These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 21990269)

  • 1. Chemical and pharmacological studies on enantiomerically pure p-methoxytacripyrines, promising multi-target-directed ligands for the treatment of Alzheimer's disease.
    Bartolini M; Pistolozzi M; Andrisano V; Egea J; López MG; Iriepa I; Moraleda I; Gálvez E; Marco-Contelles J; Samadi A
    ChemMedChem; 2011 Nov; 6(11):1990-7. PubMed ID: 21990269
    [No Abstract]   [Full Text] [Related]  

  • 2. Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives.
    de Los Ríos C; Egea J; Marco-Contelles J; León R; Samadi A; Iriepa I; Moraleda I; Gálvez E; García AG; López MG; Villarroya M; Romero A
    J Med Chem; 2010 Jul; 53(14):5129-43. PubMed ID: 20575555
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Recent Developments on Multi-Target-Directed Tacrines for Alzheimer's Disease. I. The Pyranotacrines.
    Romero A; Marco-Contelles J
    Curr Top Med Chem; 2017; 17(31):3328-3335. PubMed ID: 29332586
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents.
    Luo W; Li YP; He Y; Huang SL; Li D; Gu LQ; Huang ZS
    Eur J Med Chem; 2011 Jun; 46(6):2609-16. PubMed ID: 21497959
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies.
    Di Pietro O; Pérez-Areales FJ; Juárez-Jiménez J; Espargaró A; Clos MV; Pérez B; Lavilla R; Sabaté R; Luque FJ; Muñoz-Torrero D
    Eur J Med Chem; 2014 Sep; 84():107-17. PubMed ID: 25016233
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of cholinesterase activity and amyloid aggregation by berberine-phenyl-benzoheterocyclic and tacrine-phenyl-benzoheterocyclic hybrids.
    Huang L; Su T; Shan W; Luo Z; Sun Y; He F; Li X
    Bioorg Med Chem; 2012 May; 20(9):3038-48. PubMed ID: 22472046
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease.
    Chao X; He X; Yang Y; Zhou X; Jin M; Liu S; Cheng Z; Liu P; Wang Y; Yu J; Tan Y; Huang Y; Qin J; Rapposelli S; Pi R
    Bioorg Med Chem Lett; 2012 Oct; 22(20):6498-502. PubMed ID: 22981331
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New Tacrines as Anti-Alzheimer's Disease Agents. The (Benzo)Chromeno- PyranoTacrines.
    Oset-Gasque MJ; Marco-Contelles J
    Curr Top Med Chem; 2017; 17(31):3349-3360. PubMed ID: 29332585
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment.
    Minarini A; Milelli A; Tumiatti V; Rosini M; Simoni E; Bolognesi ML; Andrisano V; Bartolini M; Motori E; Angeloni C; Hrelia S
    Neuropharmacology; 2012 Feb; 62(2):997-1003. PubMed ID: 22032870
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular perception of interactions between bis(7)tacrine and cystamine-tacrine dimer with cholinesterases as the promising proposed agents for the treatment of Alzheimer's disease.
    Eslami M; Hashemianzadeh SM; Bagherzadeh K; Seyed Sajadi SA
    J Biomol Struct Dyn; 2016; 34(4):855-69. PubMed ID: 26043757
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design and synthesis of novel tacrine-indole hybrids as potential multitarget-directed ligands for the treatment of Alzheimer's disease.
    Hamulakova S; Kudlickova Z; Janovec L; Mezencev R; Deckner ZJ; Chernoff YO; Janockova J; Ihnatova V; Bzonek P; Novakova N; Hepnarova V; Hrabinova M; Jun D; Korabecny J; Soukup O; Kuca K
    Future Med Chem; 2021 May; 13(9):785-804. PubMed ID: 33829876
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease.
    Keri RS; Quintanova C; Marques SM; Esteves AR; Cardoso SM; Santos MA
    Bioorg Med Chem; 2013 Aug; 21(15):4559-69. PubMed ID: 23768661
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease.
    Jeřábek J; Uliassi E; Guidotti L; Korábečný J; Soukup O; Sepsova V; Hrabinova M; Kuča K; Bartolini M; Peña-Altamira LE; Petralla S; Monti B; Roberti M; Bolognesi ML
    Eur J Med Chem; 2017 Feb; 127():250-262. PubMed ID: 28064079
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties.
    Fernández-Bachiller MI; Pérez C; González-Muñoz GC; Conde S; López MG; Villarroya M; García AG; Rodríguez-Franco MI
    J Med Chem; 2010 Jul; 53(13):4927-37. PubMed ID: 20545360
    [TBL] [Abstract][Full Text] [Related]  

  • 15. O-Hydroxyl- or o-amino benzylamine-tacrine hybrids: multifunctional biometals chelators, antioxidants, and inhibitors of cholinesterase activity and amyloid-β aggregation.
    Mao F; Huang L; Luo Z; Liu A; Lu C; Xie Z; Li X
    Bioorg Med Chem; 2012 Oct; 20(19):5884-92. PubMed ID: 22944335
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel tacrine-grafted Ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic acid hybrids.
    Benchekroun M; Bartolini M; Egea J; Romero A; Soriano E; Pudlo M; Luzet V; Andrisano V; Jimeno ML; López MG; Wehle S; Gharbi T; Refouvelet B; de Andrés L; Herrera-Arozamena C; Monti B; Bolognesi ML; Rodríguez-Franco MI; Decker M; Marco-Contelles J; Ismaili L
    ChemMedChem; 2015 Mar; 10(3):523-39. PubMed ID: 25537267
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multifunctional tacrine-flavonoid hybrids with cholinergic, β-amyloid-reducing, and metal chelating properties for the treatment of Alzheimer's disease.
    Li SY; Wang XB; Xie SS; Jiang N; Wang KD; Yao HQ; Sun HB; Kong LY
    Eur J Med Chem; 2013 Nov; 69():632-46. PubMed ID: 24095756
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel multipotent phenylthiazole-tacrine hybrids for the inhibition of cholinesterase activity, β-amyloid aggregation and Ca²⁺ overload.
    Wang Y; Wang F; Yu JP; Jiang FC; Guan XL; Wang CM; Li L; Cao H; Li MX; Chen JG
    Bioorg Med Chem; 2012 Nov; 20(21):6513-22. PubMed ID: 23000296
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
    Marco-Contelles J; León R; de los Ríos C; Samadi A; Bartolini M; Andrisano V; Huertas O; Barril X; Luque FJ; Rodríguez-Franco MI; López B; López MG; García AG; Carreiras Mdo C; Villarroya M
    J Med Chem; 2009 May; 52(9):2724-32. PubMed ID: 19374444
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tacrine-melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties.
    Fernández-Bachiller MI; Pérez C; Campillo NE; Páez JA; González-Muñoz GC; Usán P; García-Palomero E; López MG; Villarroya M; García AG; Martínez A; Rodríguez-Franco MI
    ChemMedChem; 2009 May; 4(5):828-41. PubMed ID: 19308922
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.