213 related articles for article (PubMed ID: 21985704)
1. Entropy-driven binding of picomolar transition state analogue inhibitors to human 5'-methylthioadenosine phosphorylase.
Guan R; Ho MC; Brenowitz M; Tyler PC; Evans GB; Almo SC; Schramm VL
Biochemistry; 2011 Nov; 50(47):10408-17. PubMed ID: 21985704
[TBL] [Abstract][Full Text] [Related]
2. Thermodynamic analysis of transition-state features in picomolar inhibitors of human 5'-methylthioadenosine phosphorylase.
Guan R; Tyler PC; Evans GB; Schramm VL
Biochemistry; 2013 Nov; 52(46):8313-22. PubMed ID: 24148083
[TBL] [Abstract][Full Text] [Related]
3. Heat Capacity Changes for Transition-State Analogue Binding and Catalysis with Human 5'-Methylthioadenosine Phosphorylase.
Firestone RS; Cameron SA; Karp JM; Arcus VL; Schramm VL
ACS Chem Biol; 2017 Feb; 12(2):464-473. PubMed ID: 28026167
[TBL] [Abstract][Full Text] [Related]
4. Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A.
Singh V; Shi W; Evans GB; Tyler PC; Furneaux RH; Almo SC; Schramm VL
Biochemistry; 2004 Jan; 43(1):9-18. PubMed ID: 14705926
[TBL] [Abstract][Full Text] [Related]
5. Altered enthalpy-entropy compensation in picomolar transition state analogues of human purine nucleoside phosphorylase.
Edwards AA; Mason JM; Clinch K; Tyler PC; Evans GB; Schramm VL
Biochemistry; 2009 Jun; 48(23):5226-38. PubMed ID: 19425594
[TBL] [Abstract][Full Text] [Related]
6. Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues.
Rinaldo-Matthis A; Wing C; Ghanem M; Deng H; Wu P; Gupta A; Tyler PC; Evans GB; Furneaux RH; Almo SC; Wang CC; Schramm VL
Biochemistry; 2007 Jan; 46(3):659-68. PubMed ID: 17223688
[TBL] [Abstract][Full Text] [Related]
7. The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A resolution provides insights into substrate binding and catalysis.
Appleby TC; Erion MD; Ealick SE
Structure; 1999 Jun; 7(6):629-41. PubMed ID: 10404592
[TBL] [Abstract][Full Text] [Related]
8. Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase.
Evans GB; Furneaux RH; Schramm VL; Singh V; Tyler PC
J Med Chem; 2004 Jun; 47(12):3275-81. PubMed ID: 15163207
[TBL] [Abstract][Full Text] [Related]
9. Intracellular rebinding of transition-state analogues provides extended
Gebre ST; Cameron SA; Li L; Babu YS; Schramm VL
J Biol Chem; 2017 Sep; 292(38):15907-15915. PubMed ID: 28794158
[TBL] [Abstract][Full Text] [Related]
10. Transition state analogues in quorum sensing and SAM recycling.
Schramm VL; Gutierrez JA; Cordovano G; Basu I; Guha C; Belbin TJ; Evans GB; Tyler PC; Furneaux RH
Nucleic Acids Symp Ser (Oxf); 2008; (52):75-6. PubMed ID: 18776260
[TBL] [Abstract][Full Text] [Related]
11. Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis.
Bzowska A; Koellner G; Wielgus-Kutrowska B; Stroh A; Raszewski G; HolĂ˝ A; Steiner T; Frank J
J Mol Biol; 2004 Sep; 342(3):1015-32. PubMed ID: 15342253
[TBL] [Abstract][Full Text] [Related]
12. Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase.
Kicska GA; Tyler PC; Evans GB; Furneaux RH; Shi W; Fedorov A; Lewandowicz A; Cahill SM; Almo SC; Schramm VL
Biochemistry; 2002 Dec; 41(49):14489-98. PubMed ID: 12463747
[TBL] [Abstract][Full Text] [Related]
13. Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase.
Evans GB; Furneaux RH; Lenz DH; Painter GF; Schramm VL; Singh V; Tyler PC
J Med Chem; 2005 Jul; 48(14):4679-89. PubMed ID: 16000004
[TBL] [Abstract][Full Text] [Related]
14. Transition state analogue of MTAP extends lifespan of APC
Firestone RS; Feng M; Basu I; Peregrina K; Augenlicht LH; Schramm VL
Sci Rep; 2021 Apr; 11(1):8844. PubMed ID: 33893330
[TBL] [Abstract][Full Text] [Related]
15. Transition State Analogues Enhanced by Fragment-Based Structural Analysis: Bacterial Methylthioadenosine Nucleosidases.
Zhang D; Burdette BE; Wang Z; Karn K; Li HY; Schramm VL; Tyler PC; Evans GB; Wang S
Biochemistry; 2020 Feb; 59(7):831-835. PubMed ID: 32022543
[TBL] [Abstract][Full Text] [Related]
16. Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition.
Taylor EA; Rinaldo-Matthis A; Li L; Ghanem M; Hazleton KZ; Cassera MB; Almo SC; Schramm VL
Biochemistry; 2007 Oct; 46(43):12405-15. PubMed ID: 17918964
[TBL] [Abstract][Full Text] [Related]
17. Catalytic site cooperativity in dimeric methylthioadenosine nucleosidase.
Wang S; Thomas K; Schramm VL
Biochemistry; 2014 Mar; 53(9):1527-35. PubMed ID: 24502544
[TBL] [Abstract][Full Text] [Related]
18. L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase.
Rinaldo-Matthis A; Murkin AS; Ramagopal UA; Clinch K; Mee SP; Evans GB; Tyler PC; Furneaux RH; Almo SC; Schramm VL
J Am Chem Soc; 2008 Jan; 130(3):842-4. PubMed ID: 18154341
[TBL] [Abstract][Full Text] [Related]
19. Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
Lee JE; Singh V; Evans GB; Tyler PC; Furneaux RH; Cornell KA; Riscoe MK; Schramm VL; Howell PL
J Biol Chem; 2005 May; 280(18):18274-82. PubMed ID: 15746096
[TBL] [Abstract][Full Text] [Related]
20. Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase.
Basu I; Locker J; Cassera MB; Belbin TJ; Merino EF; Dong X; Hemeon I; Evans GB; Guha C; Schramm VL
J Biol Chem; 2011 Feb; 286(6):4902-11. PubMed ID: 21135097
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]