These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 21989490)

  • 1. Purification of hsp104, a protein disaggregase.
    Sweeny EA; DeSantis ME; Shorter J
    J Vis Exp; 2011 Sep; (55):. PubMed ID: 21989490
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Applying Hsp104 to protein-misfolding disorders.
    Vashist S; Cushman M; Shorter J
    Biochem Cell Biol; 2010 Feb; 88(1):1-13. PubMed ID: 20130674
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanistic and Structural Insights into the Prion-Disaggregase Activity of Hsp104.
    Sweeny EA; Shorter J
    J Mol Biol; 2016 May; 428(9 Pt B):1870-85. PubMed ID: 26608812
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The metazoan protein disaggregase and amyloid depolymerase system: Hsp110, Hsp70, Hsp40, and small heat shock proteins.
    Torrente MP; Shorter J
    Prion; 2013; 7(6):457-63. PubMed ID: 24401655
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Operational plasticity enables hsp104 to disaggregate diverse amyloid and nonamyloid clients.
    DeSantis ME; Leung EH; Sweeny EA; Jackrel ME; Cushman-Nick M; Neuhaus-Follini A; Vashist S; Sochor MA; Knight MN; Shorter J
    Cell; 2012 Nov; 151(4):778-793. PubMed ID: 23141537
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system.
    Shorter J
    PLoS One; 2011; 6(10):e26319. PubMed ID: 22022600
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Potentiated Hsp104 variants suppress toxicity of diverse neurodegenerative disease-linked proteins.
    Jackrel ME; Shorter J
    Dis Model Mech; 2014 Oct; 7(10):1175-84. PubMed ID: 25062688
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Spiraling in Control: Structures and Mechanisms of the Hsp104 Disaggregase.
    Shorter J; Southworth DR
    Cold Spring Harb Perspect Biol; 2019 Aug; 11(8):. PubMed ID: 30745294
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Amyloid Fragmentation and Disaggregation in Yeast and Animals.
    Kushnirov VV; Dergalev AA; Alexandrov AI
    Biomolecules; 2021 Dec; 11(12):. PubMed ID: 34944528
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ATP modulates self-perpetuating conformational conversion generating structurally distinct yeast prion amyloids that limit autocatalytic amplification.
    Mahapatra S; Sarbahi A; Punia N; Joshi A; Avni A; Walimbe A; Mukhopadhyay S
    J Biol Chem; 2023 May; 299(5):104654. PubMed ID: 36990219
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hsp104 targets multiple intermediates on the amyloid pathway and suppresses the seeding capacity of Abeta fibrils and protofibrils.
    Arimon M; Grimminger V; Sanz F; Lashuel HA
    J Mol Biol; 2008 Dec; 384(5):1157-73. PubMed ID: 18851977
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hsp104 antagonizes alpha-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease.
    Lo Bianco C; Shorter J; Régulier E; Lashuel H; Iwatsubo T; Lindquist S; Aebischer P
    J Clin Invest; 2008 Sep; 118(9):3087-97. PubMed ID: 18704197
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Engineering enhanced protein disaggregases for neurodegenerative disease.
    Jackrel ME; Shorter J
    Prion; 2015; 9(2):90-109. PubMed ID: 25738979
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Towards a unifying mechanism for ClpB/Hsp104-mediated protein disaggregation and prion propagation.
    Haslberger T; Bukau B; Mogk A
    Biochem Cell Biol; 2010 Feb; 88(1):63-75. PubMed ID: 20130680
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure and function of the molecular chaperone Hsp104 from yeast.
    Grimminger-Marquardt V; Lashuel HA
    Biopolymers; 2010 Mar; 93(3):252-76. PubMed ID: 19768774
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The small heat shock protein Hsp31 cooperates with Hsp104 to modulate Sup35 prion aggregation.
    Aslam K; Tsai CJ; Hazbun TR
    Prion; 2016 Nov; 10(6):444-465. PubMed ID: 27690738
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tuning Hsp104 specificity to selectively detoxify α-synuclein.
    Mack KL; Kim H; Barbieri EM; Lin J; Braganza S; Jackrel ME; DeNizio JE; Yan X; Chuang E; Tariq A; Cupo RR; Castellano LM; Caldwell KA; Caldwell GA; Shorter J
    Mol Cell; 2023 Sep; 83(18):3314-3332.e9. PubMed ID: 37625404
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The interaction of Hsp104 with yeast prion Sup35 as analyzed by fluorescence cross-correlation spectroscopy.
    Ohta S; Kawai-Noma S; Kitamura A; Pack CG; Kinjo M; Taguchi H
    Biochem Biophys Res Commun; 2013 Dec; 442(1-2):28-32. PubMed ID: 24216111
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of endogenous Hsp104 chaperone in yeast models of sporadic and familial Parkinson's disease.
    Gade VR; Kardani J; Roy I
    Int J Biochem Cell Biol; 2014 Oct; 55():87-92. PubMed ID: 25161148
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Therapeutic genetic variation revealed in diverse Hsp104 homologs.
    March ZM; Sweeney K; Kim H; Yan X; Castellano LM; Jackrel ME; Lin J; Chuang E; Gomes E; Willicott CW; Michalska K; Jedrzejczak RP; Joachimiak A; Caldwell KA; Caldwell GA; Shalem O; Shorter J
    Elife; 2020 Dec; 9():. PubMed ID: 33319748
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.