BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

316 related articles for article (PubMed ID: 21983831)

  • 61. PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis.
    Healy AM; Izmailova E; Fitzgerald M; Walker R; Hattersley M; Silva M; Siebert E; Terkelsen J; Picarella D; Pickard MD; LeClair B; Chandra S; Jaffee B
    J Immunol; 2006 Aug; 177(3):1886-93. PubMed ID: 16849501
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Different effects of bortezomib on the expressions of various protein kinase C isoenzymes in T cells of patients with systemic lupus erythematosus and in Jurkat cells.
    Griger Z; Tóth BI; Baráth S; Gyetvai Á; Kovács I; Tarr T; Bíró T; Zeher M; Sipka S
    Scand J Immunol; 2012 Feb; 75(2):243-8. PubMed ID: 21988336
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes.
    Baier-Bitterlich G; Uberall F; Bauer B; Fresser F; Wachter H; Grunicke H; Utermann G; Altman A; Baier G
    Mol Cell Biol; 1996 Apr; 16(4):1842-50. PubMed ID: 8657160
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses.
    Marsland BJ; Soos TJ; Späth G; Littman DR; Kopf M
    J Exp Med; 2004 Jul; 200(2):181-9. PubMed ID: 15263025
    [TBL] [Abstract][Full Text] [Related]  

  • 65. Protein kinase C-alpha is an upstream activator of the IkappaB kinase complex in the TPA signal transduction pathway to NF-kappaB in U2OS cells.
    Vertegaal AC; Kuiperij HB; Yamaoka S; Courtois G; van der Eb AJ; Zantema A
    Cell Signal; 2000 Dec; 12(11-12):759-68. PubMed ID: 11152962
    [TBL] [Abstract][Full Text] [Related]  

  • 66. AKT1/PKBalpha is recruited to lipid rafts and activated downstream of PKC isotypes in CD3-induced T cell signaling.
    Bauer B; Jenny M; Fresser F; Uberall F; Baier G
    FEBS Lett; 2003 Apr; 541(1-3):155-62. PubMed ID: 12706837
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation.
    Bi K; Tanaka Y; Coudronniere N; Sugie K; Hong S; van Stipdonk MJ; Altman A
    Nat Immunol; 2001 Jun; 2(6):556-63. PubMed ID: 11376344
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Protein kinase C-θ inhibits inducible regulatory T cell differentiation via an AKT-Foxo1/3a-dependent pathway.
    Ma J; Ding Y; Fang X; Wang R; Sun Z
    J Immunol; 2012 Jun; 188(11):5337-47. PubMed ID: 22539794
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Phytocomponent 4-hydroxy-3-methoxycinnamaldehyde ablates T-cell activation by targeting protein kinase C-θ and its downstream pathways.
    Akber U; Na BR; Ko YS; Lee HS; Kim HR; Kwon MS; Park ZY; Choi EJ; Han WC; Lee SH; Oh HM; Jun CD
    Int Immunopharmacol; 2015 Mar; 25(1):130-40. PubMed ID: 25637768
    [TBL] [Abstract][Full Text] [Related]  

  • 70. Protein kinase C η is required for T cell activation and homeostatic proliferation.
    Fu G; Hu J; Niederberger-Magnenat N; Rybakin V; Casas J; Yachi PP; Feldstein S; Ma B; Hoerter JA; Ampudia J; Rigaud S; Lambolez F; Gavin AL; Sauer K; Cheroutre H; Gascoigne NR
    Sci Signal; 2011 Dec; 4(202):ra84. PubMed ID: 22155788
    [TBL] [Abstract][Full Text] [Related]  

  • 71. Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: relationship to differentiation and survival of PC12 cells.
    Wooten MW; Seibenhener ML; Neidigh KB; Vandenplas ML
    Mol Cell Biol; 2000 Jul; 20(13):4494-504. PubMed ID: 10848576
    [TBL] [Abstract][Full Text] [Related]  

  • 72. Synergistic action of protein kinase C theta and calcineurin is sufficient for Fas ligand expression and induction of a crmA-sensitive apoptosis pathway in Jurkat T cells.
    Villunger A; Ghaffari-Tabrizi N; Tinhofer I; Krumböck N; Bauer B; Schneider T; Kasibhatla S; Greil R; Baier-Bitterlich G; Uberall F; Green DR; Baier G
    Eur J Immunol; 1999 Nov; 29(11):3549-61. PubMed ID: 10556809
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Paclitaxel-induced immune suppression is associated with NF-kappaB activation via conventional PKC isotypes in lipopolysaccharide-stimulated 70Z/3 pre-B lymphocyte tumor cells.
    Lee M; Jeon YJ
    Mol Pharmacol; 2001 Feb; 59(2):248-53. PubMed ID: 11160860
    [TBL] [Abstract][Full Text] [Related]  

  • 74. PKC-θ is a negative regulator of TRAIL-induced and FADD-mediated apoptotic spectrin aggregation.
    Michalczyk I; Toporkiewicz M; Dubielecka PM; Chorzalska A; Sikorski AF
    Folia Histochem Cytobiol; 2016; 54(1):1-13. PubMed ID: 27094638
    [TBL] [Abstract][Full Text] [Related]  

  • 75. Protein kinase C theta modulates nuclear receptor-corepressor interaction during T cell activation.
    Ishaq M; DeGray G; Natarajan V
    J Biol Chem; 2003 Oct; 278(41):39296-302. PubMed ID: 12890684
    [TBL] [Abstract][Full Text] [Related]  

  • 76. Investigating small molecules to inhibit germinal center kinase-like kinase (GLK/MAP4K3) upstream of PKCθ phosphorylation: Potential therapy to modulate T cell dependent immunity.
    May-Dracka TL; Arduini R; Bertolotti-Ciarlet A; Bhisetti G; Brickelmaier M; Cahir-McFarland E; Enyedy I; Fontenot JD; Hesson T; Little K; Lyssikatos J; Marcotte D; McKee T; Murugan P; Patterson T; Peng H; Rushe M; Silvian L; Spilker K; Wu P; Xin Z; Burkly LC
    Bioorg Med Chem Lett; 2018 Jun; 28(10):1964-1971. PubMed ID: 29636220
    [TBL] [Abstract][Full Text] [Related]  

  • 77. Protein kinase Ctheta, a selective upstream regulator of JNK/SAPK and IL-2 promoter activation in Jurkat T cells.
    Ghaffari-Tabrizi N; Bauer B; Villunger A; Baier-Bitterlich G; Altman A; Utermann G; Uberall F; Baier G
    Eur J Immunol; 1999 Jan; 29(1):132-42. PubMed ID: 9933094
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Aplotaxene blocks T cell activation by modulation of protein kinase C-θ-dependent pathway.
    Na BR; Kim HR; Kwon MS; Lee HS; Piragyte I; Choi EJ; Choi HK; Han WC; Lee SH; Jun CD
    Food Chem Toxicol; 2013 Dec; 62():23-31. PubMed ID: 23941771
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Protein kinase C theta is expressed in mast cells and is functionally involved in Fcepsilon receptor I signaling.
    Liu Y; Graham C; Parravicini V; Brown MJ; Rivera J; Shaw S
    J Leukoc Biol; 2001 May; 69(5):831-40. PubMed ID: 11358993
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Protein kinase C and calcineurin synergize to activate IkappaB kinase and NF-kappaB in T lymphocytes.
    Trushin SA; Pennington KN; Algeciras-Schimnich A; Paya CV
    J Biol Chem; 1999 Aug; 274(33):22923-31. PubMed ID: 10438457
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.