186 related articles for article (PubMed ID: 21983441)
1. Effect of the leukotriene A4 hydrolase aminopeptidase augmentor 4-methoxydiphenylmethane in a pre-clinical model of pulmonary emphysema.
De Oliveira EO; Wang K; Kong HS; Kim S; Miessau M; Snelgrove RJ; Shim YM; Paige M
Bioorg Med Chem Lett; 2011 Nov; 21(22):6746-50. PubMed ID: 21983441
[TBL] [Abstract][Full Text] [Related]
2. Role of leukotriene A4 hydrolase aminopeptidase in the pathogenesis of emphysema.
Paige M; Wang K; Burdick M; Park S; Cha J; Jeffery E; Sherman N; Shim YM
J Immunol; 2014 Jun; 192(11):5059-68. PubMed ID: 24771855
[TBL] [Abstract][Full Text] [Related]
3. Role of LTB₄ in the pathogenesis of elastase-induced murine pulmonary emphysema.
Shim YM; Paige M; Hanna H; Kim SH; Burdick MD; Strieter RM
Am J Physiol Lung Cell Mol Physiol; 2010 Dec; 299(6):L749-59. PubMed ID: 20817777
[TBL] [Abstract][Full Text] [Related]
4. Saccharomyces cerevisiae leukotriene A4 hydrolase: formation of leukotriene B4 and identification of catalytic residues.
Kull F; Ohlson E; Lind B; Haeggström JZ
Biochemistry; 2001 Oct; 40(42):12695-703. PubMed ID: 11601994
[TBL] [Abstract][Full Text] [Related]
5. Leukotriene A4 hydrolase/aminopeptidase. Glutamate 271 is a catalytic residue with specific roles in two distinct enzyme mechanisms.
Rudberg PC; Tholander F; Thunnissen MM; Haeggström JZ
J Biol Chem; 2002 Jan; 277(2):1398-404. PubMed ID: 11675384
[TBL] [Abstract][Full Text] [Related]
6. Modification of leukotriene A(4) hydrolase/aminopeptidase by sulfhydryl-blocking reagents: differential effects on dual enzyme activities by methyl-methane thiosulfonate.
Orning L; Fitzpatrick FA
Arch Biochem Biophys; 1999 Aug; 368(1):131-8. PubMed ID: 10415120
[TBL] [Abstract][Full Text] [Related]
7. Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors.
Numao S; Hasler F; Laguerre C; Srinivas H; Wack N; Jäger P; Schmid A; Osmont A; Röthlisberger P; Houguenade J; Bergsdorf C; Dawson J; Carte N; Hofmann A; Markert C; Hardaker L; Billich A; Wolf RM; Penno CA; Bollbuck B; Miltz W; Röhn TA
Sci Rep; 2017 Oct; 7(1):13591. PubMed ID: 29051536
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of leukotriene A4 hydrolase/aminopeptidase by captopril.
Orning L; Krivi G; Bild G; Gierse J; Aykent S; Fitzpatrick FA
J Biol Chem; 1991 Sep; 266(25):16507-11. PubMed ID: 1885582
[TBL] [Abstract][Full Text] [Related]
9. Hybrid Receptor-Bound/MM-GBSA-Per-residue Energy-Based Pharmacophore Modelling: Enhanced Approach for Identification of Selective LTA4H Inhibitors as Potential Anti-inflammatory Drugs.
Appiah-Kubi P; Soliman M
Cell Biochem Biophys; 2017 Mar; 75(1):35-48. PubMed ID: 27914004
[TBL] [Abstract][Full Text] [Related]
10. Effect of alpha lipoic acid on leukotriene A
Torres MJ; Fierro A; Pessoa-Mahana CD; Romero-Parra J; Cabrera G; Faúndez M
Eur J Pharmacol; 2017 Mar; 799():41-47. PubMed ID: 28132911
[TBL] [Abstract][Full Text] [Related]
11. Evidence for a leukotriene A4 hydrolase in Xenopus laevis skin exudate.
Clamagirand C; Cadel S; Barre N; Cohen P
FEBS Lett; 1998 Aug; 433(1-2):68-72. PubMed ID: 9738935
[TBL] [Abstract][Full Text] [Related]
12. Effect of Modifier Structure on the Activation of Leukotriene A
Lee KH; Petruncio G; Shim A; Burdick M; Zhang Z; Shim YM; Noble SM; Paige M
J Med Chem; 2019 Dec; 62(23):10605-10616. PubMed ID: 31751136
[TBL] [Abstract][Full Text] [Related]
13. Mutation of tyrosine 383 in leukotriene A4 hydrolase allows conversion of leukotriene A4 into 5S,6S-dihydroxy-7,9-trans-11,14-cis-eicosatetraenoic acid. Implications for the epoxide hydrolase mechanism.
Andberg MB; Hamberg M; Haeggström JZ
J Biol Chem; 1997 Sep; 272(37):23057-63. PubMed ID: 9287304
[TBL] [Abstract][Full Text] [Related]
14. Leukotriene A4 hydrolase.
Haeggström JZ; Kull F; Rudberg PC; Tholander F; Thunnissen MM
Prostaglandins Other Lipid Mediat; 2002 Aug; 68-69():495-510. PubMed ID: 12432939
[TBL] [Abstract][Full Text] [Related]
15. Aminopeptidase B is structurally related to leukotriene-A4 hydrolase but is not a bifunctional enzyme with epoxide hydrolase activity.
Fukasawa KM; Fukasawa K; Harada M; Hirose J; Izumi T; Shimizu T
Biochem J; 1999 May; 339 ( Pt 3)(Pt 3):497-502. PubMed ID: 10215585
[TBL] [Abstract][Full Text] [Related]
16. Leukotriene A4 hydrolase, insights into the molecular evolution by homology modeling and mutational analysis of enzyme from Saccharomyces cerevisiae.
Tholander F; Kull F; Ohlson E; Shafqat J; Thunnissen MM; Haeggström JZ
J Biol Chem; 2005 Sep; 280(39):33477-86. PubMed ID: 16024909
[TBL] [Abstract][Full Text] [Related]
17. Characterization of the aminopeptidase activity of epidermal leukotriene A4 hydrolase against the opioid dynorphin fragment 1-7.
Nissen JB; Iversen L; Kragballe K
Br J Dermatol; 1995 Nov; 133(5):742-9. PubMed ID: 8555027
[TBL] [Abstract][Full Text] [Related]
18. The bifunctional enzyme leukotriene-A4 hydrolase is an arginine aminopeptidase of high efficiency and specificity.
Orning L; Gierse JK; Fitzpatrick FA
J Biol Chem; 1994 Apr; 269(15):11269-73. PubMed ID: 8157657
[TBL] [Abstract][Full Text] [Related]
19. Leukotriene A4 hydrolase, a bifunctional enzyme. Distinction of leukotriene A4 hydrolase and aminopeptidase activities by site-directed mutagenesis at Glu-297.
Minami M; Bito H; Ohishi N; Tsuge H; Miyano M; Mori M; Wada H; Mutoh H; Shimada S; Izumi T
FEBS Lett; 1992 Sep; 309(3):353-7. PubMed ID: 1516710
[TBL] [Abstract][Full Text] [Related]
20. Purification and characterization of leukotriene A4 hydrolase from Xenopus laevis oocytes.
Strömberg-Kull F; Haeggström JZ
FEBS Lett; 1998 Aug; 433(3):219-22. PubMed ID: 9744798
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
