BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 21987453)

  • 1. Altered store operated calcium entry increases cyclic 3',5'-adenosine monophosphate production and extracellular signal-regulated kinases 1 and 2 phosphorylation in polycystin-2-defective cholangiocytes.
    Spirli C; Locatelli L; Fiorotto R; Morell CM; Fabris L; Pozzan T; Strazzabosco M
    Hepatology; 2012 Mar; 55(3):856-68. PubMed ID: 21987453
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Adenylyl cyclase 5 links changes in calcium homeostasis to cAMP-dependent cyst growth in polycystic liver disease.
    Spirli C; Mariotti V; Villani A; Fabris L; Fiorotto R; Strazzabosco M
    J Hepatol; 2017 Mar; 66(3):571-580. PubMed ID: 27826057
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib.
    Spirli C; Morell CM; Locatelli L; Okolicsanyi S; Ferrero C; Kim AK; Fabris L; Fiorotto R; Strazzabosco M
    Hepatology; 2012 Dec; 56(6):2363-74. PubMed ID: 22653837
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ERK1/2-dependent vascular endothelial growth factor signaling sustains cyst growth in polycystin-2 defective mice.
    Spirli C; Okolicsanyi S; Fiorotto R; Fabris L; Cadamuro M; Lecchi S; Tian X; Somlo S; Strazzabosco M
    Gastroenterology; 2010 Jan; 138(1):360-371.e7. PubMed ID: 19766642
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mammalian target of rapamycin regulates vascular endothelial growth factor-dependent liver cyst growth in polycystin-2-defective mice.
    Spirli C; Okolicsanyi S; Fiorotto R; Fabris L; Cadamuro M; Lecchi S; Tian X; Somlo S; Strazzabosco M
    Hepatology; 2010 May; 51(5):1778-88. PubMed ID: 20131403
    [TBL] [Abstract][Full Text] [Related]  

  • 6. cAMP induces stromal interaction molecule 1 (STIM1) puncta but neither Orai1 protein clustering nor store-operated Ca2+ entry (SOCE) in islet cells.
    Tian G; Tepikin AV; Tengholm A; Gylfe E
    J Biol Chem; 2012 Mar; 287(13):9862-9872. PubMed ID: 22298778
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Posttranslational regulation of polycystin-2 protein expression as a novel mechanism of cholangiocyte reaction and repair from biliary damage.
    Spirli C; Villani A; Mariotti V; Fabris L; Fiorotto R; Strazzabosco M
    Hepatology; 2015 Dec; 62(6):1828-39. PubMed ID: 26313562
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD).
    Banales JM; Masyuk TV; Gradilone SA; Masyuk AI; Medina JF; LaRusso NF
    Hepatology; 2009 Jan; 49(1):160-74. PubMed ID: 19065671
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of a polycystin-1 cleavage product, P100, that regulates store operated Ca entry through interactions with STIM1.
    Woodward OM; Li Y; Yu S; Greenwell P; Wodarczyk C; Boletta A; Guggino WB; Qian F
    PLoS One; 2010 Aug; 5(8):e12305. PubMed ID: 20808796
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The cAMP Signaling Pathway and Direct Protein Kinase A Phosphorylation Regulate Polycystin-2 (TRPP2) Channel Function.
    Cantero Mdel R; Velázquez IF; Streets AJ; Ong AC; Cantiello HF
    J Biol Chem; 2015 Sep; 290(39):23888-96. PubMed ID: 26269590
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Store-operated Ca2+ entry (SOCE) induced by protease-activated receptor-1 mediates STIM1 protein phosphorylation to inhibit SOCE in endothelial cells through AMP-activated protein kinase and p38β mitogen-activated protein kinase.
    Sundivakkam PC; Natarajan V; Malik AB; Tiruppathi C
    J Biol Chem; 2013 Jun; 288(23):17030-17041. PubMed ID: 23625915
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca
    Yanda MK; Liu Q; Cebotaru V; Guggino WB; Cebotaru L
    J Biol Chem; 2017 Oct; 292(43):17897-17908. PubMed ID: 28887310
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential dependence of store-operated and excitation-coupled Ca2+ entry in skeletal muscle on STIM1 and Orai1.
    Lyfenko AD; Dirksen RT
    J Physiol; 2008 Oct; 586(20):4815-24. PubMed ID: 18772199
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of calcium in adult onset polycystic kidney disease.
    Yanda MK; Liu Q; Cebotaru V; Guggino WB; Cebotaru L
    Cell Signal; 2019 Jan; 53():140-150. PubMed ID: 30296477
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Store-Operated Calcium Entry in Müller Glia Is Controlled by Synergistic Activation of TRPC and Orai Channels.
    Molnár T; Yarishkin O; Iuso A; Barabas P; Jones B; Marc RE; Phuong TT; Križaj D
    J Neurosci; 2016 Mar; 36(11):3184-98. PubMed ID: 26985029
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TRPP2 and STIM1 form a microdomain to regulate store-operated Ca
    Guo J; Zhao R; Zhou M; Li J; Yao X; Du J; Chen J; Shen B
    Cell Commun Signal; 2020 Aug; 18(1):138. PubMed ID: 32867798
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms.
    Francis HL; Demorrow S; Franchitto A; Venter JK; Mancinelli RA; White MA; Meng F; Ueno Y; Carpino G; Renzi A; Baker KK; Shine HE; Francis TC; Gaudio E; Alpini GD; Onori P
    Lab Invest; 2012 Feb; 92(2):282-94. PubMed ID: 22064319
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorylation of STIM1 at ERK1/2 target sites modulates store-operated calcium entry.
    Pozo-Guisado E; Campbell DG; Deak M; Alvarez-Barrientos A; Morrice NA; Alvarez IS; Alessi DR; Martín-Romero FJ
    J Cell Sci; 2010 Sep; 123(Pt 18):3084-93. PubMed ID: 20736304
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Urotensin-II promotes vascular smooth muscle cell proliferation through store-operated calcium entry and EGFR transactivation.
    Rodríguez-Moyano M; Díaz I; Dionisio N; Zhang X; Avila-Medina J; Calderón-Sánchez E; Trebak M; Rosado JA; Ordóñez A; Smani T
    Cardiovasc Res; 2013 Nov; 100(2):297-306. PubMed ID: 23933581
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 12.