These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

401 related articles for article (PubMed ID: 21989597)

  • 1. Heterozygous ABCC8 mutations are a cause of MODY.
    Bowman P; Flanagan SE; Edghill EL; Damhuis A; Shepherd MH; Paisey R; Hattersley AT; Ellard S
    Diabetologia; 2012 Jan; 55(1):123-7. PubMed ID: 21989597
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
    Babenko AP; Polak M; Cavé H; Busiah K; Czernichow P; Scharfmann R; Bryan J; Aguilar-Bryan L; Vaxillaire M; Froguel P
    N Engl J Med; 2006 Aug; 355(5):456-66. PubMed ID: 16885549
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutations in the ABCC8 gene encoding the SUR1 subunit of the KATP channel cause transient neonatal diabetes, permanent neonatal diabetes or permanent diabetes diagnosed outside the neonatal period.
    Patch AM; Flanagan SE; Boustred C; Hattersley AT; Ellard S
    Diabetes Obes Metab; 2007 Nov; 9 Suppl 2(Suppl 2):28-39. PubMed ID: 17919176
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes.
    Proks P; Arnold AL; Bruining J; Girard C; Flanagan SE; Larkin B; Colclough K; Hattersley AT; Ashcroft FM; Ellard S
    Hum Mol Genet; 2006 Jun; 15(11):1793-800. PubMed ID: 16613899
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prevalence of permanent neonatal diabetes in Slovakia and successful replacement of insulin with sulfonylurea therapy in KCNJ11 and ABCC8 mutation carriers.
    Stanik J; Gasperikova D; Paskova M; Barak L; Javorkova J; Jancova E; Ciljakova M; Hlava P; Michalek J; Flanagan SE; Pearson E; Hattersley AT; Ellard S; Klimes I
    J Clin Endocrinol Metab; 2007 Apr; 92(4):1276-82. PubMed ID: 17213273
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The spectrum of ABCC8 mutations in Norwegian patients with congenital hyperinsulinism of infancy.
    Sandal T; Laborie LB; Brusgaard K; Eide SA; Christesen HB; Søvik O; Njølstad PR; Molven A
    Clin Genet; 2009 May; 75(5):440-8. PubMed ID: 19475716
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effective treatment with oral sulfonylureas in patients with diabetes due to sulfonylurea receptor 1 (SUR1) mutations.
    Rafiq M; Flanagan SE; Patch AM; Shields BM; Ellard S; Hattersley AT;
    Diabetes Care; 2008 Feb; 31(2):204-9. PubMed ID: 18025408
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutations in ATP-sensitive K+ channel genes cause transient neonatal diabetes and permanent diabetes in childhood or adulthood.
    Flanagan SE; Patch AM; Mackay DJ; Edghill EL; Gloyn AL; Robinson D; Shield JP; Temple K; Ellard S; Hattersley AT
    Diabetes; 2007 Jul; 56(7):1930-7. PubMed ID: 17446535
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Successful sulfonylurea treatment of a neonate with neonatal diabetes mellitus due to a novel missense mutation, p.P1199L, in the ABCC8 gene.
    Oztekin O; Durmaz E; Kalay S; Flanagan SE; Ellard S; Bircan I
    J Perinatol; 2012 Aug; 32(8):645-7. PubMed ID: 22842804
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Permanent neonatal diabetes caused by dominant, recessive, or compound heterozygous SUR1 mutations with opposite functional effects.
    Ellard S; Flanagan SE; Girard CA; Patch AM; Harries LW; Parrish A; Edghill EL; Mackay DJ; Proks P; Shimomura K; Haberland H; Carson DJ; Shield JP; Hattersley AT; Ashcroft FM
    Am J Hum Genet; 2007 Aug; 81(2):375-82. PubMed ID: 17668386
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dominantly acting ABCC8 mutations in patients with medically unresponsive hyperinsulinaemic hypoglycaemia.
    Flanagan SE; Kapoor RR; Banerjee I; Hall C; Smith VV; Hussain K; Ellard S
    Clin Genet; 2011 Jun; 79(6):582-7. PubMed ID: 20573158
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Clinical and metabolic features of adult-onset diabetes caused by ABCC8 mutations.
    Riveline JP; Rousseau E; Reznik Y; Fetita S; Philippe J; Dechaume A; Hartemann A; Polak M; Petit C; Charpentier G; Gautier JF; Froguel P; Vaxillaire M
    Diabetes Care; 2012 Feb; 35(2):248-51. PubMed ID: 22210575
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Coexpression of the type 2 diabetes susceptibility gene variants KCNJ11 E23K and ABCC8 S1369A alter the ATP and sulfonylurea sensitivities of the ATP-sensitive K(+) channel.
    Hamming KS; Soliman D; Matemisz LC; Niazi O; Lang Y; Gloyn AL; Light PE
    Diabetes; 2009 Oct; 58(10):2419-24. PubMed ID: 19587354
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutations in the ABCC8 (SUR1 subunit of the K(ATP) channel) gene are associated with a variable clinical phenotype.
    Klupa T; Kowalska I; Wyka K; Skupien J; Patch AM; Flanagan SE; Noczynska A; Arciszewska M; Ellard S; Hattersley AT; Sieradzki J; Mlynarski W; Malecki MT
    Clin Endocrinol (Oxf); 2009 Sep; 71(3):358-62. PubMed ID: 19021632
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Update of mutations in the genes encoding the pancreatic beta-cell K(ATP) channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes mellitus and hyperinsulinism.
    Flanagan SE; Clauin S; Bellanné-Chantelot C; de Lonlay P; Harries LW; Gloyn AL; Ellard S
    Hum Mutat; 2009 Feb; 30(2):170-80. PubMed ID: 18767144
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults.
    Tarasov AI; Nicolson TJ; Riveline JP; Taneja TK; Baldwin SA; Baldwin JM; Charpentier G; Gautier JF; Froguel P; Vaxillaire M; Rutter GA
    Diabetes; 2008 Jun; 57(6):1595-604. PubMed ID: 18346985
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New ABCC8 mutations in relapsing neonatal diabetes and clinical features.
    Vaxillaire M; Dechaume A; Busiah K; Cavé H; Pereira S; Scharfmann R; de Nanclares GP; Castano L; Froguel P; Polak M;
    Diabetes; 2007 Jun; 56(6):1737-41. PubMed ID: 17389331
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of ABCC8 and KCNJ11 gene mutations and phenotypes in Korean patients with congenital hyperinsulinism.
    Park SE; Flanagan SE; Hussain K; Ellard S; Shin CH; Yang SW
    Eur J Endocrinol; 2011 Jun; 164(6):919-26. PubMed ID: 21422196
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mosaic paternal uniparental isodisomy and an ABCC8 gene mutation in a patient with permanent neonatal diabetes and hemihypertrophy.
    Shield JP; Flanagan SE; Mackay DJ; Harries LW; Proks P; Girard C; Ashcroft FM; Temple IK; Ellard S
    Diabetes; 2008 Jan; 57(1):255-8. PubMed ID: 17942821
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Permanent neonatal diabetes caused by a novel mutation.
    Jain V; Flanagan SE; Ellard S
    Indian Pediatr; 2012 Jun; 49(6):486-8. PubMed ID: 22796691
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.