BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

265 related articles for article (PubMed ID: 21989989)

  • 1. Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.
    Jaako P; Flygare J; Olsson K; Quere R; Ehinger M; Henson A; Ellis S; Schambach A; Baum C; Richter J; Larsson J; Bryder D; Karlsson S
    Blood; 2011 Dec; 118(23):6087-96. PubMed ID: 21989989
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gene therapy cures the anemia and lethal bone marrow failure in a mouse model of RPS19-deficient Diamond-Blackfan anemia.
    Jaako P; Debnath S; Olsson K; Modlich U; Rothe M; Schambach A; Flygare J; Karlsson S
    Haematologica; 2014 Dec; 99(12):1792-8. PubMed ID: 25216681
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia.
    Debnath S; Jaako P; Siva K; Rothe M; Chen J; Dahl M; Gaspar HB; Flygare J; Schambach A; Karlsson S
    Mol Ther; 2017 Aug; 25(8):1805-1814. PubMed ID: 28434866
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gene transfer improves erythroid development in ribosomal protein S19-deficient Diamond-Blackfan anemia.
    Hamaguchi I; Ooka A; Brun A; Richter J; Dahl N; Karlsson S
    Blood; 2002 Oct; 100(8):2724-31. PubMed ID: 12351378
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bone marrow transplantation without myeloablative conditioning in a mouse model for Diamond-Blackfan anemia corrects the disease phenotype.
    Dahl M; Warsi S; Liu Y; Debnath S; Billing M; Siva K; Flygare J; Karlsson S
    Exp Hematol; 2021 Jul; 99():44-53.e2. PubMed ID: 34126174
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proliferation deficiency of multipotent hematopoietic progenitors in ribosomal protein S19 (RPS19)-deficient diamond-Blackfan anemia improves following RPS19 gene transfer.
    Hamaguchi I; Flygare J; Nishiura H; Brun AC; Ooka A; Kiefer T; Ma Z; Dahl N; Richter J; Karlsson S
    Mol Ther; 2003 May; 7(5 Pt 1):613-22. PubMed ID: 12718904
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ribosomal protein S19 deficiency leads to reduced proliferation and increased apoptosis but does not affect terminal erythroid differentiation in a cell line model of Diamond-Blackfan anemia.
    Miyake K; Utsugisawa T; Flygare J; Kiefer T; Hamaguchi I; Richter J; Karlsson S
    Stem Cells; 2008 Feb; 26(2):323-9. PubMed ID: 17962699
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Successful gene therapy of Diamond-Blackfan anemia in a mouse model and human CD34
    Liu Y; Dahl M; Debnath S; Rothe M; Smith EM; Grahn THM; Warsi S; Chen J; Flygare J; Schambach A; Karlsson S
    Haematologica; 2022 Feb; 107(2):446-456. PubMed ID: 33440921
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.
    Jaako P; Debnath S; Olsson K; Bryder D; Flygare J; Karlsson S
    Blood; 2012 Sep; 120(11):2225-8. PubMed ID: 22791294
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells.
    Dutt S; Narla A; Lin K; Mullally A; Abayasekara N; Megerdichian C; Wilson FH; Currie T; Khanna-Gupta A; Berliner N; Kutok JL; Ebert BL
    Blood; 2011 Mar; 117(9):2567-76. PubMed ID: 21068437
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Erythropoiesis failure due to RPS19 deficiency is independent of an activated Tp53 response in a zebrafish model of Diamond-Blackfan anaemia.
    Torihara H; Uechi T; Chakraborty A; Shinya M; Sakai N; Kenmochi N
    Br J Haematol; 2011 Mar; 152(5):648-54. PubMed ID: 21223253
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of cellular models for ribosomal protein S19 (RPS19)-deficient diamond-blackfan anemia using inducible expression of siRNA against RPS19.
    Miyake K; Flygare J; Kiefer T; Utsugisawa T; Richter J; Ma Z; Wiznerowicz M; Trono D; Karlsson S
    Mol Ther; 2005 Apr; 11(4):627-37. PubMed ID: 15771965
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transcriptome analysis of the zebrafish model of Diamond-Blackfan anemia from RPS19 deficiency via p53-dependent and -independent pathways.
    Jia Q; Zhang Q; Zhang Z; Wang Y; Zhang W; Zhou Y; Wan Y; Cheng T; Zhu X; Fang X; Yuan W; Jia H
    PLoS One; 2013; 8(8):e71782. PubMed ID: 23990987
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia.
    Flygare J; Kiefer T; Miyake K; Utsugisawa T; Hamaguchi I; Da Costa L; Richter J; Davey EJ; Matsson H; Dahl N; Wiznerowicz M; Trono D; Karlsson S
    Blood; 2005 Jun; 105(12):4627-34. PubMed ID: 15626736
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p53-Independent cell cycle and erythroid differentiation defects in murine embryonic stem cells haploinsufficient for Diamond Blackfan anemia-proteins: RPS19 versus RPL5.
    Singh SA; Goldberg TA; Henson AL; Husain-Krautter S; Nihrane A; Blanc L; Ellis SR; Lipton JM; Liu JM
    PLoS One; 2014; 9(2):e89098. PubMed ID: 24558476
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An RPS19-edited model for Diamond-Blackfan anemia reveals TP53-dependent impairment of hematopoietic stem cell activity.
    Bhoopalan SV; Yen JS; Mayuranathan T; Mayberry KD; Yao Y; Lillo Osuna MA; Jang Y; Liyanage JS; Blanc L; Ellis SR; Wlodarski MW; Weiss MJ
    JCI Insight; 2023 Jan; 8(1):. PubMed ID: 36413407
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia.
    Devlin EE; Dacosta L; Mohandas N; Elliott G; Bodine DM
    Blood; 2010 Oct; 116(15):2826-35. PubMed ID: 20606162
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A new in-frame deletion in ribosomal protein S19 in a Chinese infant with Diamond-Blackfan anemia.
    Zhang JY; Jia M; Zhao HZ; Luo ZB; Xu WQ; Shen HP; Tang YM
    Blood Cells Mol Dis; 2016 Nov; 62():1-5. PubMed ID: 27732904
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ribosomal protein mutations in Korean patients with Diamond-Blackfan anemia.
    Chae H; Park J; Lee S; Kim M; Kim Y; Lee JW; Chung NG; Cho B; Jeong DC; Kim J; Kim JR; Park G
    Exp Mol Med; 2014 Mar; 46(3):e88. PubMed ID: 24675553
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarray.
    Ebert BL; Lee MM; Pretz JL; Subramanian A; Mak R; Golub TR; Sieff CA
    Blood; 2005 Jun; 105(12):4620-6. PubMed ID: 15755903
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.