BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

315 related articles for article (PubMed ID: 21983831)

  • 1. The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells.
    Chuang HC; Lan JL; Chen DY; Yang CY; Chen YM; Li JP; Huang CY; Liu PE; Wang X; Tan TH
    Nat Immunol; 2011 Oct; 12(11):1113-8. PubMed ID: 21983831
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and phospholipase C gamma 1 are required for NF-kappa B activation and lipid raft recruitment of protein kinase C theta induced by T cell costimulation.
    Dienz O; Möller A; Strecker A; Stephan N; Krammer PH; Dröge W; Schmitz ML
    J Immunol; 2003 Jan; 170(1):365-72. PubMed ID: 12496421
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta.
    Lin X; O'Mahony A; Mu Y; Geleziunas R; Greene WC
    Mol Cell Biol; 2000 Apr; 20(8):2933-40. PubMed ID: 10733597
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation.
    Lee KY; D'Acquisto F; Hayden MS; Shim JH; Ghosh S
    Science; 2005 Apr; 308(5718):114-8. PubMed ID: 15802604
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The protein phosphatase 2A regulatory subunit B56γ mediates suppression of T cell receptor (TCR)-induced nuclear factor-κB (NF-κB) activity.
    Breuer R; Becker MS; Brechmann M; Mock T; Arnold R; Krammer PH
    J Biol Chem; 2014 May; 289(21):14996-5004. PubMed ID: 24719332
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ZAP-70 and SLP-76 regulate protein kinase C-theta and NF-kappa B activation in response to engagement of CD3 and CD28.
    Herndon TM; Shan XC; Tsokos GC; Wange RL
    J Immunol; 2001 May; 166(9):5654-64. PubMed ID: 11313406
    [TBL] [Abstract][Full Text] [Related]  

  • 7. T-cell receptor-induced NF-kappaB activation is negatively regulated by E3 ubiquitin ligase Cbl-b.
    Qiao G; Li Z; Molinero L; Alegre ML; Ying H; Sun Z; Penninger JM; Zhang J
    Mol Cell Biol; 2008 Apr; 28(7):2470-80. PubMed ID: 18227156
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role for protein kinase Ctheta (PKCtheta) in TCR/CD28-mediated signaling through the canonical but not the non-canonical pathway for NF-kappaB activation.
    Li Y; Sedwick CE; Hu J; Altman A
    J Biol Chem; 2005 Jan; 280(2):1217-23. PubMed ID: 15536066
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MAP4K Family Kinases in Immunity and Inflammation.
    Chuang HC; Wang X; Tan TH
    Adv Immunol; 2016; 129():277-314. PubMed ID: 26791862
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Complex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation cascade in Jurkat T cells.
    Bauer B; Krumböck N; Fresser F; Hochholdinger F; Spitaler M; Simm A; Uberall F; Schraven B; Baier G
    J Biol Chem; 2001 Aug; 276(34):31627-34. PubMed ID: 11410591
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes.
    Sun Z; Arendt CW; Ellmeier W; Schaeffer EM; Sunshine MJ; Gandhi L; Annes J; Petrzilka D; Kupfer A; Schwartzberg PL; Littman DR
    Nature; 2000 Mar; 404(6776):402-7. PubMed ID: 10746729
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein kinase C-theta-mediated signals enhance CD4+ T cell survival by up-regulating Bcl-xL.
    Manicassamy S; Gupta S; Huang Z; Sun Z
    J Immunol; 2006 Jun; 176(11):6709-16. PubMed ID: 16709830
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The physical association of protein kinase C theta with a lipid raft-associated inhibitor of kappa B factor kinase (IKK) complex plays a role in the activation of the NF-kappa B cascade by TCR and CD28.
    Khoshnan A; Bae D; Tindell CA; Nel AE
    J Immunol; 2000 Dec; 165(12):6933-40. PubMed ID: 11120819
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential requirement of PKC-theta in the development and function of natural regulatory T cells.
    Gupta S; Manicassamy S; Vasu C; Kumar A; Shang W; Sun Z
    Mol Immunol; 2008 Dec; 46(2):213-24. PubMed ID: 18842300
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein kinase Calpha (PKCalpha) acts upstream of PKCtheta to activate IkappaB kinase and NF-kappaB in T lymphocytes.
    Trushin SA; Pennington KN; Carmona EM; Asin S; Savoy DN; Billadeau DD; Paya CV
    Mol Cell Biol; 2003 Oct; 23(19):7068-81. PubMed ID: 12972622
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comment on "PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation".
    Gruber T; Freeley M; Thuille N; Heit I; Shaw S; Long A; Baier G
    Science; 2006 Apr; 312(5770):55; author reply 55. PubMed ID: 16601177
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TCR-induced, PKC-θ-mediated NF-κB activation is regulated by a caspase-8-caspase-9-caspase-3 cascade.
    Zhao Y; Lei M; Wang Z; Qiao G; Yang T; Zhang J
    Biochem Biophys Res Commun; 2014 Jul; 450(1):526-31. PubMed ID: 24924627
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transition from heterotypic to homotypic PDK1 homodimerization is essential for TCR-mediated NF-κB activation.
    Kang JA; Jeong SP; Park D; Hayden MS; Ghosh S; Park SG
    J Immunol; 2013 May; 190(9):4508-15. PubMed ID: 23530144
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.
    Cannons JL; Wu JZ; Gomez-Rodriguez J; Zhang J; Dong B; Liu Y; Shaw S; Siminovitch KA; Schwartzberg PL
    J Immunol; 2010 Sep; 185(5):2819-27. PubMed ID: 20668219
    [TBL] [Abstract][Full Text] [Related]  

  • 20. GLK-IKKβ signaling induces dimerization and translocation of the AhR-RORγt complex in IL-17A induction and autoimmune disease.
    Chuang HC; Tsai CY; Hsueh CH; Tan TH
    Sci Adv; 2018 Sep; 4(9):eaat5401. PubMed ID: 30214937
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.