These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 21987377)

  • 1. 75-kd sirtuin 1 blocks tumor necrosis factor α-mediated apoptosis in human osteoarthritic chondrocytes.
    Oppenheimer H; Gabay O; Meir H; Haze A; Kandel L; Liebergall M; Gagarina V; Lee EJ; Dvir-Ginzberg M
    Arthritis Rheum; 2012 Mar; 64(3):718-28. PubMed ID: 21987377
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tumor necrosis factor α-mediated cleavage and inactivation of SirT1 in human osteoarthritic chondrocytes.
    Dvir-Ginzberg M; Gagarina V; Lee EJ; Booth R; Gabay O; Hall DJ
    Arthritis Rheum; 2011 Aug; 63(8):2363-73. PubMed ID: 21305533
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway.
    Gagarina V; Gabay O; Dvir-Ginzberg M; Lee EJ; Brady JK; Quon MJ; Hall DJ
    Arthritis Rheum; 2010 May; 62(5):1383-92. PubMed ID: 20131294
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Serum NT/CT SIRT1 ratio reflects early osteoarthritis and chondrosenescence.
    Batshon G; Elayyan J; Qiq O; Reich E; Ben-Aderet L; Kandel L; Haze A; Steinmeyer J; Lefebvre V; Zhang H; Elisseeff J; Henrotin Y; Mobasheri A; Dvir-Ginzberg M
    Ann Rheum Dis; 2020 Oct; 79(10):1370-1380. PubMed ID: 32665267
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial biogenesis is impaired in osteoarthritis chondrocytes but reversible via peroxisome proliferator-activated receptor γ coactivator 1α.
    Wang Y; Zhao X; Lotz M; Terkeltaub R; Liu-Bryan R
    Arthritis Rheumatol; 2015 May; 67(8):2141-53. PubMed ID: 25940958
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TRAIL induces apoptosis of chondrocytes and influences the pathogenesis of experimentally induced rat osteoarthritis.
    Lee SW; Lee HJ; Chung WT; Choi SM; Rhyu SH; Kim DK; Kim KT; Kim JY; Kim JM; Yoo YH
    Arthritis Rheum; 2004 Feb; 50(2):534-42. PubMed ID: 14872496
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Vascular endothelial growth factor activities on osteoarthritic chondrocytes.
    Pulsatelli L; Dolzani P; Silvestri T; Frizziero L; Facchini A; Meliconi R
    Clin Exp Rheumatol; 2005; 23(4):487-93. PubMed ID: 16095117
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sam68 Promotes NF-κB Activation and Apoptosis Signaling in Articular Chondrocytes during Osteoarthritis.
    Xu L; Sun C; Zhang S; Xu X; Zhai L; Wang Y; Wang S; Liu Z; Cheng H; Xiao M; Tao R; Zhang D
    Inflamm Res; 2015 Nov; 64(11):895-902. PubMed ID: 26350037
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1β and tumor necrosis factor α.
    Terkeltaub R; Yang B; Lotz M; Liu-Bryan R
    Arthritis Rheum; 2011 Jul; 63(7):1928-37. PubMed ID: 21400477
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ADAM-12 (meltrin alpha) is involved in chondrocyte proliferation via cleavage of insulin-like growth factor binding protein 5 in osteoarthritic cartilage.
    Okada A; Mochizuki S; Yatabe T; Kimura T; Shiomi T; Fujita Y; Matsumoto H; Sehara-Fujisawa A; Iwamoto Y; Okada Y
    Arthritis Rheum; 2008 Mar; 58(3):778-89. PubMed ID: 18311789
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lysosomal dysfunction in osteoarthritis and aged cartilage triggers apoptosis in chondrocytes through BAX mediated release of Cytochrome c.
    Ansari MY; Ball HC; Wase SJ; Novak K; Haqqi TM
    Osteoarthritis Cartilage; 2021 Jan; 29(1):100-112. PubMed ID: 33161099
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Circ_0001103 alleviates IL-1β-induced chondrocyte cell injuries by upregulating SIRT1 via targeting miR-375.
    Zhang M; Mou L; Liu S; Sun F; Gong M
    Clin Immunol; 2021 Jun; 227():108718. PubMed ID: 33819576
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Potential involvement of SIRT1 in the pathogenesis of osteoarthritis through the modulation of chondrocyte gene expressions.
    Fujita N; Matsushita T; Ishida K; Kubo S; Matsumoto T; Takayama K; Kurosaka M; Kuroda R
    J Orthop Res; 2011 Apr; 29(4):511-5. PubMed ID: 21337390
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prostaglandin PGE2 at very low concentrations suppresses collagen cleavage in cultured human osteoarthritic articular cartilage: this involves a decrease in expression of proinflammatory genes, collagenases and COL10A1, a gene linked to chondrocyte hypertrophy.
    Tchetina EV; Di Battista JA; Zukor DJ; Antoniou J; Poole AR
    Arthritis Res Ther; 2007; 9(4):R75. PubMed ID: 17683641
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cilostazol protects rat chondrocytes against nitric oxide-induced apoptosis in vitro and prevents cartilage destruction in a rat model of osteoarthritis.
    Lee SW; Song YS; Shin SH; Kim KT; Park YC; Park BS; Yun I; Kim K; Lee SY; Chung WT; Lee HJ; Yoo YH
    Arthritis Rheum; 2008 Mar; 58(3):790-800. PubMed ID: 18311796
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibitory effects of SRT1720 on the apoptosis of rabbit chondrocytes by activating SIRT1 via p53/bax and NF-κB/PGC-1α pathways.
    Liu B; Lei M; Hu T; Yu F; Xiao DM; Kang H
    J Huazhong Univ Sci Technolog Med Sci; 2016 Jun; 36(3):350-355. PubMed ID: 27376802
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes.
    Kim J; Xu M; Xo R; Mates A; Wilson GL; Pearsall AW; Grishko V
    Osteoarthritis Cartilage; 2010 Mar; 18(3):424-32. PubMed ID: 19822235
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of CD95 apoptotic signaling by interferon-gamma in human osteoarthritic chondrocytes is associated with increased expression of FLICE inhibitory protein.
    Grassi F; Piacentini A; Cristino S; Toneguzzi S; Facchini A; Lisignoli G
    Arthritis Rheum; 2004 Feb; 50(2):498-506. PubMed ID: 14872492
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Increased chondrocyte sclerostin may protect against cartilage degradation in osteoarthritis.
    Chan BY; Fuller ES; Russell AK; Smith SM; Smith MM; Jackson MT; Cake MA; Read RA; Bateman JF; Sambrook PN; Little CB
    Osteoarthritis Cartilage; 2011 Jul; 19(7):874-85. PubMed ID: 21619935
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of chondrocyte mitochondrial dysfunction on cartilage degeneration: A possible pathway for osteoarthritis pathology at the subcellular level.
    Liu H; Li Z; Cao Y; Cui Y; Yang X; Meng Z; Wang R
    Mol Med Rep; 2019 Oct; 20(4):3308-3316. PubMed ID: 31432161
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.