Vargas MP; Sixma TK
Biochem Soc Trans; 2012 Jun; 40(3):539-45. PubMed ID: 22616864
[TBL] [Abstract][Full Text] [Related]
15. GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7.
van der Knaap JA; Kumar BR; Moshkin YM; Langenberg K; Krijgsveld J; Heck AJ; Karch F; Verrijzer CP
Mol Cell; 2005 Mar; 17(5):695-707. PubMed ID: 15749019
[TBL] [Abstract][Full Text] [Related]
16. Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells.
Colland F; Formstecher E; Jacq X; Reverdy C; Planquette C; Conrath S; Trouplin V; Bianchi J; Aushev VN; Camonis J; Calabrese A; Borg-Capra C; Sippl W; Collura V; Boissy G; Rain JC; Guedat P; Delansorne R; Daviet L
Mol Cancer Ther; 2009 Aug; 8(8):2286-95. PubMed ID: 19671755
[TBL] [Abstract][Full Text] [Related]
17. Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity.
Kim RQ; Geurink PP; Mulder MPC; Fish A; Ekkebus R; El Oualid F; van Dijk WJ; van Dalen D; Ovaa H; van Ingen H; Sixma TK
Nat Commun; 2019 Jan; 10(1):231. PubMed ID: 30651545
[TBL] [Abstract][Full Text] [Related]
18. Nucleotide biosynthetic enzyme GMP synthase is a TRIM21-controlled relay of p53 stabilization.
Reddy BA; van der Knaap JA; Bot AG; Mohd-Sarip A; Dekkers DH; Timmermans MA; Martens JW; Demmers JA; Verrijzer CP
Mol Cell; 2014 Feb; 53(3):458-70. PubMed ID: 24462112
[TBL] [Abstract][Full Text] [Related]
19. USP7 controls Chk1 protein stability by direct deubiquitination.
Alonso-de Vega I; Martín Y; Smits VA
Cell Cycle; 2014; 13(24):3921-6. PubMed ID: 25483066
[TBL] [Abstract][Full Text] [Related]
20. USP7 small-molecule inhibitors interfere with ubiquitin binding.
Kategaya L; Di Lello P; Rougé L; Pastor R; Clark KR; Drummond J; Kleinheinz T; Lin E; Upton JP; Prakash S; Heideker J; McCleland M; Ritorto MS; Alessi DR; Trost M; Bainbridge TW; Kwok MCM; Ma TP; Stiffler Z; Brasher B; Tang Y; Jaishankar P; Hearn BR; Renslo AR; Arkin MR; Cohen F; Yu K; Peale F; Gnad F; Chang MT; Klijn C; Blackwood E; Martin SE; Forrest WF; Ernst JA; Ndubaku C; Wang X; Beresini MH; Tsui V; Schwerdtfeger C; Blake RA; Murray J; Maurer T; Wertz IE
Nature; 2017 Oct; 550(7677):534-538. PubMed ID: 29045385
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]